Clinical oncology

Section edited by: Prof Serigne Magueye Gueye and Prof Jan Vermorken. 

The clinical oncology section represents an opportunity to share experiences and information among worldwide oncologists and to identify and develop diagnostic as well as therapeutic protocols, which are globally valid in the current global village. Potential topics include, but are not limited to: epidemiology, pathology and pathogenesis of cancers and clinical studies

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  1. Review

    Factors associated with the high prevalence of oesophageal cancer in Western Kenya: a review

    Oesophageal carcinoma (OC) is highly prevalent in Western Kenya especially among the members of the Kalenjin community who reside in the Northern and Southern areas of the Rift Valley. Previous authors have su...

    Gabriel Kigen, Naftali Busakhala, Zipporah Kamuren, Hillary Rono, Wilfred Kimalat and Evangeline Njiru

    Infectious Agents and Cancer 2017 12:59

    Published on: 3 November 2017

  2. Review

    A systematic review on multiparametric MR imaging in prostate cancer detection

    Literature data suggest that multi-parametric Magnetic Resonance Imaging (MRI), including morphologic T2-weigthed images (T2-MRI) and functional approaches such as Dynamic Contrast Enhanced-MRI (DCE-MRI), Diff...

    Roberta Fusco, Mario Sansone, Vincenza Granata, Sergio Venanzio Setola and Antonella Petrillo

    Infectious Agents and Cancer 2017 12:57

    Published on: 30 October 2017

  3. Research Article

    T- and NK-cell populations with regulatory phenotype and markers of apoptosis in circulating lymphocytes of patients with CIN3 or microcarcinoma of the cervix: evidence for potential mechanisms of immune suppression

    Processes and mechanisms responsible for systemic immune suppression in early-stage cervical cancer remain substantially underinvestigated. In this work, we focused on studying the frequencies of circulating r...

    Olga V. Kurmyshkina, Pavel I. Kovchur, Ludmila V. Schegoleva and Tatyana O. Volkova

    Infectious Agents and Cancer 2017 12:56

    Published on: 17 October 2017

  4. Research article

    Hepatitis C Virus (HCV) genotypes distribution among hepatocellular carcinoma patients in Southern Italy: a three year retrospective study

    Hepatocellular carcinoma (HCC) is one of the major cause for cancer in the world. Aim of this case-control study was to investigate the distribution pattern of HCV genotypes among HCC patients and suggest whet...

    Arnolfo Petruzziello, Samantha Marigliano, Giovanna Loquercio, Nicola Coppola, Mauro Piccirillo, Maddalena Leongito, Rosa Azzaro, Francesco Izzo and Gerardo Botti

    Infectious Agents and Cancer 2017 12:52

    Published on: 6 October 2017

  5. Research Article

    HIV-1 matrix protein p17 and its variants promote human triple negative breast cancer cell aggressiveness

    The introduction of cART has changed the morbidity and mortality patterns affecting HIV-infected (HIV+) individuals. The risk of breast cancer in HIV+ patients has now approached the general population risk. Howe...

    Francesca Caccuri, Francesca Giordano, Ines Barone, Pietro Mazzuca, Cinzia Giagulli, Sebastiano Andò, Arnaldo Caruso and Stefania Marsico

    Infectious Agents and Cancer 2017 12:49

    Published on: 25 September 2017

  6. Research Article

    Diagnostic value of prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) for early stage HBV related hepatocellular carcinoma

    To evaluate the diagnostic efficacy of prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) for early stage hepatitis virus B (HBV) related hepatocellular carcinoma (HCC).

    Xiumei Wang, Weiwei Zhang, Youde Liu, Wenjing Gong, Ping Sun, Xiangshuo Kong, Miaomiao Yang and Zhihua Wang

    Infectious Agents and Cancer 2017 12:47

    Published on: 23 August 2017

  7. Research Article

    High risk human papilloma viruses (HPVs) are present in benign prostate tissues before development of HPV associated prostate cancer

    Although high risk HPVs are associated with an increased risk of prostate cancer it is not known if they have a causal role. The purpose of this study is to investigate the potential role of human papilloma vi...

    Wendy K. Glenn, Christopher C. Ngan, Timothy G. Amos, Richard J. Edwards, Joshua Swift, Louise Lutze-Mann, Fei Shang, Noel J. Whitaker and James S. Lawson

    Infectious Agents and Cancer 2017 12:46

    Published on: 11 August 2017

  8. Research Article

    Whole-genome analysis of human papillomavirus genotypes 52 and 58 isolated from Japanese women with cervical intraepithelial neoplasia and invasive cervical cancer

    Human papillomavirus genotypes 52 and 58 (HPV52/58) are frequently detected in patients with cervical intraepithelial neoplasia (CIN) and invasive cervical cancer (ICC) in East Asian countries including Japan....

    Yuri Tenjimbayashi, Mamiko Onuki, Yusuke Hirose, Seiichiro Mori, Yoshiyuki Ishii, Takamasa Takeuchi, Nobutaka Tasaka, Toyomi Satoh, Tohru Morisada, Takashi Iwata, Shingo Miyamoto, Koji Matsumoto, Akihiko Sekizawa and Iwao Kukimoto

    Infectious Agents and Cancer 2017 12:44

    Published on: 4 August 2017

  9. Research Article

    Six years genotype distribution of Human Papillomavirus in Calabria Region, Southern Italy: a retrospective study

    Although analysis of the Human papillomavirus (HPV) genotype spread in a particular area has a crucial impact on public health and prevention programmes, there is a lack of epidemiological data regarding HPV i...

    Luisa Galati, Cinzia Peronace, Maria Teresa Fiorillo, Rosanna Masciari, Cristina Giraldi, Salvatore Nisticò, Pasquale Minchella, Vincenzo Maiolo, Giorgio Settimo Barreca, Nadia Marascio, Angelo Giuseppe Lamberti, Aida Giancotti, Maria Gabriella Lepore, Francesca Greco, Maria Vittoria Mauro, Annelisa Borelli…

    Infectious Agents and Cancer 2017 12:43

    Published on: 27 July 2017

  10. Research Article

    Interleukin-17F expression is elevated in hepatitis C patients with fibrosis and hepatocellular carcinoma

    The role of interleukin (IL) 17A in chronic liver diseases had been extensively studied, but the function of IL-17F, which shares a high degree of homology with IL-17A, in the progression of chronic hepatic di...

    Ming-Sian Wu, Chun-Hsiang Wang, Fan-Chen Tseng, Hsuan-Ju Yang, Yin-Chiu Lo, Yi-Ping Kuo, De-Jiun Tsai, Wan-Ting Tsai and Guann-Yi Yu

    Infectious Agents and Cancer 2017 12:42

    Published on: 26 July 2017

  11. Research Article

    Prevalence and characteristics of Epstein–Barr virus-associated gastric carcinomas in Portugal

    Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract and is the third leading cause of cancer death worldwide. Epstein–Barr virus (EBV) has been associated with approximately 1...

    Célia Nogueira, Marta Mota, Rui Gradiz, Maria Augusta Cipriano, Francisco Caramelo, Hugo Cruz, Ana Alarcão, Francisco Castro e Sousa, Fernando Oliveira, Fernando Martinho, João Moura Pereira, Paulo Figueiredo and Maximino Leitão

    Infectious Agents and Cancer 2017 12:41

    Published on: 19 July 2017

  12. Research Article

    Effect of electrochemotherapy on human herpesvirus 8 kinetics in classic Kaposi sarcoma

    Electrochemotherapy (ECT) has shown to be an effective treatment for cutaneous and subcutaneous Kaposi sarcoma (KS) lesions. However, no study has investigated the impact of ECT treatment on the kinetics of hu...

    Noemy Starita, Gianluca Di Monta, Andrea Cerasuolo, Ugo Marone, Anna Maria Anniciello, Gerardo Botti, Luigi Buonaguro, Franco M. Buonaguro and Maria Lina Tornesello

    Infectious Agents and Cancer 2017 12:35

    Published on: 19 June 2017

  13. Review

    The efficacy of Epigallocatechin-3-gallate (green tea) in the treatment of Alzheimer’s disease: an overview of pre-clinical studies and translational perspectives in clinical practice

    Alzheimer’s disease (AD) is a neurodegenerative disorder and the most common form of dementia characterized by cognitive and memory impairment. One of the mechanism involved in the pathogenesis of AD, is the o...

    Marco Cascella, Sabrina Bimonte, Maria Rosaria Muzio, Vincenzo Schiavone and Arturo Cuomo

    Infectious Agents and Cancer 2017 12:36

    Published on: 19 June 2017

  14. Research Article

    LPS promotes resistance to TRAIL-induced apoptosis in pancreatic cancer

    Though TRAIL has been hailed as a promising drug for tumour treatment, it has been observed that many tumour cells have developed escape mechanisms against TRAIL-induced apoptosis. As a receptor of LPS, TLR 4,...

    Katharina Beyer, Lars Ivo Partecke, Felicitas Roetz, Herbert Fluhr, Frank Ulrich Weiss, Claus-Dieter Heidecke and Wolfram von Bernstorff

    Infectious Agents and Cancer 2017 12:30

    Published on: 30 May 2017

  15. Research Article

    Serum EBV antibodies and LMP-1 in Polish patients with oropharyngeal and laryngeal cancer

    The association between Epstein-Barr virus (EBV) and the development of head and neck cancer was reported by many researchers. The aim of the present study was to detect EBV DNA and EBV antibodies in 110 Polis...

    Sylwia Fołtyn, Małgorzata Strycharz-Dudziak, Bartłomiej Drop, Anastazja Boguszewska and Małgorzata Polz-Dacewicz

    Infectious Agents and Cancer 2017 12:31

    Published on: 30 May 2017

  16. Research Article

    Association of hepatitis status with surgical outcomes in patients with dual hepatitis B and C related hepatocellular carcinoma

    The conception that serological hepatitis markers determined surgical prognosis of hepatocellular carcinoma (HCC) associated with hepatitis B (HBV) or hepatitis C (HCV) has been well defined. However, little i...

    Xiu-Tao Fu, Ying-Hong Shi, Jian Zhou, Yuan-Fei Peng, Wei-Ren Liu, Guo-Ming Shi, Qiang Gao, Xiao-Ying Wang, Kang Song, Jia Fan and Zhen-Bin Ding

    Infectious Agents and Cancer 2017 12:28

    Published on: 25 May 2017

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