Articles

Emerging role of human polyomaviruses 6 and 7 in human cancers

Currently 12 human polyomaviruses (HPyVs) have been identified, 6 of which have been associated with human diseases, including cancer. The discovery of the Merkel cell polyomavirus and its role in the etiopath...

Authors: Faisal Klufah, Ghalib Mobaraki, Dan Liu, Raed A. Alharbi, Anna Kordelia Kurz, Ernst Jan M. Speel, Véronique Winnepenninckx and Axel zur Hausen

Lung histopathological findings in COVID-19 disease – a systematic review

Since December 2019, the global burden of the COVID-19 pandemic has increased rapidly and has impacted nearly every country in the world, affecting those who are elderly or with underlying comorbidities or imm...

Authors: Giuseppe Pannone, Vito Carlo Alberto Caponio, Ilenia Sara De Stefano, Maria Antonietta Ramunno, Mario Meccariello, Alessio Agostinone, Maria Carmela Pedicillo, Giuseppe Troiano, Khrystyna Zhurakivska, Tommaso Cassano, Maria Eleonora Bizzoca, Silvana Papagerakis, Franco Maria Buonaguro, Shailesh Advani and Lorenzo Lo Muzio

Malaria and Cancer: a critical review on the established associations and new perspectives

Cancer and malaria both have high incidence rates and are leading causes of mortality worldwide, especially in low and middle-income countries with reduced access to the quality healthcare. The objective of th...

Authors: Toby Ellis, Elvis Eze and Bahijja Tolulope Raimi-Abraham

Vaccination strategy and anti - SARS-CoV-2 S titers in healthcare workers of the INT – IRCCS “Fondazione Pascale” Cancer Center (Naples, Italy)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and the resulting disease, coronavirus disease 2019 (COVID-19), have spread to millions of people globally, requiring the development of b...

Authors: Ernesta Cavalcanti, Maria Antonietta Isgrò, Domenica Rea, Lucia Di Capua, Giusy Trillò, Luigi Russo, Gerardo Botti, Leonardo Miscio, Franco Maria Buonaguro and Attilio Antonio Montano Bianchi

Visual inspection with acetic acid (VIA) positivity among female sex workers: a cross-sectional study highlighting one-year experiences in early detection of pre-cancerous and cancerous cervical lesions in Kampala, Uganda

Although cervical cancer is preventable, most women in sub-Saharan Africa (SSA) do not receive routine screening and few treatment options exist. Female Sex Workers (FSWs) are among the Ugandan female populati...

Authors: Gertrude Namale, Yunia Mayanja, Onesmus Kamacooko, Daniel Bagiire, Agnes Ssali, Janet Seeley, Robert Newton and Anatoli Kamali

Prevalence of late-stage presentation and associated factors of cervical cancer patients in Tikur Anbesa Specialized Hospital, Ethiopia: institutional based cross-sectional study

Cancer of the uterine cervix remains a main public health problem in Sub-Saharan Africa. About two-thirds of patients with cervical cancer were diagnosed at late stage with contributing factors of out-of-pocke...

Authors: Mulugeta Wassie and Beletech Fentie

Genetic instability and anti-HPV immune response as drivers of infertility associated with HPV infection

Human papillomavirus (HPV) is a sexually transmitted infection common among men and women of reproductive age worldwide. HPV viruses are associated with epithelial lesions and cancers. HPV infections have been...

Authors: Maria Isaguliants, Stepan Krasnyak, Olga Smirnova, Vincenza Colonna, Oleg Apolikhin and Franco M. Buonaguro

Combined detection of circulating tumor cells, α-fetoprotein heterogene-3 and α-fetoprotein in the early diagnosis of HCC for the prediction of efficacy, prognosis, recurrence after microwave ablation

Early diagnosis can significantly improve treatment outcomes for hepatocellular carcinoma (HCC) patients. Currently, the dosage of serum alpha fetoprotein (AFP) is widely used in the diagnosis of HCC, but this...

Authors: Jian Zhou, Yue Zhu, Yi Li, Kun Liu, Fei He, Sihuan Xu, Xin Li, Li Li, Junfang Hu and Yan Liu

Authors’ response to “Evaluation of Treatments for HIV-Associated Kaposi Sarcoma in Africa”

Authors: Matthew E. Coldiron, Ana Gabriela Gutierrez Zamudio, Rolanda Manuel, Iza Ciglenecki, Laurence Toutous Trellu and Lucas Molfino

Human immunodeficiency virus-related renal cell carcinoma: a retrospective study of 19 cases

We aimed to investigate basic information, clinical findings, treatments for tumor, pathology, and outcomes of HIV-positive patients diagnosed with renal cell carcinoma (RCC).

Authors: Mengmeng Zhang, Zhiqiang Zhu, Wenrui Xue, Hui Liu and Yu Zhang

Evaluation of treatments for HIV-associated Kaposi sarcoma in Africa

Authors: Susan E. Krown and Margaret Z. Borok

Immunophenotypic characterization of TCR γδ T cells and MAIT cells in HIV-infected individuals developing Hodgkin’s lymphoma

Despite successful combined antiretroviral therapy (cART), the risk of non-AIDS defining cancers (NADCs) remains higher for HIV-infected individuals than the general population. The reason for this increase is...

Authors: Christina K. S. Muller, Julian Spagnuolo, Annette Audigé, Andrew Chancellor, Doris Russenberger, Alexandra U. Scherrer, Matthias Hoffmann, Roger Kouyos, Manuel Battegay, Gennaro De Libero and Roberto F. Speck

Correction to: Discrepancy of p16 immunohistochemical expression and HPV RNA in penile cancer. A multiplex in situ hybridization/immunohistochemistry approach study

An amendment to this paper has been published and can be accessed via the original article.

Authors: Federica Zito Marino, Rosalaura Sabetta, Francesca Pagliuca, Matteo Brunelli, Gabriella Aquino, Sisto Perdonà, Gerardo Botti, Gaetano Facchini, Francesco Fiorentino, Giovanni Di Lauro, Marco De Sio, Ferdinando De Vita, Giorgio Toni, Rodolfo Borges Dos Reis, Luciano Neder and Renato Franco

Discrepancy of p16 immunohistochemical expression and HPV RNA in penile cancer. A multiplex in situ hybridization/immunohistochemistry approach study

The high-risk human papillomavirus (HPV) infection represents one of the main etiologic pathways of penile carcinogenesis in approximately 30–50 % of cases. Several techniques for the detection of HPV are curr...

Authors: Federica Zito Marino, Rosalaura Sabetta, Francesca Pagliuca, Matteo Brunelli, Gabriella Aquino, Sisto Perdonà, Gerardo Botti, Gaetano Facchini, Francesco Fiorentino, Giovanni Di Lauro, Marco De Sio, Ferdinando De Vita, Giorgio Toni, Rodolfo Borges Dos Reis, Luciano Neder and Renato Franco

The prevalence and distribution of human papillomavirus among 10,867 Chinese Han women

To assess the prevalence and distribution of HPV genotypes among Chinese Han women, and to explore the risk of high-grade cervical lesions associated with individual hr-HPV genotypes.

Authors: Chunlei Guo, Hui Du, Jerome L. Belinson, Chun Wang, Xia Huang, Xinfeng Qu and Ruifang Wu

Hepatitis B virus induces sorafenib resistance in liver cancer via upregulation of cIAP2 expression

HBV promotes cell survival by upregulating the expression of the cellular inhibitor of apoptosis protein 2 (cIAP2), however whether it is involved in HBV-induced sorafenib resistance in liver cancer remains un...

Authors: Shouhua Zhang, Nuoya Li, Yanling Sheng, Wen Chen, Qiangliang Ma, Xin Yu, Jianping Lian, Junquan Zeng, Yipeng Yang and Jinlong Yan

The safety and efficacy of Glubran 2 as biliostatic agent in liver resection

Biloma, an encapsulated collection of bile outside the biliary tree, supported by a predominantly iatrogenic biliary fistula, and bile likeage are two of the most important surgical complications after liver r...

Authors: Renato Patrone, Vincenza Granata, Andrea Belli, Raffaele Palaia, Vittorio Albino, Mauro Piccirillo, Roberta Fusco, Fabiana Tatangelo, Guglielmo Nasti, Antonio Avallone and Francesco Izzo

Identification of key genes in hepatitis B associated hepatocellular carcinoma based on WGCNA

Chronic Infection of Hepatitis B virus (HBV) is one risk factor of hepatocellular carcinoma (HCC). Much effort has been made to research the process of HBV-associated HCC, but its molecular mechanisms of carci...

Authors: Chang Liu, Qinghai Dai, Qian Ding, Min Wei and Xiaohong Kong

Protection strategy against outbreak of COVID-19 at a tertiary hematology-oncology: strengths and pitfalls

Due to the worldwide COVID-19 outbreak it is mandatory for health care workers to develop containment strategies. Recently published data showed, that cancer patients might have a higher risk for severe course...

Authors: Dominic Kaddu-Mulindwa, Lorenz Thurner, Moritz Bewarder, Niels Murawski, Manfred Ahlgrimm, Thorsten Pfuhl, Barbara Gärtner, Sigrun Smola and Stephan Stilgenbauer

Type-specific persistence, clearance and incidence of high-risk HPV among screen-positive Rwandan women living with HIV

Persistent infection with high-risk human papillomavirus (hrHPV) is a critical step in cervical carcinogenesis. We report on type-specific hrHPV persistence, clearance and incidence among screen-positive Rwand...

Authors: Gad Murenzi, Patrick Tuyisenge, Faustin Kanyabwisha, Athanase Munyaneza, Benjamin Muhoza, Gallican Kubwimana, Anthere Murangwa, Leon Mutesa, Kathryn Anastos and Philip E. Castle

Circulating cell‐free epstein–barr virus DNA levels and clinical features in Moroccan patients with nasopharyngeal carcinoma

The identification of effective prognosis biomarkers for nasopharyngeal carcinoma (NPC) is crucial to improve treatment and patient outcomes. In the present study, we have attempted to evaluate the correlation...

Authors: Amina Gihbid, Raja Benzeid, Abdellah Faouzi, Jalal Nourlil, Nezha Tawfiq, Nadia Benchakroun, Amal Guensi, Karima Bendahhou, Abdellatif Benider, Naima El Benna, Imane Chaoui, Rachida Cadi, Mohammed El Mzibri and Meriem Khyatti

A 12-year retrospective evaluation of anal pre-cancerous lesions and cancer in people living with HIV-1 infection in the Southeastern U.S

Anal cancer is rare in the general population in both genders in the US, but an increased incidence of anal cáncer (AC) has been reported among people living with HIV-1 infection (PLWH) and little is known amo...

Authors: Yuanfan Ye, Greer A. Burkholder, Amrita Mukherjee, Daniel Chu, Anju Bansal, Staci L. Sudenga, Anna Junkins, Sameer Al Diffalha, Michael S. Saag and Sadeep Shrestha

Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis

Frequent mutations in the nuclear receptor binding SET domain protein 1 (NSD1) gene have been observed in head and neck squamous cell carcinomas (HNSCC). NSD1 encodes a histone 3 lysine-36 methyltransferase. NSD1

Authors: Steven F. Gameiro, Farhad Ghasemi, Peter Y. F. Zeng, Neil Mundi, Christopher J. Howlett, Paul Plantinga, John W. Barrett, Anthony C. Nichols and Joe S. Mymryk

Correction to: High dose rate intra-cavitary brachytherapy with cobalt 60 source for locally advanced cervical cancer: the Zimbabwean experience

An amendment to this paper has been published and can be accessed via the original article.

Authors: Shirley Chibonda, Ntokozo Ndlovu, Nomsa Tsikai, Lameck Munangaidzwa, Sandra Ndarukwa, Albert Nyamhunga and Tinashe Mazhindu

Low level of knowledge about cervical cancer among Ethiopian women: a systematic review and meta-analysis

Cervical cancer is one of the leading causes of malignancies among women in Ethiopia. Knowing the disease could empower women to make an informed decision regarding participation with cervical cancer preventio...

Authors: Awoke Derbie, Daniel Mekonnen, Eyaya Misgan, Yihun Mulugeta Alemu, Yimtubezinash Woldeamanuel and Tamrat Abebe

No evidence for a pathogen associated with pulmonary MALT lymphoma: a metagenomics investigation

Mucosa-associated lymphoid tissue (MALT) lymphoma is generally associated with chronic antigen stimulation: auto-antigens or of microbial origin. Only one study suggested association between Achromobacter xylosox...

Authors: Raphaël Borie, Valérie Caro, Hilario Nunes, Marianne Kambouchner, Aurélie Cazes, Martine Antoine, Bruno Crestani, Karen Leroy, Christiane Copie-Bergman, Aurelia Kwasiborski, Christophe Hennequin, Mathias Vandenbogaert, Véronique Hourdel and Jacques Cadranel

Managing head and neck cancer patients during the COVID-19 pandemic: the experience of a tertiary referral center in southern Italy

The medical community has been deeply involved in fighting the Coronavirus disease 2019 (COVID-19) pandemic and, as a consequence, the care of non-COVID-19 patients has been impacted. However, the treatment of...

Authors: Francesco Longo, Eleonora M. C. Trecca, Aurelio D’Ecclesia, Chiara Copelli, Karim Tewfik, Alfonso Manfuso, Nicola Pederneschi, Annalisa Mastromatteo, Matteo Aldo Russo, Antonio Pansini, Luca M. Lacerenza, Pier Gerardo Marano and Lazzaro Cassano

Survey of HCMV in allogenic and autologous stem cell transplantation by real-time PCR in Kermanshah, west of Iran

Human Cytomegalovirus (HCMV) is the most important viral pathogen in people undergoing bone marrow transplantation (BMT). HCMV detection in the early stages makes is possible to save the patients’ lives throug...

Authors: Mehrdad Payandeh, Mohammad Hossein Zamanian, Bizhan Nomanpour, Mohammad Soroush Farhadi, Alireza Janbakhsh, Mosayeb Rostamian, Azam Elahi, Somayeh Jafari and Mohammad Dehghannejad

Co‐administration of 2’3’-cGAMP STING activator and CpG-C adjuvants with a mutated form of HPV 16 E7 protein leads to tumor growth inhibition in the mouse model

Persistent infection with high-risk genotypes of human papillomavirus (HPV) is the leading cause of cervical cancer. The HPV oncoprotein E7 is constitutively expressed in cervical cancer and considered as an e...

Authors: Fariba Dorostkar, Arash Arashkia, Farzin Roohvand, Zabihollah Shoja, Mohsen Navari, Maryam Mashhadi Abolghasem Shirazi, Zahra Shahosseini, Mohammad Farahmand, Mohammad Sadegh Shams nosrati and Somayeh Jalilvand

Molecular detection of urogenital mollicutes in patients with invasive malignant prostate tumor

The etiology of prostate cancer (PCa) is multiple and complex. Among the causes recently cited are chronic infections engendered by microorganisms that often go unnoticed. A typical illustration of such a case...

Authors: Osama Mohammed Saed Abdul-Wahab, Mishari H. Al-Shyarba, Boutheina Ben Abdelmoumen Mardassi, Nessrine Sassi, Majed Saad Shaya Al Fayi, Hassan Otifi, Abdullah Hassan Al Murea, Béhija Mlik and Elhem Yacoub

Hepatitis C virus cascade of care in the general population, in people with diabetes, and in substance use disorder patients

The aim was to evaluate the hepatitis C virus (HCV) cascade of care in the general population (GP) and in two high-risk populations: patients with diabetes mellitus (DM) and substance users (AS) in treatment i...

Authors: Olivera Djuric, Marco Massari, Marta Ottone, Giorgia Collini, Pamela Mancuso, Massimo Vicentini, Antonio Nicolaci, Angela Zannini, Alessandro Zerbini, Valeria Manicardi, Loreta A. Kondili and Paolo Giorgi Rossi

Global expression of noncoding RNome reveals dysregulation of small RNAs in patients with HTLV-1–associated adult T-cell leukemia: a pilot study

Adult T cell lymphoma/leukemia (ATLL) is a peripheral T-cell neoplasm caused by human T-cell lymphotropic virus-1 (HTLV-1). Small RNAs (sRNAs), including microRNAs (miRNAs), play a pivotal role in the initiati...

Authors: Andrezza Nascimento, Daniela Raguer Valadão de Souza, Rodrigo Pessôa, Anna Julia Pietrobon, Youko Nukui, Juliana Pereira, Jorge Casseb, Augusto César Penalva de Oliveira, Paula Loureiro, Alberto José da Silva Duarte, Patricia Bianca Clissa and Sabri Saeed Sanabani

Association between oncogenic human papillomavirus type 16 and Killian polyp

Killian polyp (KP) is a benign lesion that arises from the maxillary sinus. The etiology of KP is unknown. The aim of this study was to investigate the potential involvement of human papilloma- (HPV) and polyo...

Authors: Lucia Oton-Gonzalez, John Charles Rotondo, Luca Cerritelli, Nicola Malagutti, Carmen Lanzillotti, Ilaria Bononi, Andrea Ciorba, Chiara Bianchini, Chiara Mazziotta, Monica De Mattei, Stefano Pelucchi, Mauro Tognon and Fernanda Martini

Outcomes of AIDS-associated Kaposi sarcoma in Mozambique after treatment with pegylated liposomal doxorubicin

Kaposi’s sarcoma (KS) is a common HIV-associated malignancy frequently associated with poor outcomes. It is the most frequently diagnosed cancer in major cities of Mozambique. Antiretroviral therapy is the cor...

Authors: Matthew E. Coldiron, Ana Gabriela Gutierrez Zamudio, Rolanda Manuel, Gilda Luciano, Barbara Rusch, Iza Ciglenecki, Alex Telnov, Rebecca F. Grais, Laurence Toutous Trellu and Lucas Molfino

High dose rate intra-cavitary brachytherapy with cobalt 60 source for locally advanced cervical cancer: the Zimbabwean experience

Cervical cancer is the fourth commonest cancer in women in the world with the highest regional incidence and mortality seen in Southern, Eastern and Western Africa. It is the commonest cause of cancer morbidit...

Authors: Shirley Chibonda, Ntokozo Ndlovu, Nomsa Tsikai, Lameck Munangaidzwa, Sandra Ndarukwa, Albert Nyamhunga and Tinashe Mazhindu

Clinical characteristics, outcomes, and risk factors for mortality in hospitalized patients with COVID-19 and cancer history: a propensity score-matched study

COVID-19 has caused great concern for patients with underlying medical conditions. We aimed to determine the prognosis of patients with current or previous cancer with either a PCR-confirmed COVID-19 infection...

Authors: Majid Sorouri, Amir Kasaeian, Helia Mojtabavi, Amir Reza Radmard, Shadi Kolahdoozan, Amir Anushiravani, Bardia Khosravi, Seyed Mohammad Pourabbas, Masoud Eslahi, Azin Sirusbakht, Marjan Khodabakhshi, Fatemeh Motamedi, Fatemeh Azizi, Reza Ghanbari, Zeynab Rajabi, Ali Reza Sima…

FDA efficiency for approval process of COVID-19 therapeutics

Coronavirus disease 19 (COVID-19) is an infection caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The pandemic spread of SARS-CoV-2 has resulted in significant health, economi...

Authors: Christine Cassidy, Danielle Dever, Laura Stanbery, Gerald Edelman, Lance Dworkin and John Nemunaitis

An evaluation of solid versus liquid transport media for high-risk HPV detection and cervical cancer screening on self-collected specimens

The solid transport media is a small size card that allows fast, easy DNA extraction from a variety of biological samples. In 2016 we developed a solid media transport card; for that pilot study to control the...

Authors: Hui Du, Xianzhi Duan, Yan Liu, Bin Shi, Wei Zhang, Chun Wang, Xinfen Qu, Juncui Bao, Jingran Li, Chao Zhao, Jing Jiang, Juan Liu, Kejia Wu, Aimin Xiao, Lvfang Duan, Xia Huang…

Malaria during pregnancy and transplacental transfer of Kaposi sarcoma-associated herpesvirus (KSHV) antibodies: a cohort study of Kenyan mother and child pairs

Kaposi sarcoma-associated herpesvirus (KSHV) seroprevalence in sub-Saharan African children can range up to 50% by age 2 years but factors affecting early age of KSHV infection are not well understood. Malaria...

Authors: Katherine R. Sabourin, Sidney Ogolla, Ibrahim I. Daud, Conner L. Jackson, Wendell Miley, Nazzarena Labo, Denise Whitby and Rosemary Rochford

Value of AFP and PIVKA-II in diagnosis of HBV-related hepatocellular carcinoma and prediction of vascular invasion and tumor differentiation

To explore the value of alpha fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) in diagnosis of HBV-related hepatocellular carcinoma (HCC) and their relationship with vascu...

Authors: Yuan-Quan Si, Xiu-Qin Wang, Gang Fan, Chang-Yin Wang, Yuan-Wen Zheng, Xie Song, Cui-Cui Pan, Fu-Lu Chu, Zhan-Feng Liu, Bing-Ru Lu and Zhi-Ming Lu

The clinical and translational research activities at the INT – IRCCS “Fondazione Pascale” cancer center (Naples, Italy) during the COVID-19 pandemic

COVID-19 pandemic following the outbreak in China and Western Europe, where it finally lost the momentum, is now devastating North and South America. It has not been identified the reason and the molecular mec...

Authors: Franco M. Buonaguro, Gerardo Botti, Paolo Antonio Ascierto, Sandro Pignata, Franco Ionna, Paolo Delrio, Antonella Petrillo, Ernesta Cavalcanti, Maurizio Di Bonito, Sisto Perdonà, Michelino De Laurentiis, Francesco Fiore, Raffaele Palaia, Francesco Izzo, Stefania D’Auria, Virginia Rossi…

Novel biomarkers with promising benefits for diagnosis of cervical neoplasia: a systematic review

Cervical cancer screening is slowly transitioning from Pappanicolaou cytologic screening to primary Visual Inspection with Acetic Acid (VIA) or HPV testing as an effort to enhance early detection and treatment...

Authors: Calleb George Onyango, Lilian Ogonda, Bernard Guyah, Clement Shiluli, Gregory Ganda, Omenge Elkanah Orang’o and Kirtika Patel

Uptake of cervical cancer screening service and associated factors among age-eligible women in Ethiopia: systematic review and meta-analysis

Cervical cancer is the leading cause of cancer deaths among women in developing countries. Since cervical cancer is a preventable disease, screening is an important control and prevention strategy, recommended...

Authors: Asteray Assmie Ayenew, Biruk Ferede Zewdu and Azezu Asres Nigussie

Prognostic implication of human papillomavirus types in cervical cancer patients: a systematic review and meta-analysis

To estimate the prognostic relevance of human papillomavirus (HPV) 16 and HPV 18 in patients with cervical cancer.

Authors: Yuanyuan Xu, Yichao Qiu, Shuang Yuan and Hongjing Wang

Evaluation of an isothermal amplification HPV detection assay for primary cervical cancer screening

The aim of this research was to evaluate independently the performance of a new isothermal amplification assay for cervical cancer screening compared to two previously validated PCR-based assays and histologic...

Authors: Wei Zhang, Hui Du, Xia Huang, Chun Wang, Xianzhi Duan, Yan Liu, Bin Shi, Wei Zhang, Xinfeng Qu, Lihui Wei, M. Schiffman, J. L. Belinson and Ruifang Wu

A rapid, high-volume cervical screening project using self-sampling and isothermal PCR HPV testing

Rapid, high-volume screening programs are needed as part of cervical cancer prevention in China.

Authors: Andrew Goldstein, Yang Lei, Lena Goldstein, Amelia Goldstein, Qiao Xu Bai, Juan Felix, Roberta Lipson, Maria Demarco, Mark Schiffman, Didem Egemen, Kanan T. Desai, Sarah Bedell, Janet Gersten, Gail Goldstein, Karen O’Keefe, Casey O’Keefe…

IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis

Schistosoma haematobium, the helminth causing urogenital schistosomiasis, is a known bladder carcinogen. Despite the causal link between S. haematobium and bladder cancer, the underlying mechanisms are poorly und...

Authors: Evaristus C. Mbanefo, Chinwike Terry Agbo, Yuanlong Zhao, Olivia K. Lamanna, Kim H. Thai, Shannon E. Karinshak, Mohammad Afzal Khan, Chi-Ling Fu, Justin I. Odegaard, Irina V. Saltikova, Michael J. Smout, Luke F. Pennington, Mark R. Nicolls, Theodore S. Jardetzky, Alex Loukas, Paul J. Brindley…

The interplay between EBV and KSHV viral products and NF-κB pathway in oncogenesis

Among the DNA tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus (KSHV), account for a considerable percentage of virus-associated cancers. Deregulation of transcription factors signaling pa...

Authors: J. Charostad, M. Nakhaie, A. Dehghani and E. Faghihloo

Designing low-cost, accurate cervical screening strategies that take into account COVID-19: a role for self-sampled HPV typing

We propose an economical cervical screening research and implementation strategy designed to take into account the typically slow natural history of cervical cancer and the severe but hopefully temporary impac...

Authors: Kayode Olusegun Ajenifuja, Jerome Belinson, Andrew Goldstein, Kanan T. Desai, Silvia de Sanjose and Mark Schiffman

Design and feasibility of a novel program of cervical screening in Nigeria: self-sampled HPV testing paired with visual triage

Accelerated global control of cervical cancer would require primary prevention with human papillomavirus (HPV) vaccination in addition to novel screening program strategies that are simple, inexpensive, and ef...

Authors: Kanan T. Desai, Kayode O. Ajenifuja, Adekunbiola Banjo, Clement A. Adepiti, Akiva Novetsky, Cathy Sebag, Mark H. Einstein, Temitope Oyinloye, Tamara R. Litwin, Matt Horning, Fatai Olatunde Olanrewaju, Mufutau Muphy Oripelaye, Esther Afolabi, Oluwole O. Odujoko, Philip E. Castle, Sameer Antani…