Thymoquinone (TQ) is the principal active monomer isolated from the seed of the medicinal plant Nigella sativa. This compound has antitumor effects against various types of cancer including hepatocellular carcinoma (HCC). In this review, Sabrina Bimonte et al. summarize the potential roles of TQ in the prevention and treatment of HCC, by revising the preclinical studies and by highlighting the potential applications of TQ as a therapeutic choice for HCC treatment into clinical practices.
Featured Review: Dissecting the roles of thymoquinone on the prevention and the treatment of hepatocellular carcinoma: an overview on the current state of knowledge
Aims and scope
Infectious Agents and Cancer is an open access, peer-reviewed online journal that encompasses all aspects of basic, clinical, epidemiological and translational research providing an insight into the association between chronic infections and cancer.
The journal welcomes submissions in the pathogen-related cancer areas and other related topics pertinent to the development of therapies for chronic infections and cancer.
Of particular interest are HPV and anogenital cancers (as well as head and neck cancers), EBV and Burkitt lymphoma, HCV/HBV and hepatocellular carcinoma (as well as lymphoproliferative diseases), HHV8 and Kaposi sarcoma, HTLV and leukemia and Cancers in Low- and Middle-income countries.
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Article-processing charge discount for AORTIC members
Infectious Agents and Cancer are proudly affiliated with the African Organization for Research and Training in Cancer (AORTIC). All members of AORTIC receive a 15% discount on the article-processing charge for each article accepted for publication. This discount can be requested during the submission process and will be verified before being applied. Standard waiver rules apply for low-income countries.
AORTIC position statement
The African Organization for Research and Training in Cancer (AORTIC) has published a critical appraisal of the state on cancer research and cancer care in Africa including information on the availability of data on cancer burden, screening and prevention for cancer in Africa, cancer care personnel, treatment modalities, and access to cancer care.
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Dr Franco M Buonaguro, Istituto Nazionale Tumori, Naples, Italy
Dr Sam M Mbulaiteye, National Cancer Institute, Bethesda, USA
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From the blog
Dr Franco M. Buonaguro and Dr Sam M Mbulaiteye, Co-Editors-in-Chief of Infectious Agents and Cancer discuss their opinion on the journal's subject field.
“Cancers related to infectious diseases represent a very significant component of the cancer burden in humans spanning from 20% of all malignancies in industrialized countries to 40% in developing countries. Studies on pathogen-related cancers allow the identification of mechanisms relevant to oncogenesis as well as molecular markers for diagnostic/prognostic methods and targets for therapeutic strategies. Furthermore their relevance is due to the concrete possibility of preventive strategies, which are always cost-effective and can usually be implemented with relatively modest investments. The open access policy of Infectious Agents and Cancer represents a key factor to foster an even participation and contribution by Western as well as Eastern/Southern Countries' colleagues.”
Dr Franco M. Buonaguro, Co-Editor-in-Chief, Infectious Agents and Cancer
“Cancer is the leading cause of death worldwide. The International Agency for Research on Cancer estimates that about 20% of cancers in developed countries and close to 30% of cancers in developing countries have an infectious etiology. These statistics articulate the imperative to study the epidemiology, biology, and response to treatment of infection-associated cancers to establish sound evidence-based approaches to cancer public policy, prevention, and treatment. The open access policy of Infectious Agents and Cancer represents a key component in the broad efforts to foster, accelerate, and reduce disparity in access to scientific information by scientists, public health authorities, and policy markers worldwide.”
Dr Sam M Mbulaiteye, Co-Editor-in-Chief, Infectious Agents and Cancer
Infectious Agents and Cancer is affiliated with the African Organisation for Research & Training In Cancer (AORTIC)
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Annual Journal Metrics
49 days to first decision for reviewed manuscripts only
43 days to first decision for all manuscripts
84 days from submission to acceptance
12 days from acceptance to publication
135 Altmetric Mentions