Skip to main content

Cancer centers in low- and middle-income countries

Section edited by: Dr Kishor Bhatia and Dr Edward Trimble.

This section will provide a platform to showcase detailed features of institutes from low and middle income countries including; activities and resources for prevention, diagnosis, treatment and palliative care (available facilities, health care worker resources, outreach programs, collaborations, research projects, oncology-related training facilities, etc.); funding support from local government, foundations, or privately borne by patients; key features of the cancer center and its partnerships that contribute to its success; challenges, both universal and setting-specific, and how they are addressed; policy and practice implications including discussion of what could be adapted by others, what gaps need to be addressed, and what differences might arise in other settings.

Page 1 of 2

  1. Cervical cancer is the leading cause of cancer deaths among women in developing countries. Since cervical cancer is a preventable disease, screening is an important control and prevention strategy, recommended...

    Authors: Asteray Assmie Ayenew, Biruk Ferede Zewdu and Azezu Asres Nigussie

    Citation: Infectious Agents and Cancer 2020 15:67

    Content type: Research Article

    Published on:

  2. The aim of this research was to evaluate independently the performance of a new isothermal amplification assay for cervical cancer screening compared to two previously validated PCR-based assays and histologic...

    Authors: Wei Zhang, Hui Du, Xia Huang, Chun Wang, Xianzhi Duan, Yan Liu, Bin Shi, Wei Zhang, Xinfeng Qu, Lihui Wei, M. Schiffman, J. L. Belinson and Ruifang Wu

    Citation: Infectious Agents and Cancer 2020 15:65

    Content type: Methodology

    Published on:

  3. Rapid, high-volume screening programs are needed as part of cervical cancer prevention in China.

    Authors: Andrew Goldstein, Yang Lei, Lena Goldstein, Amelia Goldstein, Qiao Xu Bai, Juan Felix, Roberta Lipson, Maria Demarco, Mark Schiffman, Didem Egemen, Kanan T. Desai, Sarah Bedell, Janet Gersten, Gail Goldstein, Karen O’Keefe, Casey O’Keefe…

    Citation: Infectious Agents and Cancer 2020 15:64

    Content type: Research Article

    Published on:

  4. We propose an economical cervical screening research and implementation strategy designed to take into account the typically slow natural history of cervical cancer and the severe but hopefully temporary impac...

    Authors: Kayode Olusegun Ajenifuja, Jerome Belinson, Andrew Goldstein, Kanan T. Desai, Silvia de Sanjose and Mark Schiffman

    Citation: Infectious Agents and Cancer 2020 15:61

    Content type: Commentary

    Published on:

  5. Accelerated global control of cervical cancer would require primary prevention with human papillomavirus (HPV) vaccination in addition to novel screening program strategies that are simple, inexpensive, and ef...

    Authors: Kanan T. Desai, Kayode O. Ajenifuja, Adekunbiola Banjo, Clement A. Adepiti, Akiva Novetsky, Cathy Sebag, Mark H. Einstein, Temitope Oyinloye, Tamara R. Litwin, Matt Horning, Fatai Olatunde Olanrewaju, Mufutau Muphy Oripelaye, Esther Afolabi, Oluwole O. Odujoko, Philip E. Castle, Sameer Antani…

    Citation: Infectious Agents and Cancer 2020 15:60

    Content type: Research Article

    Published on:

  6. Prostatic male genital schistosomiasis and prostate cancer co-existence cases are uncommon however, some studies have indicated that schistosomiasis may trigger development of prostate cancer regardless of age...

    Authors: Emilia T. Choto, Takafira Mduluza, Francisca Mutapi and Moses J. Chimbari

    Citation: Infectious Agents and Cancer 2020 15:59

    Content type: Research Article

    Published on:

  7. Bladder cancer is one of the leading causes of cancer death in adults worldwide. There are various risk factors described for the bladder cancer development including genetic background as well as environmenta...

    Authors: Solmaz Ohadian Moghadam, Kamyar Mansori, Mohammad Reza Nowroozi, Davoud Afshar, Behzad Abbasi and Ali Nowroozi

    Citation: Infectious Agents and Cancer 2020 15:52

    Content type: Research Article

    Published on:

  8. Hepatitis B virus (HBV), along with Hepatitis C virus chronic infection, represents a major risk factor for hepatocellular carcinoma (HCC) development. However, molecular mechanisms involved in the development...

    Authors: Davod Javanmard, Mohammad Najafi, Mohammad Reza Babaei, Mohammad Hadi Karbalaie Niya, Maryam Esghaei, Mahshid Panahi, Fahimeh Safarnezhad Tameshkel, Ahmad Tavakoli, Seyed Mohammad Jazayeri, Hadi Ghaffari, Angila Ataei-Pirkooh, Seyed Hamidreaz Monavari and Farah Bokharaei-Salim

    Citation: Infectious Agents and Cancer 2020 15:37

    Content type: Research Article

    Published on:

  9. Despite the demonstrated role of human Papillomavirus (HPV) in the etiology of cervical cancer and the strong evidence suggesting the importance of HPV in the development of oropharyngeal cancer, several aspects ...

    Authors: Tamy Taianne Suehiro, Gabrielle Marconi Zago Ferreira Damke, Edilson Damke, Paloma Luana Rodrigues de Azevedo Ramos, Marcela de Andrade Pereira Silva, Sandra Marisa Pelloso, Warner K. Huh, Ricardo Argemiro Fonseca Franco, Vânia Ramos Sela da Silva, Isabel Cristina Scarinci and Marcia Edilaine Lopes Consolaro

    Citation: Infectious Agents and Cancer 2020 15:31

    Content type: Short Report

    Published on:

  10. The Human Papillomavirus (HPV) is one of the most common sexually transmitted viruses worldwide. HPV infection in men is a serious clinical issue as they could be considered as a reservoir for inadvertently tr...

    Authors: Mehrdad Davarmanesh, Seyed Mohammad Jazayeri, Mehrouz Dezfulian and Mohammad Javad Gharavi

    Citation: Infectious Agents and Cancer 2020 15:29

    Content type: Research Article

    Published on:

  11. Cervical cancer is a major public health problem. In 2018, globally 569,847 cervical cancer were diagnosed and 311,000 deaths were projected due to this preventable disease. Worldwide, therefore, the cervical ...

    Authors: Dominique Diouf, Gora Diop, Cheikh Ahmadou Tidian Diarra, Aminata Issa Ngom, Khadija Niane, Moussa Ndiaye, Sidy Ka, Oumar Faye and Ahmadou Dem

    Citation: Infectious Agents and Cancer 2020 15:24

    Content type: Research Article

    Published on:

  12. The first HPV vaccines licensed targeted two HPV types responsible for most cervical cancers. A 9-valent vaccine (9vHPV), targeting 5 additional types, was introduced in 2016 and is currently the only HPV vacc...

    Authors: N. J. Murphy, L. R. Bulkow, M. Steinau, E. F. Dunne, E. Meites, L. E. Markowitz, E. R. Unger and T. W. Hennessy

    Citation: Infectious Agents and Cancer 2020 15:13

    Content type: Research Article

    Published on:

  13. Genital infection with certain types of Human papillomavirus (HPV) is a major cause of cervical cancer globally. For early detection of premalignant dysplasia, evidences are coming out on the usefulness of HPV...

    Authors: Awoke Derbie, Daniel Mekonnen, Yimtubezinash Woldeamanuel, Xaveer Van Ostade and Tamrat Abebe

    Citation: Infectious Agents and Cancer 2020 15:9

    Content type: Review

    Published on:

  14. Human papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcin...

    Authors: Nopphamon Na Rangsee, Pattamawadee Yanatatsaneejit, Trairak Pisitkun, Poorichaya Somparn, Pornrutsami Jintaridth and Supachai Topanurak

    Citation: Infectious Agents and Cancer 2020 15:7

    Content type: Research Article

    Published on:

  15. The role of human polyomaviruses (HPyVs) in epithelial tumors such as head and neck carcinomas (HNSCCs) including oral and oropharyngeal carcinomas has not been established. In this study, we evaluated for the...

    Authors: Juan P. Muñoz, Rancés Blanco, Julio C. Osorio, Carolina Oliva, María José Diaz, Diego Carrillo-Beltrán, Rebeca Aguayo, Andrés Castillo, Julio C. Tapia, Gloria M. Calaf, Aldo Gaggero and Francisco Aguayo

    Citation: Infectious Agents and Cancer 2020 15:4

    Content type: Research Article

    Published on:

  16. Describe the characteristics of patients seen at the Cancer Prevention and Control Service at a Peruvian private cancer clinic in 2014.

    Authors: José Revilla-López, Andrea Anampa-Guzmán, Luis Casanova Marquez, Katrina Weeks, Suzanne Pollard, Adriel Olórtegui-Yzú, María Ruiz-Velazco, Alba Davila-Edquen, Daniel Castro-Dorer, Juan Wong-Barrenechea, Jossira Abad-Seminario, Pamela Gonzáles-Ramos, Fiorella Rivera-Sandoval and Carlos Carracedo-Gonzáles

    Citation: Infectious Agents and Cancer 2019 14:44

    Content type: Research Article

    Published on:

    The Correction to this article has been published in Infectious Agents and Cancer 2019 14:50

  17. The WHO Global Initiative for Childhood Cancer launched in 2018 will translate into an additional one million lives saved or a survival rate of at least 60% for children with cancer to be attained by 2030. Thi...

    Authors: Daniela Cristina Stefan

    Citation: Infectious Agents and Cancer 2019 14:34

    Content type: Commentary

    Published on:

  18. The pathogenesis of lung cancer is triggered by a combination of genetic and environmental factors, being the tobacco smoke the most important risk factor. Nevertheless, the incidence of lung cancer in non-smo...

    Authors: Estela Maria Silva, Vânia Sammartino Mariano, Paula Roberta Aguiar Pastrez, Miguel Cordoba Pinto, Emily Montosa Nunes, Laura Sichero, Luisa Lina Villa, Cristovam Scapulatempo-Neto, Kari Juhani Syrjanen and Adhemar Longatto-Filho

    Citation: Infectious Agents and Cancer 2019 14:18

    Content type: Research Article

    Published on:

  19. Despite the high prevalences of Human Papilloma Virus (HPV) infections and cervical cancer in Nigeria, utilization of the HPV vaccine as a highly effective preventive measure remains low. The aim of this study...

    Authors: Adaobi I. Bisi-Onyemaechi, Ugo N. Chikani and Obinna Nduagubam

    Citation: Infectious Agents and Cancer 2018 13:29

    Content type: Research Article

    Published on:

  20. Non-Hodgkin lymphoma (NHL) is the most common cancer in people with HIV. Although 95% of HIV patients are in developing countries like Peru, the majority of these studies have been conducted in developed count...

    Authors: Luis Ernesto Cuellar, Andrea Anampa-Guzmán, Alexis Manuel Holguín, Juan Velarde, Diana Portillo-Alvarez, Marco Antonio Zuñiga-Ninaquispe, Esther Rosa Luna-Reyes, Jule Vásquez, Joanne Marie Jeter and Karen Marie Winkfield

    Citation: Infectious Agents and Cancer 2018 13:27

    Content type: Research Article

    Published on:

  21. Aberrant glycosylation is a characteristic of tumour cells. The expression of certain glycan structures has been associated with poor prognosis. In cervical carcinoma, changes in the expression levels of some ...

    Authors: Miguel Aco-Tlachi, Ricardo Carreño-López, Patricia L. Martínez-Morales, Paola Maycotte, Adriana Aguilar-Lemarroy, Luis Felipe Jave-Suárez, Gerardo Santos-López, Julio Reyes-Leyva and Verónica Vallejo-Ruiz

    Citation: Infectious Agents and Cancer 2018 13:25

    Content type: Research Article

    Published on:

  22. The impact of different anti-virus regimens on prognosis of Chronic hepatitis B (CHB) related cirrhosis remains to be explored. We aim to investigate whether CHB-related HCC patients receiving nucleoside analo...

    Authors: Jing Sun, Yanfang Li, Yanna Wang, Yanyan Liu, Youde Liu and Xiumei Wang

    Citation: Infectious Agents and Cancer 2018 13:17

    Content type: Research Article

    Published on:

  23. This study aimed to evaluate trends and predictors of survival after cancer diagnosis in persons living with HIV in the Caribbean, Central, and South America network for HIV epidemiology cohort.

    Authors: Valeria I. Fink, Cathy A. Jenkins, Jessica L. Castilho, Anna K. Person, Bryan E. Shepherd, Beatriz Grinsztejn, Juliana Netto, Brenda Crabtree-Ramirez, Claudia P. Cortés, Denis Padgett, Karu Jayathilake, Catherine McGowan and Pedro Cahn

    Citation: Infectious Agents and Cancer 2018 13:16

    Content type: Research Article

    Published on:

  24. Cervical cancer (CC) is the leading cause of morbidity and mortality from cancer in Nepalese women. Nearly all cases of CC are caused by infection with certain genotypes of human papillomavirus (HPV). Data on ...

    Authors: Sunil Kumar Sah, Joaquin V. González, Sadina Shrestha, Anurag Adhikari, Krishna Das Manandhar, Shyam Babu Yadav, David A. Stein, Birendra Prasad Gupta and María Alejandra Picconi

    Citation: Infectious Agents and Cancer 2018 13:4

    Content type: Research Article

    Published on:

  25. Following the well-established relationship between human papillomavirus (HPV) and cervical carcinoma, the carcinogenicity of this virus has also been confirmed in subsets of head and neck carcinoma (HNCA), bu...

    Authors: Warut Pongsapich, Nitathip Eakkasem, Sontana Siritantikorn, Paveena Pithuksurachai, Kshidej Bongsabhikul and Cheerasook Chongkolwatana

    Citation: Infectious Agents and Cancer 2017 12:58

    Content type: Research Article

    Published on:

  26. Esophageal squamous cell carcinoma (ESCC) is a highly lethal malignant tumor. Currently, Human papillomavirus (HPV) is suggested as a potential risk factor for esophageal cancer (EC) in addition to the classic...

    Authors: Allini Mafra da Costa, José Humberto Tavares Guerreiro Fregnani, Paula Roberta Aguiar Pastrez, Vânia Sammartino Mariano, Estela Maria Silva, Cristovam Scapulatempo Neto, Denise Peixoto Guimarães, Luisa Lina Villa, Laura Sichero, Kari Juhani Syrjanen and Adhemar Longatto-Filho

    Citation: Infectious Agents and Cancer 2017 12:54

    Content type: Research Article

    Published on:

  27. Esophageal carcinoma (EC) is one of the major cancers in China. In 1982, Syrjanen first hypothesized the relationship between human papillomavirus (HPV) infection and the development of esophageal cancer. Sinc...

    Authors: Shuying Li, Haie Shen, Zhanjun Liu, Ning Li, Suxian Yang, Ke Zhang and Jintao Li

    Citation: Infectious Agents and Cancer 2017 12:53

    Content type: Research Article

    Published on:

  28. Direct-acting antivirals have been used for decompensated cirrhotic patients with hepatitis C virus (HCV) infection. However, the benefits in Chinese patients with decompensated cirrhosis are unclear.

    Authors: Fanpu Ji, Wenjun Wang, Shuangsuo Dang, Shengbang Wang, Burong Li, Dan Bai, Wenxue Zhao, Hong Deng, Changyin Tian and Zongfang Li

    Citation: Infectious Agents and Cancer 2017 12:48

    Content type: Research Article

    Published on:

  29. In recent years, saprophytic bacteria have been emerging as potential human pathogens causing life-threatening infections in patients with malignancies. However, evidence is lacking concerning such bacteria, p...

    Authors: Balew Arega, Yimtubezinash Wolde-Amanuel, Kelemework Adane, Ezra Belay, Abdulaziz Abubeker and Daniel Asrat

    Citation: Infectious Agents and Cancer 2017 12:40

    Content type: Research Article

    Published on:

  30. Lymphoma is a leading cause of cancer-related death among human immunodeficiency virus (HIV)-infected individuals in the current era of potent anti-retroviral therapy (ART). Globally, mortality after HIV-assoc...

    Authors: Olugbenga Akindele Silas, Chad J. Achenbach, Lifang Hou, Robert L. Murphy, Julie O. Egesie, Solomon A. Sagay, Oche O. Agbaji, Patricia E. Agaba, Jonah Musa, Agabus N. Manasseh, Ezra D. Jatau, Ayuba M. Dauda, Maxwell O. Akanbi and Barnabas M. Mandong

    Citation: Infectious Agents and Cancer 2017 12:34

    Content type: Research Article

    Published on:

    The Erratum to this article has been published in Infectious Agents and Cancer 2017 12:37

  31. Little information on the prevalence of Kaposi’s sarcoma associated herpesvirus (KSHV) among HIV-negative individuals is available from Asia.

    Authors: Tiejun Zhang, Zhenqiu Liu, Jun Wang, Veenu Minhas, Charles Wood, Gary M. Clifford, Na He and Silvia Franceschi

    Citation: Infectious Agents and Cancer 2017 12:32

    Content type: Short Report

    Published on:

  32. Human mammary tumor virus (HMTV) is 90–95% homologous to mouse mammary tumor virus (MMTV), one of the causal agents of murine mammary tumors. HMTV (MMTV-like) sequences were reported to be present in human bre...

    Authors: Thar Htet San, Masayoshi Fujisawa, Soichiro Fushimi, Teizo Yoshimura, Toshiaki Ohara, Lamin Soe, Ngu Wah Min, Ohnmar Kyaw, Xu Yang and Akihiro Matsukawa

    Citation: Infectious Agents and Cancer 2017 12:20

    Content type: Research Article

    Published on:

  33. Human papillomavirus (HPV) is the main etiological agent of cervical cancer, the third most common cancer among women globally and the second most frequent in Mexico. Persistent infection with high-risk HPV ge...

    Authors: Cristina Artaza-Irigaray, María Guadalupe Flores-Miramontes, Dominik Olszewski, María Teresa Magaña-Torres, María Guadalupe López-Cardona, Yelda Aurora Leal-Herrera, Patricia Piña-Sánchez, Luis Felipe Jave-Suárez and Adriana Aguilar-Lemarroy

    Citation: Infectious Agents and Cancer 2017 12:15

    Content type: Research Article

    Published on:

  34. Investigations on the effects of malaria infection on cancer mortality are limited except for the incidence of Burkitt’s lymphoma (BL) in African children. Our previous murine lung cancer model study demonstra...

    Authors: Li Qin, Changzhong Chen, Lili Chen, Ran Xue, Ming Ou-Yang, Chengzhi Zhou, Siting Zhao, Zhengxiang He, Yu Xia, Jianxing He, Pinghua Liu, Nanshan Zhong and Xiaoping Chen

    Citation: Infectious Agents and Cancer 2017 12:14

    Content type: Research Article

    Published on:

  35. New oral treatments with very high cure rates have the potential to revolutionize global management of hepatitis C virus (HCV), but population-based data on HCV infection are missing in many low and middle-inc...

    Authors: Gary M. Clifford, Tim Waterboer, Bolormaa Dondog, You Lin Qiao, Dimitri Kordzaia, Doudja Hammouda, Namory Keita, Nahid Khodakarami, Syed Ahsan Raza, Ang Tshering Sherpa, Witold Zatonski, Michael Pawlita, Martyn Plummer and Silvia Franceschi

    Citation: Infectious Agents and Cancer 2017 12:9

    Content type: Research Article

    Published on:

  36. In 2000, an Italian non-governmental organisation (NGO) began a 9-year project to establish a surgical pathology laboratory at the Bugando Medical Centre (BMC) in Mwanza, Tanzania, a country with a low Human D...

    Authors: R. Tumino, P. F. Rambau, F. Callea, L. Leoncini, R. Monaco, J. Kahima, V. Stracca Pansa, L. Viberti, D. Amadori, P. Giovenali and K. A. Mteta

    Citation: Infectious Agents and Cancer 2017 12:6

    Content type: Methodology

    Published on:

  37. Chlamydia trachomatis (Ct) is not a disease subject to mandatory reporting in Brazil, and the prevalence rate of this genital infection varies according to the region in which studies ...

    Authors: R. Robial, A. Longatto-Filho, C. M. Roteli-Martins, M. F. Silveira, D. Stauffert, G. G. Ribeiro, I. M. Linhares, M. Tacla, M. A. Zonta and E. C. Baracat

    Citation: Infectious Agents and Cancer 2017 12:3

    Content type: Research Article

    Published on:

  38. Whilst the imputed role of High Risk (HR) HPV infection in the development of cervical lesions and cancer has been established, the high number of HPV genotypes that Female Sex workers (FSW) harbour warrants ...

    Authors: Sonia Menon, Davy van den Broeck, Rodolfo Rossi, Emilomo Ogbe and Hillary Mabeya

    Citation: Infectious Agents and Cancer 2017 12:2

    Content type: Research Article

    Published on:

    The Correction to this article has been published in Infectious Agents and Cancer 2019 14:1

  39. Nasopharyngeal carcinoma (NPC) is the most common cancer arising from the nasopharynx that varies significantly from other cancers of the head and neck in its occurrence, causes, clinical behavior, and treatme...

    Authors: Ali Edris, Mona Ali Mohamed, Nouh S. Mohamed and Emmanuel E. Siddig

    Citation: Infectious Agents and Cancer 2016 11:55

    Content type: Research Article

    Published on:

    The Erratum to this article has been published in Infectious Agents and Cancer 2016 11:60

  40. HPV-16 modifies the overall survival (OS) of patients with oropharyngeal cancer (OPSCC). HPV-16 has been established as risk factor for OPSCC, but HPV-16 infection may also reside in the larynx and oral cavity...

    Authors: Bianca Rivera-Peña, Francisco J. Ruíz-Fullana, Germán L. Vélez-Reyes, Rosa J. Rodriguez-Benitez, María J. Marcos-Martínez, Juan Trinidad-Pinedo and Adriana Báez

    Citation: Infectious Agents and Cancer 2016 11:47

    Content type: Research Article

    Published on:

  41. Hepatitis B virus (HBV) X protein (HBx) reported to be associated with pathogenesis of hepatocellular carcinoma (HCC) and miR-122 expression is down regulated in HCC. Previous studies reported miR-122 targets ...

    Authors: Manikankana Bandopadhyay, Neelakshi Sarkar, Sibnarayan Datta, Dipanwita Das, Ananya Pal, Rajesh Panigrahi, Arup Banerjee, Chinmay K. Panda, Chandrima Das, Shekhar Chakrabarti and Runu Chakravarty

    Citation: Infectious Agents and Cancer 2016 11:40

    Content type: Research Article

    Published on:

  42. HPV is the major etiological factor in the causal pathway for cervical cancer, which is the leading cancer among women in sub-Saharan Africa. HIV is associated with a higher prevalence and a broader range of h...

    Authors: Sonia Simone Menon, Rodolfo Rossi, Ronald Harebottle, Hillary Mabeya and Davy vanden Broeck

    Citation: Infectious Agents and Cancer 2016 11:17

    Content type: Research Article

    Published on:

Annual Journal Metrics