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Clinical oncology

Section edited by: Prof Serigne Magueye Gueye and Prof Jan Vermorken. 

The clinical oncology section represents an opportunity to share experiences and information among worldwide oncologists and to identify and develop diagnostic as well as therapeutic protocols, which are globally valid in the current global village. Potential topics include, but are not limited to: epidemiology, pathology and pathogenesis of cancers and clinical studies

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  1. The etiology of prostate cancer (PCa) is multiple and complex. Among the causes recently cited are chronic infections engendered by microorganisms that often go unnoticed. A typical illustration of such a case...

    Authors: Osama Mohammed Saed Abdul-Wahab, Mishari H. Al-Shyarba, Boutheina Ben Abdelmoumen Mardassi, Nessrine Sassi, Majed Saad Shaya Al Fayi, Hassan Otifi, Abdullah Hassan Al Murea, Béhija Mlik and Elhem Yacoub
    Citation: Infectious Agents and Cancer 2021 16:6
  2. The aim was to evaluate the hepatitis C virus (HCV) cascade of care in the general population (GP) and in two high-risk populations: patients with diabetes mellitus (DM) and substance users (AS) in treatment i...

    Authors: Olivera Djuric, Marco Massari, Marta Ottone, Giorgia Collini, Pamela Mancuso, Massimo Vicentini, Antonio Nicolaci, Angela Zannini, Alessandro Zerbini, Valeria Manicardi, Loreta A. Kondili and Paolo Giorgi Rossi
    Citation: Infectious Agents and Cancer 2021 16:5
  3. COVID-19 has caused great concern for patients with underlying medical conditions. We aimed to determine the prognosis of patients with current or previous cancer with either a PCR-confirmed COVID-19 infection...

    Authors: Majid Sorouri, Amir Kasaeian, Helia Mojtabavi, Amir Reza Radmard, Shadi Kolahdoozan, Amir Anushiravani, Bardia Khosravi, Seyed Mohammad Pourabbas, Masoud Eslahi, Azin Sirusbakht, Marjan Khodabakhshi, Fatemeh Motamedi, Fatemeh Azizi, Reza Ghanbari, Zeynab Rajabi, Ali Reza Sima…
    Citation: Infectious Agents and Cancer 2020 15:74
  4. Coronavirus disease 19 (COVID-19) is an infection caused by the novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The pandemic spread of SARS-CoV-2 has resulted in significant health, economi...

    Authors: Christine Cassidy, Danielle Dever, Laura Stanbery, Gerald Edelman, Lance Dworkin and John Nemunaitis
    Citation: Infectious Agents and Cancer 2020 15:73
  5. The solid transport media is a small size card that allows fast, easy DNA extraction from a variety of biological samples. In 2016 we developed a solid media transport card; for that pilot study to control the...

    Authors: Hui Du, Xianzhi Duan, Yan Liu, Bin Shi, Wei Zhang, Chun Wang, Xinfen Qu, Juncui Bao, Jingran Li, Chao Zhao, Jing Jiang, Juan Liu, Kejia Wu, Aimin Xiao, Lvfang Duan, Xia Huang…
    Citation: Infectious Agents and Cancer 2020 15:72
  6. To explore the value of alpha fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) in diagnosis of HBV-related hepatocellular carcinoma (HCC) and their relationship with vascu...

    Authors: Yuan-Quan Si, Xiu-Qin Wang, Gang Fan, Chang-Yin Wang, Yuan-Wen Zheng, Xie Song, Cui-Cui Pan, Fu-Lu Chu, Zhan-Feng Liu, Bing-Ru Lu and Zhi-Ming Lu
    Citation: Infectious Agents and Cancer 2020 15:70
  7. This study was performed to evaluate the significance of positive resection margins (RMs) with the loop electrosurgical excision procedure combined with cold coagulation (LEEP with CC) as a definitive treatmen...

    Authors: Eun Jung Yang, Nae Ry Kim, Ji Yeon Choi, Wook Youn Kim and Sun Joo Lee
    Citation: Infectious Agents and Cancer 2020 15:58
  8. Hepatocellular carcinoma (HCC) is one of the cancers of highest incidence and mortality worldwide. The proliferation and invasion of tumor cells are the main reason for poor prognosis after HCC surgery. Long n...

    Authors: Quan Liu, Xuxu Yu, Minjie Yang, Xiangke Li, Xuejia Zhai, Yujin Lian, Zhong Chen, Qingxia Fan, Lijie Song and Wencai Li
    Citation: Infectious Agents and Cancer 2020 15:55
  9. Oral squamous cell carcinoma (OSCC) is the most common type of head and neck squamous cell carcinoma (HNSCC), and the effect of zymosan (ZYM), a component of the yeast cell wall, on oral cancer remains unclear...

    Authors: Xu Chen, Qingqiong Luo, Jieying Ding, Meng Yang, Ruiyang Zhang and Fuxiang Chen
    Citation: Infectious Agents and Cancer 2020 15:51
  10. Breast cancer is reported as one of the most common cancers among females worldwide. Infectious agents especially viruses have been considered as role players in the development of breast cancer. Although some...

    Authors: Alireza Khatami, Ali Pormohammad, Rana Farzi, Hassan Saadati, Maryam Mehrabi, Seyed Jalal Kiani and Saied Ghorbani
    Citation: Infectious Agents and Cancer 2020 15:48
  11. HPV causes specific cell-mediated immunity in the cervix. Mononuclear cells such as helper T cells (CD4+), cytotoxic T cells (CD8+), and dendritic cells play a critical role in the initiation of the HPV-specif...

    Authors: Ceyda Sancakli Usta, Eren Altun, Selim Afsar, Cagla Bahar Bulbul, Akin Usta and Ertan Adalı
    Citation: Infectious Agents and Cancer 2020 15:47
  12. Women living with human immunodeficiency virus (WLWH), especially those living in low- and middle-income countries (LMIC), are at increased risk of cervical cancer. The optimal cervical-cancer screening strate...

    Authors: Philip E. Castle, Rogers Ajeh, Anastase Dzudie, Ernestine Kendowo, Norbert Fuhngwa, Andre Gaetan Simo-Wambo, Denis Nsame, Enow Orock, Tiffany M. Hebert, Amanda J. Pierz, Daniel Murokora, Kathryn Anastos and Adebola Adedimeji
    Citation: Infectious Agents and Cancer 2020 15:45
  13. Sinonasal inverted papillomas (SIP) and sinonasal squamous cell carcinomas (SNSCC) are sinonasal tumors with unclear etiology and pathogenesis. Epstein-Barr virus (EBV) has been detected in these tumors but in...

    Authors: Thawaree Nukpook, Tipaya Ekalaksananan, Watchareporn Teeramatwanich, Natcha Patarapadungkit, Surachat Chaiwiriyakul, Patravoot Vatanasapt, Sirinart Aromseree and Chamsai Pientong
    Citation: Infectious Agents and Cancer 2020 15:43
  14. EBV produces miRNAs with important functions in cancer growth, tumor invasion and host immune surveillance. The discovery of EBV miR-BARTs is recent, and most of their functions are still unknown. Nonetheless,...

    Authors: Valli De Re, Laura Caggiari, Mariangela De Zorzi, Valentina Fanotto, Gianmaria Miolo, Fabio Puglisi, Renato Cannizzaro, Vincenzo Canzonieri, Agostino Steffan, Piero Farruggia, Egesta Lopci, Emanuele S. G. d’Amore, Roberta Burnelli, Lara Mussolin and Maurizio Mascarin
    Citation: Infectious Agents and Cancer 2020 15:42
  15. The anatomical complexity of the oropharynx and the difficulty in reaching its distal portion have always conditioned the surgical accessibility.

    Authors: Fraco Ionna, Agostino Guida, Luigi Califano, Gaetano Motta, Giovanni Salzano, Ettore Pavone, Corrado Aversa, Francesco Longo, Salvatore Villano, Ludovica Marcella Ponzo, Pierluigi Franco, Simona Losito, Franco Maria Buonaguro, Maria Lina Tornesello and Maria Grazia Maglione
    Citation: Infectious Agents and Cancer 2020 15:40
  16. Information on HPV-associated sinonasal squamous cell carcinoma (SNSCC) is very limited in China. The aim of this study was to determine the prevalence of HPV in a large cohort of SNSCC patients in China.

    Authors: Chunyan Hu, Huatao Quan, Li Yan, Ji Sun, Lin Lan and Shengzi Wang
    Citation: Infectious Agents and Cancer 2020 15:36
  17. Hepatitis C virus (HCV) represents a major risk factor for hepatocellular carcinoma (HCC) development and anti-HCV therapy is a significant measure to reduce the incidence of HCC, however development of HCC in...

    Authors: Javeria Khalid, Mohammad Umar, Tofeeq Ur-Rehman, Mashhood Ali and Gul Majid Khan
    Citation: Infectious Agents and Cancer 2020 15:35
  18. To investigate high-risk HPV (hr-HPV) genotype distributions and the association between hr-HPV infection with severity of the cervical lesions in women with normal cytology.

    Authors: Zhiling Wang, Ting Liu, Yunjian Wang, Ying Gu, Hui Wang, Jingkang Liu, Baoxia Cui and Xingsheng Yang
    Citation: Infectious Agents and Cancer 2020 15:34
  19. There has been limited research on the comparison of squamous cell carcinoma (SCC) and adenocarcinoma (AC) of cervical cancer and that lack of information may have significant bearing on the treatment of patie...

    Authors: Tian Tian, Xing Gong, Xudong Gao, Yanqing Li, Wen Ju and Yiqin Ai
    Citation: Infectious Agents and Cancer 2020 15:33
  20. Viral infections can reduce early cancer development through enhancement of cancer immunosurveillance. This study was performed to analyse this effect of viral infection in a mouse model of solid tumor.

    Authors: Mohamed F. Mandour, Pyone Pyone Soe, Catherine Uyttenhove, Jacques Van Snick, Etienne Marbaix and Jean-Paul Coutelier
    Citation: Infectious Agents and Cancer 2020 15:30
  21. The detection of the Epstein–Barr capsid antigen (VCA) immunoglobulin A (IgA) is widely used in the diagnosis of nasopharyngeal carcinoma (NPC), but a reference standard for evaluating the presence of VCA-IgA ...

    Authors: Hao Chen, Qiaohua Zhong, Xiaobin Wu, Yanling Ding, Qi Chen, Ning Xue, Yiwei Xu and Shulin Chen
    Citation: Infectious Agents and Cancer 2020 15:25
  22. The cause of epithelial ovarian cancer (EOC) is not elucidated. Viral infection may induce chronic inflammatory infection and play a role in the pathogenesis of cancers. Some viruses are considered to be oncom...

    Authors: Min Yin, Aiping Chen, Fei Zhao, Xuechao Ji, Chuan Li and Guangning Wang
    Citation: Infectious Agents and Cancer 2020 15:23
  23. Infection with human papillomaviruses (HPVs) can cause benign and malignant tumours in the anogenital tract and the oropharynx both in men and women. The aim of the presented study was to investigate cervical,...

    Authors: Maria Nasioutziki, Kimon Chatzistamatiou, Panagiotis-Dimitrios Loufopoulos, Eleftherios Vavoulidis, Nikolaos Tsampazis, George-Chrysostomos Pratilas, Anastasios Liberis, Vasiliki Karpa, Evanggelos Parcharidis, Angelos Daniilidis, Konstantinos Spanos and Konstantinos Dinas
    Citation: Infectious Agents and Cancer 2020 15:22
  24. Hepatocellular carcinoma is a primary liver malignancy in which the risk of development is always multifunctional. Interleukin-6 is a proinflammatory and multifunctional cytokine, which plays an important role...

    Authors: Faisal Adnan, Najeeb Ullah Khan, Aqib Iqbal, Ijaz Ali, Arnolfo Petruzziello, Rocco Sabatino, Annunziata Guzzo, Giovanna Loquercio, Gerardo Botti, Sanaullah Khan, Muhammad Naeem and Muhammad Ismail Khan
    Citation: Infectious Agents and Cancer 2020 15:21
  25. Vulvar squamous cell carcinoma (VSCC) is a rare malignancy of the female genital tract. We aimed to determine the mucosal high-risk human papillomavirus (HPV)-attributable fraction of VSCCs from Italian women ...

    Authors: Mario Preti, John Charles Rotondo, Dana Holzinger, Leonardo Micheletti, Niccolò Gallio, Sandrine McKay-Chopin, Christine Carreira, Sebastiana Silvana Privitera, Reiko Watanabe, Ruediger Ridder, Michael Pawlita, Chiara Benedetto, Massimo Tommasino and Tarik Gheit
    Citation: Infectious Agents and Cancer 2020 15:20
  26. Persistence of human papillomavirus (HPV) infections is associated with squamous cell carcinomas of different human anatomic sites. Several studies have suggested a potential role for HPV infection, particular...

    Authors: Sandra F. Martins, Vânia Mariano, Mesquita Rodrigues and Adhemar Longatto-Filho
    Citation: Infectious Agents and Cancer 2020 15:17
  27. Cervical cancer is the most common malignancy of the female lower genital tract. In our previous study, we found that TLR4 promotes cervical cancer cell growth in vitro. The aim of this study was to further ex...

    Authors: Ninghong Jiang, Feng Xie, Limei Chen, Fang Chen and Long Sui
    Citation: Infectious Agents and Cancer 2020 15:12
  28. The efficacy of cervical cancer screening programs is dependent on the participation rate. To increase participation among women not attending cervical cancer screening, self-collected samples for detection of...

    Authors: Avalon Ernstson, Annika Urdell, Ola Forslund and Christer Borgfeldt
    Citation: Infectious Agents and Cancer 2020 15:10
  29. Cervical cancer is the fourth most common malignant tumor in women worldwide. The persistent infection of high-risk Human Papillomavirus (hrHPV) is considered to be the primary cause of this disease. As an inn...

    Authors: Xubin Liu, Hanyu Ma, Lingyan Fei, Mengjie Jiang, Meng Xia, Lihong Bai, Xufang Pi, Shangwu Chen and Li Yu
    Citation: Infectious Agents and Cancer 2020 15:6
  30. Co-existence of hepatocellular carcinoma (HCC) and cystic echinococcus (CE) is extremely rare. Echinococcus granulosus may exhibit a protective effect against cancer. Herein, this study aimed to evaluate the poss...

    Authors: Ran Bo, Aimaiti Yasen, Yingmei Shao, Wenbao Zhang, Renyong Lin, Tiemin Jiang, Hao Wen, Hui Xiao and Tuerganaili Aji
    Citation: Infectious Agents and Cancer 2020 15:5
  31. Triple-Negative Breast Cancer (TNBC), represents a subtype of breast cancer in which the estrogens receptor (ER) negative, the progesterone receptor (PR) negative and the human epidermal growth factor receptor...

    Authors: Sabrina Bimonte, Marco Cascella, Antonio Barbieri, Claudio Arra and Arturo Cuomo
    Citation: Infectious Agents and Cancer 2020 15:2
  32. Given the paucity of data and widely variable rates that have been reported, the main objective of this study was to examine the prevalence of HPV-positivity in oropharyngeal squamous cell carcinoma (OPSCC) in...

    Authors: Christopher A. Maroun, Karine Al Feghali, Henri Traboulsi, Helene Dabbous, Fatmeh Abbas, Gabriel Dunya, Georges Ziade, Rami Mahfouz, Bassem Youssef, Hani Tamim, Fady Geara, Ibrahim Khalifeh and Roger V. Moukarbel
    Citation: Infectious Agents and Cancer 2020 15:1
  33. The aim of this study was to investigate the prognostic significance of the serum γ-glutamyltransferase (γ-GT)-to-prealbumin ratio (GPR) and whether combining this ratio with other parameters can lead to an im...

    Authors: Q. Wang, P. Zhao, N. He, J. P. Sun, K. Li, C. R. Zang, Y. N. Zhao, Y. Zhao and Y. H. Zhang
    Citation: Infectious Agents and Cancer 2019 14:49
  34. Earlier we suggested a new hypothesis of the possible evolutionary role of hereditary tumors (Kozlov, Evolution by tumor Neofunctionalization, 2014), and described a new class of genes – tumor specifically exp...

    Authors: E. A. Matyunina, A. V. Emelyanov, T. V. Kurbatova, A. A. Makashov, I. V. Mizgirev and A. P. Kozlov
    Citation: Infectious Agents and Cancer 2019 14:46

    The Correction to this article has been published in Infectious Agents and Cancer 2020 15:3

  35. Although the Kaposi sarcoma (KS) is one of the AIDS defining entity and seen in almost one third of HIV infected patients with low CD4 cell counts, it is not uncommon in HIV seronegative persons, but genital K...

    Authors: Abdulaziz Alamri and B. K. Adiga
    Citation: Infectious Agents and Cancer 2019 14:45
  36. Infections classified as group 1 biological carcinogens include the helminthiases caused by Schistosoma haematobium and Opisthorchis viverrini. The molecular mediators underlying the infection with these parasite...

    Authors: Maria João Gouveia, Paul J. Brindley, Gabriel Rinaldi, Fátima Gärtner, José M. C. da Costa and Nuno Vale
    Citation: Infectious Agents and Cancer 2019 14:41
  37. To compare liver-specific EOB-GD-DTPA and liver-non-specific Gd-BT-DO3A MR, in hepatocellular carcinoma (HCC) and liver colorectal metastases.

    Authors: Vincenza Granata, Roberta Fusco, Francesca Maio, Antonio Avallone, Guglielmo Nasti, Raffaele Palaia, Vittorio Albino, Roberto Grassi, Francesco Izzo and Antonella Petrillo
    Citation: Infectious Agents and Cancer 2019 14:40
  38. Persistent infection with human papillomaviruses (HPVs) has been associated with cervical intraepithelial neoplasia (CIN) and cervical cancer. However, why only a fraction of HPV cases progress to cancer is st...

    Authors: Junwei Zhao, Qin Zhan, Junhan Guo, Min Liu, Yetian Ruan, Tailin Zhu, Lingfei Han and Fang Li
    Citation: Infectious Agents and Cancer 2019 14:38
  39. It has been reported that lncRNA MAGI2-AS3 can promote many types of cancer, such as breast cancer and bladder cancer, by regulating cell behaviors, such a proliferation, invasion, and migration. However, its ...

    Authors: Qifang Liu, Shuang Liu, Xiaoying Wang, Jin Zhang and Kuiran Liu
    Citation: Infectious Agents and Cancer 2019 14:37
  40. Hepatitis B caused by HBV is a serious public health hazard prevalent worldwide including Bangladesh. Few scattered molecular studies of HBV have been reported in Bangladesh. This study aimed to analyze the ge...

    Authors: Md. Golzar Hossain and Keiji Ueda
    Citation: Infectious Agents and Cancer 2019 14:33

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