This study estimated genital warts prevalence, genital-warts-related healthcare resource use and costs, and self-reported human-papillomavirus-related psychosocial impact among male and female patients aged 18...
Authors: Lani Buenconsejo, Smita Kothari-Talwar, Karen Yee, Amit Kulkarni, Nuria Lara, Montserrat Roset, Anna R. Giuliano and Suzanne Garland
Polyomavirus hominis1, also called BK virus (BKV) is a well-known etiological agent of renal transplant nephropathy and cystitis. Recently, it got great attention from the researcher as a principal predisposing f...
Authors: Babbiker Mohammed Taher Gorish, Mohammed Elfatih Hussein Ournasseir and Iman Mohammed Shammat
AIDS-related Kaposi sarcoma (AIDS-KS), a common malignancy in Kenya is associated with high morbidity and mortality. AIDS-KS is treated using bleomycin and vincristine (BV) plus or minus doxorubicin in most lo...
Authors: Naftali Busakhala, Gabriel Kigen, Paul Waako, R. Matthew Strother, Fredrick Chite and Patrick Loehrer Sr
Bacterial infection may be involved in the entire process of tissue carcinogenesis by directly or indirectly affecting the occurrence and development of tumors. Porphyromonas gingivalis (P.gingivalis) is an impor...
Authors: Xiao-bo Liu, Zi-ye Gao, Chuan-tao Sun, Hui Wen, Bo Gao, Sheng-bao Li and Qiang Tong
Human Papilloma Virus (HPV) genotypes concordance among sexual couples has been evaluated in many investigations with considerable variations in the concordance. However, no such study has carried out between ...
Authors: Mehrdad Davarmanesh, Mehrouz Dezfulian, Mohammad Javad Gharavi, Sarang Younesi, Pourandokht Saadati, Mohammad Mehdi Taheri Amin and Seyed Mohammad Jazayeri
Platelet-rich-plasma (PRP) is largely used, thanks to its properties, as wound therapy after surgical resection. Several studies and clinical findings have demonstrated that the PRP can accelerate the regenera...
Authors: Antonio Barbieri, Sabrina Bimonte, Giovanna Loquercio, Domenica Rea, Marco Cascella, Annamaria Anniciello, Antonio Luciano, Giuseppe Palma, Gaetano Di Costanzo, Azzaro Rosa, Pasquale Giuliano and Claudio Arra
B7-H4 is among the B7 family members which may serve as a new targetable immune checkpoint molecule. It was reported that high level of serum B7-H4 level may be correlated with lymphoma. Nevertheless, the role...
Authors: Ying Jiang, Gangli Cai, Jun Lin, Jing Zhang, Zhilei Bo, Ying Li, Chun Wang and Yin Tong
Ethiopia lies in the high-risk corridor of esophageal squamous cell carcinoma in East Africa, where individuals with this malignancy often do not report established risk factors, suggesting unidentified etiolo...
Authors: Maria E. Leon, Endale Kassa, Abate Bane, Tufa Gemechu, Yared Tilahun, Nigatu Endalafer, Sandrine McKay-Chopin, Rosario N. Brancaccio, Gilles Ferro, Mathewos Assefa, Elizabeth Ward, Massimo Tommasino, Abraham Aseffa, Joachim Schüz, Ahmedin Jemal and Tarik Gheit
The pathogenesis of lung cancer is triggered by a combination of genetic and environmental factors, being the tobacco smoke the most important risk factor. Nevertheless, the incidence of lung cancer in non-smo...
Authors: Estela Maria Silva, Vânia Sammartino Mariano, Paula Roberta Aguiar Pastrez, Miguel Cordoba Pinto, Emily Montosa Nunes, Laura Sichero, Luisa Lina Villa, Cristovam Scapulatempo-Neto, Kari Juhani Syrjanen and Adhemar Longatto-Filho
Burkitt lymphoma (BL) is a relatively common cancer of childhood in tropical Africa, although its precise incidence and continent-wide geographic distribution have not been previously systematically studied.
Authors: Lucia Hämmerl, Murielle Colombet, Rosemary Rochford, David Martin Ogwang and Donald Maxwell Parkin
Cervical cancer is a common cancer among women worldwide and is closely related to high-risk human papillomavirus infection (HR-HPV). The immune microenvironment is thought to play an essential role in viral i...
Authors: Bohan Li, Ling Zhang, Jianguo Zhao, Guichun Tan, Wenwen Zhang, Na Zhang, Jing Tian and Pengpeng Qu
There is a widely held view that a major cause of delay in diagnosis of cancer at an early stage in Africa is the fact that many patients consult traditional healers first and are often treated by them until c...
Authors: C. C. Asuzu, E. O. Akin-Odanye, M. C. Asuzu and J. Holland
While the burden of cancer in Africa is rapidly rising, there is a lack of investment in healthcare professionals to deliver care. Here we report the results of a survey of systemic therapy workload of oncolog...
Authors: Verna Vanderpuye, Nazik Hammad, Yehoda Martei, Wilma M. Hopman, Adam Fundytus, Richard Sullivan, Bostjan Seruga, Gilberto Lopes, Manju Sengar, Michael D. Brundage and Christopher M. Booth
New strategies are needed to combat the high incidence of cervical cancer in resource-limited settings such as sub-Saharan Africa. Screening for high-risk human papillomavirus (hrHPV) DNA is sensitive for pre-...
Authors: Miriam Nakalembe, Philippa Makanga, Frank Mubiru, Megan Swanson, Jeffrey Martin and Megan Huchko
The impact of South Africa’s high human immunodeficiency virus (HIV) burden on cancer risk is not fully understood, particularly in the context of antiretroviral treatment (ART) availability. We examined natio...
Authors: Tafadzwa Dhokotera, Julia Bohlius, Adrian Spoerri, Matthias Egger, Jabulani Ncayiyana, Victor Olago, Elvira Singh and Mazvita Sengayi
Thymoquinone (TQ) is the principal active monomer isolated from the seed of the medicinal plant Nigella sativa. This compound has antitumor effects against various types of cancer including hepatocellular carcino...
Authors: Sabrina Bimonte, Vittorio Albino, Antonio Barbieri, Maria Luisa Tamma, Aurelio Nasto, Raffaele Palaia, Carlo Molino, Paolo Bianco, Andrea Vitale, Rita Schiano, Aldo Giudice and Marco Cascella
We carried out a retrospective study on the prevalence of HPV and genotype distribution by nested PCR and nucleotide sequencing analysis, in formalin-fixed, paraffin-embedded biopsies of 135 head and neck canc...
Authors: Boniface Kofi, Christian Diamant Mossoro-Kpinde, Ralph-Sydney Mboumba Bouassa, Hélène Péré, Leman Robin, Gérard Gresenguet and Laurent Bélec
Oropharyngeal cancers associated with high-risk type human papillomavirus (HR-HPV) infection have better prognosis than virus negative cancers. Similarly, the HPV status in laryngeal cancer (LC) may be associa...
The underlying cause of epithelial ovarian cancer (EOC) is unknown. It has been theorized that infectious agents could contribute to ovarian tumorigenesis.
Authors: Kasper Ingerslev, Estrid Høgdall, Wojciech Skovrider-Ruminski, Tine Henrichsen Schnack, Marianne Lidang, Claus Høgdall and Jan Blaakaer
Portuguese-speaking countries in Africa include Angola, Mozambique, Guinea-Bissau, Cape Verde, São Tomé and Principe. These countries belong to an interstate organization known as PALOP. In June 2018, PALOP or...
Authors: Lúcio Lara Santos, Hirondina Borges Spencer, Fernando Miguel, Satish Tulsidás, Belmira Rodrigues and Lygia Vieira Lopes
With few exceptions, current chemotherapy and radiotherapy protocols only obtain a slightly prolonged survival with severe adverse effects in patients with advanced solid tumors. In particular, most solid mali...
Authors: Alberto Reale, Adriana Vitiello, Valeria Conciatori, Cristina Parolin, Arianna Calistri and Giorgio Palù
Helicobacter pylori infection is associated with the incidence of gastric cancer. Endoscopic resection has been developed as a proper technique to treat early stage of gastric cancer. However, some patients devel...
Authors: Mayu Sato, Kou Miura, Chihiro Kageyama, Hiroyuki Sakae, Yuka Obayashi, Yoshiro Kawahara, Osamu Matsushita, Kenji Yokota and Hiroyuki Okada
Tannerella forsythia and Porphyromonas gingivalis are anaerobic, Gram-negative bacterial species which have been implicated in periodontal diseases as a part of red complex of periodontal pathogens. Esophageal ca...
Authors: Bartosz Malinowski, Anna Węsierska, Klaudia Zalewska, Maya M. Sokołowska, Wiktor Bursiewicz, Maciej Socha, Mateusz Ozorowski, Katarzyna Pawlak-Osińska and Michał Wiciński
Chronic hepatitis B virus (HBV) infection is a major risk factor for the occurrence and development of cirrhosis and hepatocellular carcinoma (HCC). Microvascular invasion (MVI) of HCC is closely related to po...
Authors: Chao Qu, Xinyu Huang, Kui Liu, Kun Li, Bin Tan, Linlin Qu, Jingyu Cao and Chengzhan Zhu
Chronic diseases such as chagasic megaesophagus (secondary to Chagas’ disease) have been suggested as etiological factors for esophageal squamous cell carcinoma; however, the molecular mechanisms involved are ...
Authors: Fernanda Franco Munari, Adriana Cruvinel-Carloni, Croider Franco Lacerda, Antônio Talvane Torres de Oliveira, Cristovam Scapulatempo-Neto, Sandra Regina Morini da Silva, Eduardo Crema, Sheila Jorge Adad, Maria Aparecida Marchesan Rodrigues, Maria Aparecida Coelho Arruda Henry, Denise Peixoto Guimarães, Adhemar Longatto-Filho and Rui Manuel Reis
