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  1. Content type: Review

    Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date. Some of the...

    Authors: Jorge Levican, Mónica Acevedo, Oscar León, Aldo Gaggero and Francisco Aguayo

    Citation: Infectious Agents and Cancer 2018 13:12

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  2. Content type: Research Article

    The role of Fusobacterium nucleatum Fap2 protein in the development of colorectal cancer has recently been explained. Fap2, when bound to the human inhibitory receptor, TIGIT, inhibits the cytotoxic activity of n...

    Authors: Leonardo A. Guevarra Jr, Andrea Claudine F. Afable, Patricia Joyce O. Belza, Karen Joy S. Dy, Scott Justin Q. Lee, Teresa T. Sy-Ortin and Pia Marie S. P. Albano

    Citation: Infectious Agents and Cancer 2018 13:11

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  3. Content type: Review

    Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and accounts for about 6% of all new cancers diagnosed worldwide. Moreover, it is the third and the fifth leading cause of death from ...

    Authors: A. Petrizzo, A. Mauriello, M. L. Tornesello, F. M. Buonaguro, M. Tagliamonte and L. Buonaguro

    Citation: Infectious Agents and Cancer 2018 13:10

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  4. Content type: Research Article

    Despite the increasing incidence of laryngeal squamous cell carcinoma (LSCC) in Algeria, scarce information is available on the importance of the preventable etiological factors which may drive the disease. Re...

    Authors: Nora Kariche, Montserrat Torres Hortal, Samir Benyahia, Laia Alemany, Nabila Moulaï, Omar Clavero, Marleny Muñoz, Wahiba Ouahioune, Djamel Djennaoui, Chafia Touil-Boukoffa, Silvia de Sanjosé and Mehdi Bourouba

    Citation: Infectious Agents and Cancer 2018 13:8

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  5. Content type: Research Article

    Hepatocellular carcinoma (HCC) can develop in patients who are negative for the hepatitis B surface antigen (HBsAg) in serum but positive for hepatitis B virus (HBV) DNA in the liver, referred to as occult HBV...

    Authors: Yuri Hatazawa, Yoshihiko Yano, Rina Okada, Toshihito Tanahashi, Hiroki Hayashi, Hirotaka Hirano, Akihiro Minami, Yuki Kawano, Motofumi Tanaka, Takumi Fukumoto, Yoshiki Murakami, Masaru Yoshida and Yoshitake Hayashi

    Citation: Infectious Agents and Cancer 2018 13:7

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  6. Content type: Research Article

    Persistent infection with High Risk Human Papillomavirus (HR HPV) types plays a major role in the development of cervical cancer. Therefore, the detection of HR HPV types is an essential part of cervical cance...

    Authors: Farzane Jamdar, Farah Farzaneh, Fariba Navidpour, Sarang Younesi, Payam Balvayeh, Maryamsadat Hosseini and Robabeh Ghodssi-Ghasemabadi

    Citation: Infectious Agents and Cancer 2018 13:6

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  7. Content type: Research Article

    Kaposi’s sarcoma (KS) is a common HIV-associated malignancy associated with disability, pain and poor outcomes. The cornerstone of its treatment is antiretroviral therapy, but advanced disease necessitates the...

    Authors: Vini Fardhdiani, Lucas Molfino, Ana Gabriela Zamudio, Rolanda Manuel, Gilda Luciano, Iza Ciglenecki, Barbara Rusch, Laurence Toutous Trellu and Matthew E Coldiron

    Citation: Infectious Agents and Cancer 2018 13:5

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  8. Content type: Research Article

    Cervical cancer (CC) is the leading cause of morbidity and mortality from cancer in Nepalese women. Nearly all cases of CC are caused by infection with certain genotypes of human papillomavirus (HPV). Data on ...

    Authors: Sunil Kumar Sah, Joaquin V. González, Sadina Shrestha, Anurag Adhikari, Krishna Das Manandhar, Shyam Babu Yadav, David A. Stein, Birendra Prasad Gupta and María Alejandra Picconi

    Citation: Infectious Agents and Cancer 2018 13:4

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  9. Content type: Review

    Meat is a crucial nutrient for human health since it represents a giant supply of proteins, minerals, and vitamins. On the opposite hand, the intake of red and processed meat is taken into account dangerous du...

    Authors: Marco Cascella, Sabrina Bimonte, Antonio Barbieri, Vitale Del Vecchio, Domenico Caliendo, Vincenzo Schiavone, Roberta Fusco, Vincenza Granata, Claudio Arra and Arturo Cuomo

    Citation: Infectious Agents and Cancer 2018 13:3

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  10. Content type: Research Article

    Human papillomavirus (HPV) is an important etiologic factor in different cancers of anogenital region and also in a fraction of head and neck cancers (HNC) particularly oropharyngeal tumors. The HPV16 genotype...

    Authors: Dauren Adilbay, Galim Adilbayev, Gulzhan Kidirbayeva, Viktoria Shipilova, Zhanat Sadyk, Gulsum Koyanbekova, Ekaterina Sokolenko and Jan Klozar

    Citation: Infectious Agents and Cancer 2018 13:2

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  11. Content type: Research Article

    The oncogenic potential of Epstein-Barr virus (EBV) in breast cancer is being increasingly recognized. Despite some controversies regarding such role, new evidence is suggesting a culpability of EBV in breast ...

    Authors: Ghimja Fessahaye, Ahmed M. Elhassan, Elwaleed M. Elamin, Ameera A. M. Adam, Anghesom Ghebremedhin and Muntaser E. Ibrahim

    Citation: Infectious Agents and Cancer 2017 12:62

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  12. Content type: Research Article

    Women infected with Human Immune Deficiency Virus (HIV) are assumed to be at higher risk of developing Cervical Cancer (CC). This is due to a rapid progression of pre-invasive to invasive lesions. However, evi...

    Authors: Muluken Gizaw, Adamu Addissie, Sefonias Getachew, Wondimu Ayele, Israel Mitiku, Ulrike Moelle, Tigist Yusuf, Mathias Begoihn, Mathewos Assefa, Ahmedin Jemal and Eva Johanna Kantelhardt

    Citation: Infectious Agents and Cancer 2017 12:61

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  13. Content type: Research Article

    Breast cancer is a leading cause of morbidity and deaths among women worldwide. In Tanzania there is no published data on human epidermal growth receptor-2 (HER2/neu) expression in breast carcinoma. Hormonal r...

    Authors: Amos Rodger Mwakigonja, Nyanda Elias Lushina and Ally Mwanga

    Citation: Infectious Agents and Cancer 2017 12:60

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  14. Content type: Review

    Oesophageal carcinoma (OC) is highly prevalent in Western Kenya especially among the members of the Kalenjin community who reside in the Northern and Southern areas of the Rift Valley. Previous authors have su...

    Authors: Gabriel Kigen, Naftali Busakhala, Zipporah Kamuren, Hillary Rono, Wilfred Kimalat and Evangeline Njiru

    Citation: Infectious Agents and Cancer 2017 12:59

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  15. Content type: Research Article

    Following the well-established relationship between human papillomavirus (HPV) and cervical carcinoma, the carcinogenicity of this virus has also been confirmed in subsets of head and neck carcinoma (HNCA), bu...

    Authors: Warut Pongsapich, Nitathip Eakkasem, Sontana Siritantikorn, Paveena Pithuksurachai, Kshidej Bongsabhikul and Cheerasook Chongkolwatana

    Citation: Infectious Agents and Cancer 2017 12:58

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  16. Content type: Review

    Literature data suggest that multi-parametric Magnetic Resonance Imaging (MRI), including morphologic T2-weigthed images (T2-MRI) and functional approaches such as Dynamic Contrast Enhanced-MRI (DCE-MRI), Diff...

    Authors: Roberta Fusco, Mario Sansone, Vincenza Granata, Sergio Venanzio Setola and Antonella Petrillo

    Citation: Infectious Agents and Cancer 2017 12:57

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  17. Content type: Research Article

    Processes and mechanisms responsible for systemic immune suppression in early-stage cervical cancer remain substantially underinvestigated. In this work, we focused on studying the frequencies of circulating r...

    Authors: Olga V. Kurmyshkina, Pavel I. Kovchur, Ludmila V. Schegoleva and Tatyana O. Volkova

    Citation: Infectious Agents and Cancer 2017 12:56

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  18. Content type: Research Article

    Multiple oncogenic viruses including, mouse mammary tumor virus, bovine leukemia virus, human papilloma virus, and Epstein Barr virus, have been identified as separate infectious pathogens in human breast canc...

    Authors: James S. Lawson and Wendy K. Glenn

    Citation: Infectious Agents and Cancer 2017 12:55

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  19. Content type: Research Article

    Esophageal squamous cell carcinoma (ESCC) is a highly lethal malignant tumor. Currently, Human papillomavirus (HPV) is suggested as a potential risk factor for esophageal cancer (EC) in addition to the classic...

    Authors: Allini Mafra da Costa, José Humberto Tavares Guerreiro Fregnani, Paula Roberta Aguiar Pastrez, Vânia Sammartino Mariano, Estela Maria Silva, Cristovam Scapulatempo Neto, Denise Peixoto Guimarães, Luisa Lina Villa, Laura Sichero, Kari Juhani Syrjanen and Adhemar Longatto-Filho

    Citation: Infectious Agents and Cancer 2017 12:54

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  20. Content type: Research Article

    Esophageal carcinoma (EC) is one of the major cancers in China. In 1982, Syrjanen first hypothesized the relationship between human papillomavirus (HPV) infection and the development of esophageal cancer. Sinc...

    Authors: Shuying Li, Haie Shen, Zhanjun Liu, Ning Li, Suxian Yang, Ke Zhang and Jintao Li

    Citation: Infectious Agents and Cancer 2017 12:53

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  21. Content type: Research article

    Hepatocellular carcinoma (HCC) is one of the major cause for cancer in the world. Aim of this case-control study was to investigate the distribution pattern of HCV genotypes among HCC patients and suggest whet...

    Authors: Arnolfo Petruzziello, Samantha Marigliano, Giovanna Loquercio, Nicola Coppola, Mauro Piccirillo, Maddalena Leongito, Rosa Azzaro, Francesco Izzo and Gerardo Botti

    Citation: Infectious Agents and Cancer 2017 12:52

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  22. Content type: Research Article

    Cervical cancer is the fourth most common cancer in women worldwide with highest incidence reported in Eastern Africa in 2012. The primary goal of this study was to study the expression of p16INK4a in squamous ce...

    Authors: Hina Sarwath, Devendra Bansal, Nazik Elmalaika Husain, Mahmoud Mohamed, Ali A. Sultan and Shahinaz Bedri

    Citation: Infectious Agents and Cancer 2017 12:50

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  23. Content type: Research Article

    The introduction of cART has changed the morbidity and mortality patterns affecting HIV-infected (HIV+) individuals. The risk of breast cancer in HIV+ patients has now approached the general population risk. Howe...

    Authors: Francesca Caccuri, Francesca Giordano, Ines Barone, Pietro Mazzuca, Cinzia Giagulli, Sebastiano Andò, Arnaldo Caruso and Stefania Marsico

    Citation: Infectious Agents and Cancer 2017 12:49

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  24. Content type: Research Article

    Direct-acting antivirals have been used for decompensated cirrhotic patients with hepatitis C virus (HCV) infection. However, the benefits in Chinese patients with decompensated cirrhosis are unclear.

    Authors: Fanpu Ji, Wenjun Wang, Shuangsuo Dang, Shengbang Wang, Burong Li, Dan Bai, Wenxue Zhao, Hong Deng, Changyin Tian and Zongfang Li

    Citation: Infectious Agents and Cancer 2017 12:48

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  25. Content type: Research Article

    To evaluate the diagnostic efficacy of prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) for early stage hepatitis virus B (HBV) related hepatocellular carcinoma (HCC).

    Authors: Xiumei Wang, Weiwei Zhang, Youde Liu, Wenjing Gong, Ping Sun, Xiangshuo Kong, Miaomiao Yang and Zhihua Wang

    Citation: Infectious Agents and Cancer 2017 12:47

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  26. Content type: Research Article

    Although high risk HPVs are associated with an increased risk of prostate cancer it is not known if they have a causal role. The purpose of this study is to investigate the potential role of human papilloma vi...

    Authors: Wendy K. Glenn, Christopher C. Ngan, Timothy G. Amos, Richard J. Edwards, Joshua Swift, Louise Lutze-Mann, Fei Shang, Noel J. Whitaker and James S. Lawson

    Citation: Infectious Agents and Cancer 2017 12:46

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  27. Content type: Short Report

    Lymphoma is highly associated with HIV in sub-Saharan Africa (SSA), which contributes to worse outcomes relative to resource-rich settings, and frequent failure of first-line chemotherapy. However, there are n...

    Authors: Bongani Kaimila, Toon van der Gronde, Christopher Stanley, Edwards Kasonkanji, Maria Chikasema, Blessings Tewete, Paula Fox and Satish Gopal

    Citation: Infectious Agents and Cancer 2017 12:45

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  28. Content type: Research Article

    Human papillomavirus genotypes 52 and 58 (HPV52/58) are frequently detected in patients with cervical intraepithelial neoplasia (CIN) and invasive cervical cancer (ICC) in East Asian countries including Japan....

    Authors: Yuri Tenjimbayashi, Mamiko Onuki, Yusuke Hirose, Seiichiro Mori, Yoshiyuki Ishii, Takamasa Takeuchi, Nobutaka Tasaka, Toyomi Satoh, Tohru Morisada, Takashi Iwata, Shingo Miyamoto, Koji Matsumoto, Akihiko Sekizawa and Iwao Kukimoto

    Citation: Infectious Agents and Cancer 2017 12:44

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  29. Content type: Research Article

    Although analysis of the Human papillomavirus (HPV) genotype spread in a particular area has a crucial impact on public health and prevention programmes, there is a lack of epidemiological data regarding HPV i...

    Authors: Luisa Galati, Cinzia Peronace, Maria Teresa Fiorillo, Rosanna Masciari, Cristina Giraldi, Salvatore Nisticò, Pasquale Minchella, Vincenzo Maiolo, Giorgio Settimo Barreca, Nadia Marascio, Angelo Giuseppe Lamberti, Aida Giancotti, Maria Gabriella Lepore, Francesca Greco, Maria Vittoria Mauro, Annelisa Borelli…

    Citation: Infectious Agents and Cancer 2017 12:43

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  30. Content type: Research Article

    The role of interleukin (IL) 17A in chronic liver diseases had been extensively studied, but the function of IL-17F, which shares a high degree of homology with IL-17A, in the progression of chronic hepatic di...

    Authors: Ming-Sian Wu, Chun-Hsiang Wang, Fan-Chen Tseng, Hsuan-Ju Yang, Yin-Chiu Lo, Yi-Ping Kuo, De-Jiun Tsai, Wan-Ting Tsai and Guann-Yi Yu

    Citation: Infectious Agents and Cancer 2017 12:42

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  31. Content type: Research Article

    Gastric cancer (GC) is one of the most common malignant tumors of the digestive tract and is the third leading cause of cancer death worldwide. Epstein–Barr virus (EBV) has been associated with approximately 1...

    Authors: Célia Nogueira, Marta Mota, Rui Gradiz, Maria Augusta Cipriano, Francisco Caramelo, Hugo Cruz, Ana Alarcão, Francisco Castro e Sousa, Fernando Oliveira, Fernando Martinho, João Moura Pereira, Paulo Figueiredo and Maximino Leitão

    Citation: Infectious Agents and Cancer 2017 12:41

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  32. Content type: Research Article

    In recent years, saprophytic bacteria have been emerging as potential human pathogens causing life-threatening infections in patients with malignancies. However, evidence is lacking concerning such bacteria, p...

    Authors: Balew Arega, Yimtubezinash Wolde-Amanuel, Kelemework Adane, Ezra Belay, Abdulaziz Abubeker and Daniel Asrat

    Citation: Infectious Agents and Cancer 2017 12:40

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  33. Content type: Research Article

    The role of human cytomegalovirus (HCMV) in the development of breast carcinoma is questionable. The aim of this study was to evaluate the expression of the immediate early antigen (IE) of HCMV in breast carci...

    Authors: Fereshteh Mohammadizadeh and Fatemeh Mahmudi

    Citation: Infectious Agents and Cancer 2017 12:39

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  34. Content type: Erratum

    Authors: Olugbenga Akindele Silas, Chad J. Achenbach, Lifang Hou, Robert L. Murphy, Julie O. Egesie, Solomon A. Sagay, Oche O. Agbaji, Patricia A. Agaba, Jonah Musa, Agabus N. Manasseh, Ezra D. Jatau, Ayuba M. Dauda, Maxwell O. Akanbi and Barnabas M. Mandong

    Citation: Infectious Agents and Cancer 2017 12:37

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    The original article was published in Infectious Agents and Cancer 2017 12:34

  35. Content type: Review

    Alzheimer’s disease (AD) is a neurodegenerative disorder and the most common form of dementia characterized by cognitive and memory impairment. One of the mechanism involved in the pathogenesis of AD, is the o...

    Authors: Marco Cascella, Sabrina Bimonte, Maria Rosaria Muzio, Vincenzo Schiavone and Arturo Cuomo

    Citation: Infectious Agents and Cancer 2017 12:36

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  36. Content type: Research Article

    Electrochemotherapy (ECT) has shown to be an effective treatment for cutaneous and subcutaneous Kaposi sarcoma (KS) lesions. However, no study has investigated the impact of ECT treatment on the kinetics of hu...

    Authors: Noemy Starita, Gianluca Di Monta, Andrea Cerasuolo, Ugo Marone, Anna Maria Anniciello, Gerardo Botti, Luigi Buonaguro, Franco M. Buonaguro and Maria Lina Tornesello

    Citation: Infectious Agents and Cancer 2017 12:35

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  37. Content type: Research Article

    Lymphoma is a leading cause of cancer-related death among human immunodeficiency virus (HIV)-infected individuals in the current era of potent anti-retroviral therapy (ART). Globally, mortality after HIV-assoc...

    Authors: Olugbenga Akindele Silas, Chad J. Achenbach, Lifang Hou, Robert L. Murphy, Julie O. Egesie, Solomon A. Sagay, Oche O. Agbaji, Patricia E. Agaba, Jonah Musa, Agabus N. Manasseh, Ezra D. Jatau, Ayuba M. Dauda, Maxwell O. Akanbi and Barnabas M. Mandong

    Citation: Infectious Agents and Cancer 2017 12:34

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    The Erratum to this article has been published in Infectious Agents and Cancer 2017 12:37

  38. Content type: Research Article

    Lithuania remains one of the highest tuberculosis burden countries in Europe. Epidemiological studies have long pointed to infections as important factors of cancer aetiology, but the association between tuber...

    Authors: Ruta Everatt, Irena Kuzmickiene, Edita Davidaviciene and Saulius Cicenas

    Citation: Infectious Agents and Cancer 2017 12:33

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  39. Content type: Short Report

    Little information on the prevalence of Kaposi’s sarcoma associated herpesvirus (KSHV) among HIV-negative individuals is available from Asia.

    Authors: Tiejun Zhang, Zhenqiu Liu, Jun Wang, Veenu Minhas, Charles Wood, Gary M. Clifford, Na He and Silvia Franceschi

    Citation: Infectious Agents and Cancer 2017 12:32

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  40. Content type: Research Article

    The association between Epstein-Barr virus (EBV) and the development of head and neck cancer was reported by many researchers. The aim of the present study was to detect EBV DNA and EBV antibodies in 110 Polis...

    Authors: Sylwia Fołtyn, Małgorzata Strycharz-Dudziak, Bartłomiej Drop, Anastazja Boguszewska and Małgorzata Polz-Dacewicz

    Citation: Infectious Agents and Cancer 2017 12:31

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  41. Content type: Research Article

    Though TRAIL has been hailed as a promising drug for tumour treatment, it has been observed that many tumour cells have developed escape mechanisms against TRAIL-induced apoptosis. As a receptor of LPS, TLR 4,...

    Authors: Katharina Beyer, Lars Ivo Partecke, Felicitas Roetz, Herbert Fluhr, Frank Ulrich Weiss, Claus-Dieter Heidecke and Wolfram von Bernstorff

    Citation: Infectious Agents and Cancer 2017 12:30

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  42. Content type: Research Article

    Sexually transmitted infections (STIs) remain an important public health problem with approximately half a billion new cases annually among persons aged 15–49 years. Epidemiological data on STIs among women of...

    Authors: Themba G. Ginindza, Cristina D. Stefan, Joyce M. Tsoka-Gwegweni, Xolisile Dlamini, Pauline E. Jolly, Elisabete Weiderpass, Nathalie Broutet and Benn Sartorius

    Citation: Infectious Agents and Cancer 2017 12:29

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  43. Content type: Research Article

    The conception that serological hepatitis markers determined surgical prognosis of hepatocellular carcinoma (HCC) associated with hepatitis B (HBV) or hepatitis C (HCV) has been well defined. However, little i...

    Authors: Xiu-Tao Fu, Ying-Hong Shi, Jian Zhou, Yuan-Fei Peng, Wei-Ren Liu, Guo-Ming Shi, Qiang Gao, Xiao-Ying Wang, Kang Song, Jia Fan and Zhen-Bin Ding

    Citation: Infectious Agents and Cancer 2017 12:28

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  44. Content type: Review

    Primary hepatocellular carcinoma (HCC) mainly develops in subjects chronically infected with hepatitis B (HBV) and C (HCV) viruses through a multistep process characterized by the accumulation of genetic alter...

    Authors: Francesca Pezzuto, Luigi Buonaguro, Franco M. Buonaguro and Maria Lina Tornesello

    Citation: Infectious Agents and Cancer 2017 12:27

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  45. Content type: Review

    The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease could play a role in ovarian carcinogenesis.

    Authors: Kasper Ingerslev, Estrid Hogdall, Tine Henrichsen Schnack, Wojciech Skovrider-Ruminski, Claus Hogdall and Jan Blaakaer

    Citation: Infectious Agents and Cancer 2017 12:25

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