Shannon-Lowe C, Rickinson AB, Bell AI. Epstein-Barr virus-associated lymphomas. Philos Trans R Soc Lond B Biol Sci. 2017. https://doi.org/10.1098/rstb.2016.0271.
Article
PubMed
PubMed Central
Google Scholar
Shah KM, Young LS. Epstein-Barr virus and carcinogenesis: beyond Burkitt’s lymphoma. Clin Microbiol Infect. 2009;15(11):982–8.
Article
CAS
PubMed
Google Scholar
Ambrosio MR, Navari M, Di Lisio L, Leon EA, Onnis A, Gazaneo S, et al. The Epstein Barr-encoded BART-6-3p microRNA affects regulation of cell growth and immuno response in Burkitt lymphoma. Infect Agent Cancer. 2014;9:12.
Article
PubMed
PubMed Central
Google Scholar
Cai X, Schäfer A, Lu S, Bilello JP, Desrosiers RC, Edwards R, et al. Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed. PLoS Pathog. 2006;2(3): e23.
Article
PubMed
PubMed Central
Google Scholar
Piccaluga PP, Navari M, De Falco G, Ambrosio MR, Lazzi S, Fuligni F, et al. Virus-encoded microRNA contributes to the molecular profile of EBV-positive Burkitt lymphomas. Oncotarget. 2016;7(1):224–40.
Article
PubMed
Google Scholar
Thorley-Lawson DA. EBV persistence-introducing the virus. Curr Top Microbiol Immunol. 2015;390(Pt 1):151–209.
CAS
PubMed
PubMed Central
Google Scholar
Hatton OL, Harris-Arnold A, Schaffert S, Krams SM, Martinez OM. The interplay between Epstein-Barr virus and B lymphocytes: implications for infection, immunity, and disease. Immunol Res. 2014;58(2–3):268–76.
Article
CAS
PubMed
PubMed Central
Google Scholar
Granai M, Mundo L, Akarca AU, Siciliano MC, Rizvi H, Mancini V, et al. Immune landscape in Burkitt lymphoma reveals M2-macrophage polarization and correlation between PD-L1 expression and non-canonical EBV latency program. Infect Agent Cancer. 2020;15:28.
Article
CAS
PubMed
PubMed Central
Google Scholar
Scott RS. Epstein-Barr virus: a master epigenetic manipulator. Curr Opin Virol. 2017;26:74–80.
Article
CAS
PubMed
PubMed Central
Google Scholar
Vargas-Ayala RC, Jay A, Manara F, Maroui MA, Hernandez-Vargas H, Diederichs A, et al. Interplay between the epigenetic enzyme lysine (K)-specific demethylase 2B and Epstein-Barr virus infection. J Virol. 2019. https://doi.org/10.1128/JVI.00273-19.
Article
PubMed
PubMed Central
Google Scholar
Leonard S, Wei W, Anderton J, Vockerodt M, Rowe M, Murray PG, et al. Epigenetic and transcriptional changes which follow Epstein-Barr virus infection of germinal center B cells and their relevance to the pathogenesis of Hodgkin’s lymphoma. J Virol. 2011;85(18):9568–77.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mundo L, Ambrosio MR, Picciolini M, Lo Bello G, Gazaneo S, Del Porro L, et al. Unveiling another missing piece in EBV-driven lymphomagenesis: EBV-encoded MicroRNAs expression in EBER-negative Burkitt lymphoma cases. Front Microbiol. 2017;8:229.
Article
PubMed
PubMed Central
Google Scholar
Ambinder RF. Gammaherpesviruses and “Hit-and-Run” oncogenesis. Am J Pathol. 2000;156(1):1–3.
Article
CAS
PubMed
PubMed Central
Google Scholar
Birdwell CE, Queen KJ, Kilgore PC, Rollyson P, Trutschl M, Cvek U, et al. Genome-wide DNA methylation as an epigenetic consequence of Epstein-Barr virus infection of immortalized keratinocytes. J Virol. 2014;88(19):11442–58.
Article
PubMed
PubMed Central
Google Scholar
Niller HH, Wolf H, Minarovits J. Viral hit and run-oncogenesis: genetic and epigenetic scenarios. Cancer Lett. 2011;305(2):200–17.
Article
CAS
PubMed
Google Scholar
Queen KJ, Shi M, Zhang F, Cvek U, Scott RS. Epstein-Barr virus-induced epigenetic alterations following transient infection. Int J Cancer. 2013;132(9):2076–86.
Article
CAS
PubMed
Google Scholar
Hutcheson RL, Chakravorty A, Sugden B. Burkitt lymphomas evolve to escape dependencies on Epstein-Barr Virus. Front Cell Infect Microbiol. 2020;10: 606412.
Article
PubMed
Google Scholar
Abate F, Ambrosio MR, Mundo L, Laginestra MA, Fuligni F, Rossi M, et al. Distinct viral and mutational spectrum of endemic Burkitt lymphoma. PLoS Pathog. 2015;11(10): e1005158.
Article
PubMed
PubMed Central
Google Scholar
Vereide D, Sugden B. Proof for EBV’s sustaining role in Burkitt’s lymphomas. Semin Cancer Biol. 2009;19(6):389–93.
Article
PubMed
PubMed Central
Google Scholar
Srinivas SK, Sample JT, Sixbey JW. Spontaneous loss of viral episomes accompanying Epstein-Barr virus reactivation in a Burkitt’s lymphoma cell line. J Infect Dis. 1998;177(6):1705–9.
Article
CAS
PubMed
Google Scholar
Dittmer DP, Hilscher CJ, Gulley ML, Yang EV, Chen M, Glaser R. Multiple pathways for Epstein-Barr virus episome loss from nasopharyngeal carcinoma. Int J Cancer. 2008;123(9):2105–12.
Article
CAS
PubMed
PubMed Central
Google Scholar
Trivedi P, Zhang QJ, Chen F, Minarovits J, Ekman M, Biberfeld P, et al. Parallel existence of Epstein-Barr virus (EBV) positive and negative cells in a sporadic case of Burkitt lymphoma. Oncogene. 1995;11(3):505–10.
CAS
PubMed
Google Scholar
Mundo L, Del Porro L, Granai M, Siciliano MC, Mancini V, Santi R, et al. Frequent traces of EBV infection in Hodgkin and non-Hodgkin lymphomas classified as EBV-negative by routine methods: expanding the landscape of EBV-related lymphomas. Mod Pathol. 2020;33(12):2407–21.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fukayama M. Epstein-Barr virus and gastric carcinoma. Pathol Int. 2010;60(5):337–50.
Article
CAS
PubMed
Google Scholar
Nagtegaal ID, Odze RD, Klimstra D, Paradis V, Rugge M, Schirmacher P, et al. The 2019 WHO classification of tumours of the digestive system. Histopathology. 2020;76(2):182–8.
Article
PubMed
Google Scholar
Network CGAR. Comprehensive molecular characterization of gastric adenocarcinoma. Nature. 2014;513(7517):202–9.
Article
Google Scholar
Saha A, Jha HC, Upadhyay SK, Robertson ES. Epigenetic silencing of tumor suppressor genes during in vitro Epstein-Barr virus infection. Proc Natl Acad Sci U S A. 2015;112(37):E5199–207.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kang GH, Lee S, Cho NY, Gandamihardja T, Long TI, Weisenberger DJ, et al. DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis. Lab Invest. 2008;88(2):161–70.
Article
CAS
PubMed
Google Scholar
Matsusaka K, Kaneda A, Nagae G, Ushiku T, Kikuchi Y, Hino R, et al. Classification of Epstein-Barr virus-positive gastric cancers by definition of DNA methylation epigenotypes. Cancer Res. 2011;71(23):7187–97.
Article
CAS
PubMed
Google Scholar
Ghosh Roy S, Robertson ES, Saha A. Epigenetic impact on EBV associated B-cell lymphomagenesis. Biomolecules. 2016;6(4):46.
Article
PubMed Central
Google Scholar
Kong D, Ma W, Zhang D, Cui Q, Wang K, Tang J, et al. EYA1 promotes cell migration and tumor metastasis in hepatocellular carcinoma. Am J Transl Res. 2019;11(4):2328–38.
CAS
PubMed
PubMed Central
Google Scholar
Wang W, Zhang Y, Liu M, Wang Y, Yang T, Li D, et al. TIMP2 is a poor prognostic factor and predicts metastatic biological behavior in gastric cancer. Sci Rep. 2018;8(1):9629.
Article
PubMed
PubMed Central
Google Scholar
Fukayama M, Kunita A, Kaneda A. Gastritis-infection-cancer sequence of Epstein-Barr virus-associated gastric cancer. Adv Exp Med Biol. 2018;1045:437–57.
Article
CAS
PubMed
Google Scholar
Kusano M, Toyota M, Suzuki H, Akino K, Aoki F, Fujita M, et al. Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus. Cancer. 2006;106(7):1467–79.
Article
CAS
PubMed
Google Scholar
Wang F, Flanagan J, Su N, Wang LC, Bui S, Nielson A, et al. RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues. J Mol Diagn. 2012;14(1):22–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Takakuwa T, Luo WJ, Ham MF, Sakane-Ishikawa F, Wada N, Aozasa K. Integration of Epstein-Barr virus into chromosome 6q15 of Burkitt lymphoma cell line (Raji) induces loss of BACH2 expression. Am J Pathol. 2004;164(3):967–74.
Article
CAS
PubMed
PubMed Central
Google Scholar
Lay ML, Lucas RM, Ratnamohan M, Taylor J, Ponsonby AL, Dwyer DE, et al. Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dye. Virol J. 2010;7:252.
Article
PubMed
PubMed Central
Google Scholar
Camargo MC, Kim WH, Chiaravalli AM, Kim KM, Corvalan AH, Matsuo K, et al. Improved survival of gastric cancer with tumour Epstein-Barr virus positivity: an international pooled analysis. Gut. 2014;63(2):236–43.
Article
PubMed
Google Scholar
Re V, Brisotto G, Repetto O, De Zorzi M, Caggiari L, Zanussi S, et al. Overview of Epstein-Barr-virus-associated gastric cancer correlated with prognostic classification and development of therapeutic options. Int J Mol Sci. 2020. https://doi.org/10.3390/ijms21249400.
Article
PubMed
PubMed Central
Google Scholar
Sanosyan A, Fayd’herbe de Maudave A, Bollore K, Zimmermann V, Foulongne V, Van de Perre P, et al. The impact of targeting repetitive BamHI-W sequences on the sensitivity and precision of EBV DNA quantification. PLoS ONE. 2017;12(8):e0183856.
Article
PubMed
PubMed Central
Google Scholar
Ababneh E, Saad AM, Crane GM. The role of EBV in haematolymphoid proliferations: emerging concepts relevant to diagnosis and treatment. Histopathology. 2021;79(4):451–64.
Article
PubMed
Google Scholar
Jox A, Rohen C, Belge G, Bartnitzke S, Pawlita M, Diehl V, et al. Integration of Epstein-Barr virus in Burkitt’s lymphoma cells leads to a region of enhanced chromosome instability. Ann Oncol. 1997;8(Suppl 2):131–5.
Article
PubMed
Google Scholar
Xu M, Zhang WL, Zhu Q, Zhang S, Yao YY, Xiang T, et al. Genome-wide profiling of Epstein-Barr virus integration by targeted sequencing in Epstein-Barr virus associated malignancies. Theranostics. 2019;9(4):1115–24.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chang Y, Cheng SD, Tsai CH. Chromosomal integration of Epstein-Barr virus genomes in nasopharyngeal carcinoma cells. Head Neck. 2002;24(2):143–50.
Article
PubMed
Google Scholar
Xiao K, Yu Z, Li X, Tang K, Tu C, Qi P, et al. Genome-wide analysis of Epstein-Barr virus (EBV) integration and strain in C666–1 and Raji cells. J Cancer. 2016;7(2):214–24.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chakravorty S, Yan B, Wang C, Wang L, Quaid JT, Lin CF, et al. Integrated pan-cancer map of EBV-associated neoplasms reveals functional host-virus interactions. Cancer Res. 2019;79(23):6010–23.
Article
CAS
PubMed
PubMed Central
Google Scholar
Shinozaki-Ushiku A, Kunita A, Fukayama M. Update on Epstein-Barr virus and gastric cancer (review). Int J Oncol. 2015;46(4):1421–34.
Article
CAS
PubMed
Google Scholar
Tan GW, Visser L, Tan LP, van den Berg A, Diepstra A. The microenvironment in Epstein-Barr Virus-associated malignancies. Pathogens. 2018. https://doi.org/10.3390/pathogens7020040.
Article
PubMed
PubMed Central
Google Scholar
Bauer M, Jasinski-Bergner S, Mandelboim O, Wickenhauser C, Seliger B. Epstein-Barr virus-associated malignancies and immune escape: the role of the tumor microenvironment and tumor cell evasion strategies. Cancers (Basel). 2021. https://doi.org/10.3390/cancers13205189.
Article
PubMed Central
Google Scholar