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  1. Persistent infection with high-risk human papillomavirus (HPV) is a major risk factor for malignant lesions and cervical cancer. A widely studied element in the search for genetic factors influencing risk HPV ...

    Authors: Sofía Bernal-Silva, Julio Granados, Clara Gorodezky, Carmen Aláez, Hilario Flores-Aguilar, Ricardo M Cerda-Flores, Geraldina Guerrero-González, Lezmes D Valdez-Chapa, José Morales-Casas, Juan Francisco González-Guerrero and Hugo A Barrera-Saldaña
    Citation: Infectious Agents and Cancer 2013 8:31
    Content type: Research article Published on:

  2. Nasopharyngeal carcinoma (NPC) accounts for 0.6% of all cancers worldwide with the highest prevalence in South East Asia, Southern China and Northern Africa but the disease is uncommon in Europe with an annual...

    Authors: Max Robinson, Yae-eun Suh, Vinidh Paleri, Debbie Devlin, Bushra Ayaz, Laura Pertl and Selvam Thavaraj
    Citation: Infectious Agents and Cancer 2013 8:30
    Content type: Research article Published on:

  3. Nasopharyngeal carcinoma is a distinct type of head and neck cancer which is consistently associated with Epstein-Barr virus (EBV). The C666-1 cell line is the only in vitro native EBV-infected NPC cell model ...

    Authors: Ken Kai-Yuen Tso, Kevin Yuk-Lap Yip, Cathy Ka-Yan Mak, Grace Tin-Yun Chung, Sau-Dan Lee, Siu-Tim Cheung, Ka-Fai To and Kwok-Wai Lo
    Citation: Infectious Agents and Cancer 2013 8:29
    Content type: Short report Published on:

  4. In HIV-1-infected patients a long lasting CD4+ cell decline influences the host-EBV balance and thereby increases the risk for EBV related malignancies. In spite of a world-wide access to combination antiretro...

    Authors: Anna Friis, Börje Åkerlund, Birger Christensson, Katarina Gyllensten, Anna Aleman, Jie-Zhi Zou and Ingemar Ernberg
    Citation: Infectious Agents and Cancer 2013 8:28
    Content type: Research article Published on:

  5. Although there is significant evidence of a cancer epidemic in Africa, there is limited awareness about cancer in most African countries. By partnering with international organizations and institutions such as...

    Authors: Folakemi T Odedina, Kwanele Asante-Shongwe, Emmanuel J Kandusi, Richard Segal, Shannon Pressey, R Renee Reams and Virgil H Simons
    Citation: Infectious Agents and Cancer 2013 8(Suppl 1):S8
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  6. In this paper, we present six case studies describing innovative cancer advocacy programs in Africa. For each case study, an example of an advocacy activity, list of factors contributing to the success of the ...

    Authors: Folakemi T Odedina and Belmira Rodrigues
    Citation: Infectious Agents and Cancer 2013 8(Suppl 1):S7
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  7. Oftentimes, cancer advocates in Africa look at the developed nations in North America and Europe for guidance on cancer advocacy. However, lessons learnt from developed nations do not necessarily apply to the ...

    Authors: Folakemi T Odedina, Belmira Rodrigues and Priya Raja
    Citation: Infectious Agents and Cancer 2013 8(Suppl 1):S6
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  8. To address the need for a significant increase in cancer advocacy programs in Africa, the University of Florida (UF), the Prostate Net, and the African Organization for Research and Training in Cancer (AORTIC)...

    Authors: R Renee Reams, Folakemi T Odedina and Shannon Pressey
    Citation: Infectious Agents and Cancer 2013 8(Suppl 1):S5
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  9. In making an experience-based case for research advocacy in Africa and suggesting a framework for building it, this paper covers factors such as basic tenets of patient advocacy, key components and urgent need...

    Authors: Mary J Scroggins
    Citation: Infectious Agents and Cancer 2013 8(Suppl 1):S4
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  10. Of all the different types of advocacy, Community Outreach Advocacy (COA) is the best methodology. This methodology is the prolegomena to the achievement of all other advocacies including political, fundraisin...

    Authors: Emmanuel J Kandusi
    Citation: Infectious Agents and Cancer 2013 8(Suppl 1):S3
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  11. The burden of cancer is climbing in all of Africa, yet the continent’s healthcare and political systems have not prioritized cancer control and treatment-care. Sub-Saharan Africa is predicted to have a greater...

    Authors: Kwanele Asante-Shongwe
    Citation: Infectious Agents and Cancer 2013 8(Suppl 1):S2
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  13. The quadrivalent HPV vaccine is highly effective in primary prevention of anogenital warts (AGWs). However, there is lack of systematic review in the literature of the epidemiology of AGWs in Sub Saharan Afric...

    Authors: Cecily Banura, Florence M Mirembe, Jackson Orem, Anthony K Mbonye, Simon Kasasa and Edward K Mbidde
    Citation: Infectious Agents and Cancer 2013 8:27
    Content type: Review Published on:

  15. Certain types of the Human Papillomavirus (HPV) are sexually transmitted and highly associated with development of cervical dysplasia and cervical cancer but the distribution of HPV infection in the North, par...

    Authors: Ying Jiang, Paul Brassard, Alberto Severini, Yang Mao, Y Anita Li, Julie Laroche, Susan Chatwood, Andre Corriveau, Kami Kandola, Brendan Hanley, Isaac Sobol, Muna Ar-Rushdi, Gordon Johnson, Jane Lo, Sam Ratnam, Tom Wong…
    Citation: Infectious Agents and Cancer 2013 8:25
    Content type: Research article Published on:

  16. The present study was designed to determine the possible impact of hepatitis C virus (HCV) infection on the expression of telomerase (TERT), retinoblastoma (RB1), E2F3, TP53, CDKN1A (p21) and fibroblast growth...

    Authors: Kamel Z Hemmaid, Amira Awadalla, Essam Elsawy, Abdel-aziz M Hussein, Azza Abdel-aziz, Ahmed A Shokeir, Ahmed S El-Hefnawy and Hassan Abol-enein
    Citation: Infectious Agents and Cancer 2013 8:24
    Content type: Research article Published on:

  17. Bcr-Abl plays a central role in the development of chromosome positive leukaemia. Chronic Myeloid leukaemia occurs due to increase proliferation and resistance to apoptosis by Bcr-Abl positive cells. Imatinib ...

    Authors: Anum Mughal, Hafiz Muhammad Aslam, Aga Muhammad Hammad Khan, Shafaq Saleem, Ribak Umah and Maria Saleem
    Citation: Infectious Agents and Cancer 2013 8:23
    Content type: Letter to the Editor Published on:

  20. Cervical cancer is the greater cause of cancer death in women in many developing countries. Persistent infection with human papilloma virus (HPV), primarily high risk types 16 and 18, is recognized as a causal...

    Authors: Mohammadreza Haghshenas, Tahereh Golini-moghaddam, Alireza Rafiei, Omid Emadeian, Ahmad Shykhpour and G Hossein Ashrafi
    Citation: Infectious Agents and Cancer 2013 8:20
    Content type: Research Article Published on:

  21. Worldwide, cancers of the urinary bladder are well known to be associated with environmental chemical carcinogens such as smoking and occupational exposure to polycyclic aromatic hydrocarbons. These cancers ar...

    Authors: Peter Fabian Rambau, Philipo L Chalya and Kahima Jackson
    Citation: Infectious Agents and Cancer 2013 8:19
    Content type: Research Article Published on:

  22. In HIV-infected populations in developed countries, the most recent published cancer incidence trend analyses are only updated through 2008. We assessed changes in the distribution of cancer types and incidenc...

    Authors: Elizabeth L Yanik, Kristen Tamburro, Joseph J Eron, Blossom Damania, Sonia Napravnik and Dirk P Dittmer
    Citation: Infectious Agents and Cancer 2013 8:18
    Content type: Research Article Published on:

  23. Lung cancer is an important etiology of malignant mortality worldwide with global statistics indicating over 1 million deaths annually. Although there have been advances in cytotoxic chemotherapy, the prognosi...

    Authors: Syed Hassan Abbas Naqvi, Syed Hassan Shiraz Naqvi, Muhammad Yasin Bandukda and Syed Mumtaz Ali Naqvi
    Citation: Infectious Agents and Cancer 2013 8:17
    Content type: Letter to the Editor Published on:

  27. Exploring the presence and role of human papillomavirus (HPV) in head and neck cancer (HNC) is a necessary step to evaluate the potential impact of HPV prophylactic vaccines.

    Authors: Cathy Ndiaye, Laia Alemany, Yankhoba Diop, Nafissatou Ndiaye, Marie-Joseph Diémé, Sara Tous, Jo Ellen Klaustermeier, Maria Alejo, Xavier Castellsagué, F Xavier Bosch, Helen Trottier and Silvia de Sanjosé
    Citation: Infectious Agents and Cancer 2013 8:14
    Content type: Short report Published on:

  28. c-Met is a receptor tyrosine kinase that encodes protein such as hepatocyte growth factor receptor (HGFR). Inappropriate activity of c-Met can cause wide variety of carcinomas. c-Met inhibitor are relatively n...

    Authors: Anum Mughal, Hafiz Muhammad Aslam, Asfandyar Sheikh, Agha Muhammad Hammad Khan and Shafaq Saleem
    Citation: Infectious Agents and Cancer 2013 8:13
    Content type: Letter to the Editor Published on:

  29. It has been hypothesized that human cytomegalovirus (HCMV) may be associated with breast cancer progression. However, the role of HCMV infection in breast cancer remains controversial. We aimed to assess wheth...

    Authors: Dolores Utrera-Barillas, Hilda-Alicia Valdez-Salazar, David Gómez-Rangel, Isabel Alvarado-Cabrero, Penélope Aguilera, Alejandro Gómez-Delgado and Martha-Eugenia Ruiz-Tachiquin
    Citation: Infectious Agents and Cancer 2013 8:12
    Content type: Short report Published on:

  32. The purpose of this study was to determine if any relationship exists between expression of COX2 and iNOS markers and urinary schistosomiasis in bladder cancers.

    Authors: Hassan Elsiddig Hassan, Ahmed Abdel Badie Mohamed, Amel Omer Bakhiet and Hussain Gadelkarim Ahmed
    Citation: Infectious Agents and Cancer 2013 8:9
    Content type: Research article Published on:

  33. The obligate intracellular protozoan parasite Toxoplasma gondii infects humans and other warm-blooded animals and establishes a chronic infection in the central nervous system after invasion. Studies showing a po...

    Authors: Sivasakthivel Thirugnanam, Namita Rout and Munirathinam Gnanasekar
    Citation: Infectious Agents and Cancer 2013 8:8
    Content type: Hypothesis Published on:

  35. The rationale behind current worldwide human papilloma virus (HPV) vaccination programs starts from two basic premises, 1) that HPV vaccines will prevent cervical cancers and save lives and, 2) have no risk of...

    Authors: Lucija Tomljenovic, Judy Wilyman, Eva Vanamee, Toni Bark and Christopher A Shaw
    Citation: Infectious Agents and Cancer 2013 8:6
    Content type: Letter to the Editor Published on:

  36. Only a small portion of HPV 16 infections persist and can lead to cervical intraepithelial lesions and cancer. Factors that favour HPV persistence versus clearance are still poorly understood, but several stud...

    Authors: Iris Cornet, Tarik Gheit, Gary M Clifford, Jean-Damien Combes, Véronique Dalstein, Silvia Franceschi, Massimo Tommasino and Christine Clavel
    Citation: Infectious Agents and Cancer 2013 8:4
    Content type: Research article Published on:

  37. Kaposi sarcoma-associated herpesvirus (KSHV) seropositivity is associated with sexual, environmental, and socioeconomic exposures. Whether these characteristics are independent risk factors is uncertain becaus...

    Authors: Joanne T Chang, Fatma M Shebl, Ruth M Pfeiffer, Benon Biryahwaho, Barry I Graubard and Sam M Mbulaiteye
    Citation: Infectious Agents and Cancer 2013 8:3
    Content type: Research article Published on:

  38. Human papillomavirus (HPV) infection accounts for about 40-50% of all cases of penile carcinoma suggesting that other factors, including host genetic status, are involved in neoplastic transformation. In this ...

    Authors: Clorinda Annunziata, Luigi Buonaguro, Simona Losito, Franco M Buonaguro and Maria Lina Tornesello
    Citation: Infectious Agents and Cancer 2013 8:2
    Content type: Research article Published on:

  39. Bovine papillomaviruses (BPVs) are oncogenic DNA viruses, which mainly induce benign lesions of cutaneous and/or mucosal epithelia in cattle. Thirteen (BPV 1–13) different viral genotypes have been characteriz...

    Authors: Annunziata Corteggio, Gennaro Altamura, Franco Roperto and Giuseppe Borzacchiello
    Citation: Infectious Agents and Cancer 2013 8:1
    Content type: Review Published on:

  40. Information on human papillomavirus (HPV) type distribution is necessary to evaluate the potential impact of current and future HPV vaccines. We estimated the relative contribution (RC) to invasive cervical ca...

    Authors: Beatriz Serrano, Laia Alemany, Sara Tous, Laia Bruni, Gary M Clifford, Thomas Weiss, Francesc Xavier Bosch and Silvia de Sanjosé
    Citation: Infectious Agents and Cancer 2012 7:38
    Content type: Research article Published on:

  41. Human Papilloma Virus (HPV) is a major leading cause of Human Cancer. Through the HPV Prevention series we would like to highlight the quality and the breadth of the research being carried out on the Control a...

    Authors: Silvia de Sanjosé
    Citation: Infectious Agents and Cancer 2012 7:37
    Content type: Editorial Published on:

  42. Nasopharyngeal carcinomas (NPC) are consistently associated with the Epstein-Barr virus (EBV). Though NPCs are more radiosensitive and chemosensitive than other tumors of the upper aero-digestive tract, many t...

    Authors: Benjamin Vérillaud, Mélanie Gressette, Yannis Morel, Carine Paturel, Philippe Herman, Kwok Wai Lo, Sai Wah Tsao, Michel Wassef, Anne-Sophie Jimenez-Pailhes and Pierre Busson
    Citation: Infectious Agents and Cancer 2012 7:36
    Content type: Research article Published on:

  43. Since the late 1990s, infectious agents have been thought to play a role in the pathogenesis of approximately 15% of cancers. It is now widely accepted that infection of stomach tissue with the bacteria Helicobac...

    Authors: Kenneth Alibek, Nargis Karatayeva and Ildar Bekniyazov
    Citation: Infectious Agents and Cancer 2012 7:35
    Content type: Review Published on:

  44. Human Papillomavirus (HPV) in cervical epithelium has been identified as the main etiological factor in the developing of Cervical Cancer (CC), which has recently become a public health problem in Mexico. This...

    Authors: Raúl Peralta-Rodríguez, Pablo Romero-Morelos, Vanessa Villegas-Ruíz, Mónica Mendoza-Rodríguez, Keiko Taniguchi-Ponciano, Beatriz González-Yebra, Daniel Marrero-Rodríguez and Mauricio Salcedo
    Citation: Infectious Agents and Cancer 2012 7:34
    Content type: Research article Published on:

  45. Recent clinical and pre-clinical data demonstrate that adjuvant antimicrobial therapy is beneficial in cancer treatment. There could be several reasons for this effect, which include treating cancer associated...

    Authors: Kenneth Alibek, Aliya Bekmurzayeva, Assel Mussabekova and Bolat Sultankulov
    Citation: Infectious Agents and Cancer 2012 7:33
    Content type: Review Published on:

  46. Women with Human Papilloma Virus (HPV) persistence are characterized by high levels of IL-10 at cervix. We have determined whether polymorphisms of IL-10 gene promoter might be associated with increased risk o...

    Authors: Kirvis Torres-Poveda, Ana I Burguete-García, Miguel Cruz, Gabriela A Martínez-Nava, Margarita Bahena-Román, Esmeralda Ortíz-Flores, Abrahan Ramírez-González, Guillermina López-Estrada, Karina Delgado-Romero and Vicente Madrid-Marina
    Citation: Infectious Agents and Cancer 2012 7:32
    Content type: Research article Published on:

  47. Infectious etiology in lymphoproliferative diseases has always been suspected. The pathogenic roles of human herpesvirus-6 (HHV-6) in acute leukemia have been of great interest. Discordant results to establish...

    Authors: Nefzi Faten, Gautheret-Dejean Agnès, Ben Fredj Nadia, Abid Ben Salem Nabil, Zaier Monia, Khelif Abderrahim, Agut Henri, Feki Salma and Aouni Mahjoub
    Citation: Infectious Agents and Cancer 2012 7:31
    Content type: Research article Published on:

  48. The major cause of cervical intraepithelial neoplasia (CIN) is persistent infection with human papillomavirus (HPV). Most CIN grade 2 and 3 lesions are treated with cone excision, although a substantial propor...

    Authors: Ane Cecilie Munk, Irene Tveiterås Øvestad, Einar Gudlaugsson, Kjell Løvslett, Bent Fiane, Bianca van Diermen-Hidle, Arnold-Jan Kruse, Ivar Skaland, Emiel AM Janssen and Jan PA Baak
    Citation: Infectious Agents and Cancer 2012 7:30
    Content type: Research article Published on:

  49. The Hedgehog (Hh) proteins comprise a group of secreted proteins that regulate cell growth, differentiation and survival. Inappropriate activation of the Hh signaling pathway has been implicated in the develop...

    Authors: Asfandyar Sheikh, Arsalan Ahmad Alvi, Hafiz Muhammad Aslam and Abdul Haseeb
    Citation: Infectious Agents and Cancer 2012 7:29
    Content type: Letter to the Editor Published on:

  50. The epidemic of HIV in sub-Saharan Africa varies significantly across countries in the region with high prevalence in Southern Africa and Nigeria. Cancer is increasingly identified as a complication of HIV inf...

    Authors: Elima Jedy-Agba and Clement Adebamowo
    Citation: Infectious Agents and Cancer 2012 7:28
    Content type: Research article Published on:

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