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Table 2 Plating and Replating of lung and spleen for P-MAPA, MXF and MXF + P-MAPA antimycobacterial activities

From: Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer

Compounds

Tissues

 

Lung

Spleen

Spleen Replate

 

Mean CFU

log10 prot

SEM

n

Mean CFU

log10 prot

SEM

n

Mean CFU

log10prot

SEM

n

Untreated Ctrl

4.66

-

0.11

6/6

4.29

-

0.12

6/6

3.34

-

0.18

6/6

MXF

2.86a

1.80

0.13

6/6

2.80a

1.49

0.23

6/6

1.38a

1.96

0.29

5/6

P-MAPA

3.72a

0.94

0.10

6/6

3.74

0.55

0.12

6/6

2.31a

1.03

0.12

6/6

MXF + P-MAPA

2.91a

1.75

0.14

6/6

2.36a

1.93

0.32

6/6

0.69a

2.65

0.32

4/6

  1. n = Number of mice with CFU/total number of mice at sacrifice; MXF = Moxifloxacin; SEM = standard error of the mean; log10 prot = log10 CFU of protection; Letter a: significantly different from Untreated Ctrl group.