Histopathological analysis in urinary tract of the animals from CT (a), MNU (b, c), BCG (d) and P-MAPA (e) groups. In (a) and (e) the urinary tract showed normal features. (b) Lesion widespread in different points of the urinary tract: hydronephrosis the and papillary lesions (arrows) in the kidneys; hydroureter (open arrowheads); thickening of the wall the of the urinary bladder and pappillary lesions (solid arrowhead). (c) Intravesical pappillary lesions (arrow); hydroureter. (d) Cystic lesions (arrow) in the kidney; hydroureter (open arrowhead); thickening of the wall of the urinary bladder and papillary lesions (solid arrowhead). a - e: LK - left kidney, LU - left ureter, RK - right kidney, RU - right ureter, UB - urinary bladder. Figure 2f: The animals from the MNU and BCG group showed macroscopic haematuria (arrow). P-MAPA group showed no macroscopic haematuria.