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Figure 1 | Infectious Agents and Cancer

Figure 1

From: Bacteria under SOS evolve anticancer phenotypes

Figure 1

The SOS response. LexA and RecA control the SOS genes that encode functions required for DNA damage repair. LexA represses these genes. DNA damage activates RecA to stimulate autocatalytic cleavage of LexA so that the SOS genes are derepressed and expressed for repair. Cell division is inhibited and delayed resulting filamentation to allow repair before cell division.

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Infectious Agents and Cancer

ISSN: 1750-9378

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