Table 1 Immunization schedule of the study

PR_{75–84 wt}

IFA

VLVGPTPVNI

4 × 50 μg

s.c

Downward pointing triangle

PR_{75–84 d.mut}

IFA

VLVGPTPF NV

4 × 50 μg

s.c

Black filled Diamond

PR_{75–84 d.mut} low²

-

VLVGPTPF NV

4 × 5 μg

s.c

Blue open Diamond

RBC-PR_{75–84 wt}

RBC

VLVGPTPVNI biotinylated to synergeneic erythrocytes

2 × 5 ng³ + 2 × 12.5 ng⁴

i.p

Square

RBC-PR_{75–84 d.mut}

RBC

VLVGPTPF NV biotinylated to syngeneic erythrocytes

2 × 5 ng³ + 2 × 12.5 ng⁴

i.p

Triangle

RBC_empty

RBC

Biotinylated syngeneic erythrocytes

3 × 200 μl + 1 × 500 μl blood

i.p

Circle

Untreated

-

-

-

-

Cross