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Table 2 Predictors of HCC by univariate and multivariate logistic regression analysis

From: Development and validation of a nomogram for assessing hepatocellular carcinoma risk after SVR in hepatitis C patients with advanced fibrosis and cirrhosis

Baseline variables

Univariate analysis

Multivariate analysis

Hazard ratio

95%CI

p Value

Hazard ratio

95%CI

p Value

Age, years

1.08

(1.02–1.14)

0.006

1.08

(1.02–1.14)

0.009

Male

2.46

(1.25–4.83)

0.009

2.38

(1.10–5.13)

0.027

BMI (kg/m2)

0.93

(0.85–1.02)

0.143

   

Hypertension

0.56

(0.27–1.19)

0.132

   

Diabetes

1.19

(0.57–2.45)

0.650

   

Alcohol use disorder

2.65

(1.28–5.47)

0.009

   

Antiviral regimen

PEG ± RBV

 

Reference

    

DAA

2.77

(1.24–6.20)

0.013

   

PR + DAA

1.67

(0.58–4.81)

0.343

   

Platelets (× 109/L)

0.99

(0.99–1.00)

0.004

   

ALT (IU/L)

1.00

(1.00–1.01)

0.662

   

Albumin (g/L)

0.89

(0.84–0.93)

 < 0.001

0.92

(0.86–1.00)

0.037

Bilirubin (µmol/L)

1.03

(1.02–1.05)

 < 0.001

   

INR

18.82

(4.78–74.29)

 < 0.001

   

Alpha-fetoprotein (ng/mL)

1.01

(0.99–1.02)

0.408

   

LSM (kPa)

1.05

(1.03–1.07)

 < 0.001

1.03

(1.01–1.06)

0.001

Delta-LSM (kPa)

1.04

(1.01–1.08)

0.022

   

FIB-4 score

1.10

(1.06–1.15)

 < 0.001

   

Delta-FIB-4 score

1.14

(1.07–1.21)

 < 0.001

   
  1. The bold values were considered statistical significance
  2. CI confidence interval, HR hazards ratios
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Infectious Agents and Cancer

ISSN: 1750-9378

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