Fig. 4

Constructing the LASSO–Cox model. A Forrest plot of prognostic genes. B, C LASSO-penalized Cox analysis conducted to build a prognostic model. D Kaplan–Meier survival analysis for six-gene signature, including FAM98A, NOP56, BMI1, GHR, TMEM106C, and UBE2E1. E, F Overall survival of patients in TCGA cohort. G, H Univariate and multivariate regression analyses showing the association between risk score and clinicopathological characteristics in relation to overall survival in TCGA cohort. Green represents univariate analysis results; red represents multivariate analysis results