Table 2 Mutations detected in LT-Antigen coding sequences
Sample | Synonymous mutations | Domain | Nonsynonymous mutations | Domain | Stop mutations | Domain |
|---|---|---|---|---|---|---|
SS1 | ||||||
SS2 | 2393 T→ C (Ile) | helicase | 1102 G→A (Arg→Lys) | Rb | ||
MCC1 | 2210 G→A(Arg) | helicase | 253 G→T (Ala→Ser) | exon 1 | ||
MCC2 | 253 G→T (Ala→Ser) 1666 A→G (Glu→Gly) 1766 G→C (Arg→Thr) 1768 T→C (Val→Ala) 1998 T→A (Phe→Ile) 2467 C→G (Ala→Gly) | exon 1 OBD OBD OBD helicase helicase | 1504 C→G (Ser→Stop) | Rb-OBD | ||
Poro1 | 2393 T→C (Ile) | helicase | ||||
Poro2 | 1265 C→T (Phe) 2327 G→A (Glu) | Rb helicase | 2453 G→T (Leu→Phe) | helicase |