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Table 2 Age-standardised mortality rate among U.S. women with gynaecologic cancer by age group, 2010–2022

From: Trends in gynaecologic cancer mortality and the impact of the COVID-19 pandemic in the United States

Age-standardized Mortality Rate (Per 100,000 Persons)

 

Age Years

Pre-Pandemic Referent Epoch 2010

Pre-Pandemic Referent Epoch 2019

Pandemic Epoch 1 2020

 

Pandemic Epoch 2 2021

 

Pandemic Epoch 3 2022

Observed

Predicted [95% CI]

%Increase*

 

Observed

Predicted [95% CI]

%Increase*

 

Observed

Predicted [95% CI]

%Increase*

Gynecologic Cancer†

Overall

11.109

10.160

10.491

10.011 [9.275–10.746]

+ 4.796

 

10.677

9.677 [8.300-11.054]

+ 10.333

 

10.596

9.185 [6.891–11.478]

+ 15.366

Age

    

25–44 years

1.673

1.627

1.682

1.613 [1.549–1.676]

+ 4.254

 

1.882

1.605 [1.532–1.678]

+ 17.234

 

1.63

1.598 [1.515–1.681]

+ 1.819

45–64 years

9.425

8.807

9.125

8.769 [7.775–9.763]

+ 4.060

 

8.968

8.476 [6.613–10.338]

+ 5.804

 

8.889

8.050 [4.949–11.151]

+ 10.427

≥ 65 years

36.331

32.668

33.677

32.102 [30.010-34.195]

+ 4.905

 

34.432

30.998 [27.077–34.919]

+ 11.077

 

34.758

29.338 [22.809–35.867]

+ 18.474

Ovarian Cancer

Overall

7.189

5.517

5.497

5.381 [5.257–5.505]

+ 2.157

 

5.514

5.206 [5.064–5.348]

+ 5.924

 

5.483

5.031 [4.871–5.191]

+ 8.990

Age

    

25–44 years

0.582

0.527

0.473

0.493 [0.410–0.576]

-4.124

 

0.473

0.481 [0.363–0.598]

-1.732

 

0.518

0.468 [0.308–0.627]

+ 10.713

45–64 years

5.621

4.529

4.629

4.443 [3.889–4.997]

+ 4.178

 

4.411

4.233 [3.194–5.271]

+ 4.199

 

4.411

3.973 [2.243–5.702]

+ 11.018

≥ 65 years

25.533

19.028

18.878

17.926 [16.801–19.052]

+ 5.309

 

19.350

16.632 [14.524–18.741]

+ 16.336

 

19.083

15.071 [11.560-18.582]

+ 26.618

Cervical Cancer

Overall

2.038

1.937

2.034

1.939 [1.892–1.985]

+ 4.921

 

2.112

1.925 [1.871–1.978]

+ 9.730

 

1.950

1.911 [1.851–1.971]

+ 2.025

Age

    

25–44 years

0.936

0.945

1.045

0.906 [0.865–0.948]

+ 15.38

 

1.145

0.872 [0.813–0.931]

+ 31.346

 

0.900

0.833 [0.753–0.912]

+ 8.028

45–64 years

2.457

2.396

2.457

2.385 [2.284–2.486]

+ 3.034

 

2.457

2.376 [2.260–2.491]

+ 3.428

 

2.357

2.367 [2.236–2.497]

-0.416

≥ 65 years

3.898

3.471

3.624

3.452 [3.242–3.662]

+ 4.996

 

3.786

3.400 [3.160–3.640]

+ 11.356

 

3.711

3.348 [3.077–3.620]

+ 10.832

Uterine Corpus Cancer

Overall

1.905

2.787

3.033

2.925 [2.548–3.303]

+ 3.678

 

3.079

2.981 [2.274-3. 689]

+ 3.302

 

3.211

2.962 [1.784–4.139]

+ 8.421

Age

    

25–44 years

0.109

0.209

0.209

0.169 [0.109–0.229]

+ 23.640

 

0.264

0.176 [0.108–0.245]

+ 49.519

 

0.209

0.184 [0.106–0.261]

+ 13.624

45–64 years

1.386

1.982

2.139

2.037 [1.619–2.454]

+ 5.048

 

2.100

1.973 [1.190–2.756]

+ 6.449

 

2.161

1.824 [0.520–3.128]

+ 18.461

≥ 65 years

7.052

10.282

11.264

10.888 [9.704–12.072]

+ 3.453

 

11.444

11.190 [8.972–13.409]

+ 2.271

 

12.141

11.230 [7.534–14.922]

+ 8.116

  1. Age data is presented in years. NA, not applicable. †Gynaecologic cancer includes cervix uteri (International Statistical Classification of Disease and Related Health Problems, 10th revision [ICD-10] code C53), corpus uteri (ICD-10 code C54), and ovary (ICD-10 code C56). *Denotes the % increase from predicted to observed value
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Infectious Agents and Cancer

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