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Table 1 Results from triaging with cytology, genotyping and methylation

From: Molecular triage of cervical screening samples in women 55–59 years of age: a pilot study

Triage test

hrHPV pos, n

Triage test pos, n

Normal histo, n

LSIL

histo, n

NPV

≥LSIL

PPV

≥LSIL

FNR

≥LSIL

HSIL

histo, n

NPV

≥HSIL

PPV

≥HSIL

FNR

≥HSIL

Cytology

49

12

7

0

0.73

0.42

67

5

0.95

0.42

29

Genotyping

49

30

20

4

0.74

0.33

33

6

0.95

0.2

14

Methylation

48

35

24

6

0.69

0.31

27

5

0.85

0.14

29

  1. Abbreviations: hrHPV, high-risk HPV; histo, histology; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; NPV, negative predictive value; PPV, positive predictive value; FNR, false negative rate.
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Infectious Agents and Cancer

ISSN: 1750-9378

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