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Fig. 6 | Infectious Agents and Cancer

Fig. 6

From: Pyroptosis patterns influence the clinical outcome and immune microenvironment characterization in HPV-positive head and neck squamous cell carcinoma

Fig. 6

Construction and validation of Pyroscore. (A) Alluvial diagram showing the distributions of pyroclusters, geneclusters, Pyroscores and survival outcomes. (B) Pyroscore is differentially expressed in pyrocluster A and B. (C) Pyroscore is differentially expressed in genecluster A and B. (D) Kaplan-Meier survival analysis shows a significant difference in overall survival time between high and low Pyroscore groups in training sets (TCGA-HNSCC and GSE65858 cohorts). (E) Kaplan-Meier analysis of overall survival time between high and low Pyroscore groups in internal testing set (TCGA-HNSCC cohort). (F) Kaplan-Meier analysis of overall survival time between high and low Pyroscore groups in internal testing set (GSE65858 cohort). (G) The correlations among Pyroscore and PRGs. Red dots denote positive correlations and blue dots denote negative correlations. Larger and deeper dots represent stronger correlations

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Infectious Agents and Cancer

ISSN: 1750-9378

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