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Fig. 2 | Infectious Agents and Cancer

Fig. 2

From: Pyroptosis patterns influence the clinical outcome and immune microenvironment characterization in HPV-positive head and neck squamous cell carcinoma

Fig. 2

Unsupervised learning to identify two pyroclusters based on the expression of 27 PRGs. (A) Consensus clustering matrix defining two patterns (k = 2) in TCGA-HNSCC and GSE65858 cohorts. (B) The cumulative distribution function of clustering. (C) The two pyroclusters have a substantial difference in overall survival time according to Kaplan-Meier survival analysis. (D) The heatmap shows the clinicopathological traits and unsupervised clustering of the 27 PRGs in TCGA-HNSCC and GSE65858 cohorts. Red denotes higher expression, whereas blue denotes lower expression. (E) Relative expression levels of 27 PRGs between the two pyroclusters

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