Table 4 Correlation between HBV serological markers in NA-treated patients according to HBeAg Status
From: Levels of HBV RNA in chronic HBV infected patients during first-line nucleos(t)ide analogues therapy
HBeAg-positive | HBeAg-negative | |||
|---|---|---|---|---|
HBV DNA | HBsAg | HBV DNA | HBsAg | |
Week 12 of NA therapy | ||||
HBV RNA | 0.594(P < 0.05*) | 0.540(P < 0.05*) | 0.444(P < 0.05*) | 0.358(P = 0.094) |
HBV DNA | – | 0.534(P < 0.05*) | – | 0.551(P < 0.05*) |
Week 24 of NA therapy | ||||
HBV RNA | 0.792(P < 0.05*) | 0.377(P < 0.05*) | − 0.208(P = 0.517) | 0.131(P = 0.685) |
HBV DNA | –- | 0.381(P < 0.05*) | –- | 0.021(P = 0.949) |
Week 48 of NA therapy | ||||
HBV RNA | 0.770(P < 0.05*) | 0.201(P = 0.383) | 0.230(P = 0.551) | 0.297 (P = 0.438) |
HBV DNA | – | 0.011(P = 0.963) | – | 0.365(P = 0.334) |