From: Hepatitis B or C viral infection and the risk of cervical cancer
Variable | Cases | Controls | Univariable | Multivariable | ||||||
---|---|---|---|---|---|---|---|---|---|---|
(n = 838) | (n = 838) | |||||||||
No | % | No | % | OR | 95%CI | P | AOR | 95%CI | P | |
HPV | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 HPV-negative | 141 | 15.5 | 768 | 91.6 |  | 1(reference) |  |  | 1(reference) |  |
 HPV-positive | 697 | 84.5 | 70 | 8.4 | 55.2 | 40.6–75.1 |  < 0.001 | 57.5 | 41.8–79.2 |  < 0.001 |
Family history of cancer | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 No | 828 | 98.8 | 819 | 97.7 |  | 1(reference) |  |  |  |  |
 Yes | 10 | 1.2 | 19 | 2.3 | 0.5 | 0.2–1.1 | 0.106 |  |  |  |
Cigarette smoking | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 No | 834 | 99.5 | 837 | 99.9 |  | 1(reference) |  |  |  |  |
 Yes | 4 | 0.5 | 1 | 0.1 | 4 | 0.4–36.6 | 0.214 |  |  |  |
Alcohol drinking | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 No | 836 | 99.8 | 838 | 100 |  | 1(reference) |  |  |  |  |
 Yes | 2 | 0.2 | 0 | 0 | – | – | – |  |  |  |
BMI | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
  < 18.5 | 78 | 9.3 | 67 | 8 |  | 1(reference) |  |  |  |  |
 18.5–25 | 587 | 70 | 573 | 68.4 | 0.9 | 0.6–1.2 | 0.438 |  |  |  |
 25–30 | 150 | 17.9 | 163 | 19.5 | 0.8 | 0.5–1.2 | 0.215 |  |  |  |
  > 30 | 23 | 2.7 | 35 | 4.2 | 0.6 | 0.3–1.0 | 0.061 |  |  |  |
No.full-term pregnancies | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 0 | 40 | 4.8 | 93 | 11.1 |  | 1(reference) |  |  | 1(reference) |  |
 1 | 243 | 29 | 366 | 43.7 | 1.9 | 1.2–2.8 | 0.004 | 1.7 | 0.9–3.2 | 0.091 |
 2 | 343 | 40.9 | 263 | 31.4 | 3.9 | 2.5–6.0 |  < 0.001 | 4.1 | 2.2–7.8 |  < 0.001 |
 3 | 116 | 13.8 | 63 | 7.5 | 5.7 | 3.4–9.6 |  < 0.001 | 7 | 3.3–14.7 |  < 0.001 |
  > 3 | 96 | 11.5 | 53 | 6.3 | 6.4 | 3.7–11.1 |  < 0.001 | 4.1 | 1.8–9.3 | 0.001 |
HCV markers | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Anti-HCV-negative | 828 | 98.8 | 838 | 100 |  | 1(reference) |  |  |  |  |
 Anti-HCV-positive | 10 | 1.2 | 0 | 0 | – | – | – |  |  |  |
HBV infection status | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 HBsAg-negative/anti-HBc-negativea | 686 | 81.9 | 740 | 88.3 |  | 1(reference) |  |  | 1(reference) |  |
 HBsAg-positive/anti-HBc-positiveb | 53 | 6.3 | 37 | 4.4 | 1.6 | 1.0–2.4 | 0.041 | 1.3 | 0.7–2.6 | 0.402 |
 HBsAg-negative/anti-HBc-positivec | 97 | 11.6 | 61 | 7.3 | 1.7 | 1.2–2.4 | 0.001 | 1.6 | 0.9–2.6 | 0.083 |