Table 3 A univariate analysis of factors related to OS in HCC patients treated with TACE
ΔLDH ≥ 80 vs ΔLDH within ± 80 | ΔLDH ≤ − 80 vsΔLDH within ± 80 | |||
|---|---|---|---|---|
Statistics | HR (95% CI) | Statistics | HR (95% CI) | |
Gender | ||||
Male | 491 (92.29%) | 1 | 602 (91.07%) | 1 |
Female | 41 (7.71%) | 1.08 (0.70, 1.68) | 59 (8.93%) | 1.22 (0.85, 1.75) |
Age (years) | ||||
< 55 | 272 (51.13%) | 1 | 335 (50.68%) | 1 |
≥ 55 | 260 (48.87%) | 0.87 (0.69, 1.09) | 326 (49.32%) | 0.85 (0.69, 1.06) |
PS score | ||||
0 | 448 (84.21%) | 1 | 561 (84.87%) | 1 |
1 | 84 (15.79%) | 3.07 (2.29, 4.11) | 100 (15.13%) | 3.35 (2.56, 4.38) |
Diameter of main tumour (cm) | ||||
< 5 | 215 (40.41%) | 1 | 278 (42.06%) | 1 |
≥ 5 | 317 (59.59%) | 3.32 (2.60, 4.23) | 383 (57.94%) | 3.05 (2.44, 3.81) |
AFP (ng/mL) | ||||
< 25 | 232 (43.61%) | 1 | 306 (46.29%) | 1 |
≥ 25 | 300 (56.39%) | 2.27 (1.77, 2.90) | 355 (53.71%) | 2.53 (2.03, 3.16) |
Hgb (g/L) | ||||
< 120 | 136 (25.56%) | 1 | 161 (24.36%) | 1 |
≥ 120 | 396 (74.44%) | 0.72 (0.56, 0.93) | 500 (75.64%) | 0.69 (0.54, 0.87) |
WBC (109/L) | ||||
< 11 | 495 (93.05%) | 1 | 620 (93.8%) | 1 |
≥ 11 | 37 (6.95%) | 1.80 (1.20, 2.70) | 41 (6.20%) | 1.43 (0.95, 2.14) |
No. of intrahepatic | ||||
lesions | ||||
0 | 214 (40.23%) | 1 | 277 (41.91%) | 1 |
≤ 3 | 126 (23.68%) | 2.10 (1.53, 2.90) | 154 (23.30%) | 2.35 (1.77, 3.13) |
> 3 | 192 (36.09%) | 4.07 (3.05, 5.44) | 232 (34.80%) | 4.08 (3.14, 5.29) |
Location of Lesions | ||||
None | 214 (40.23%) | 1 | 277 (41.91%) | 1 |
Left/right | 135 (25.38%) | 2.12 (1.54, 2.91) | 160 (24.21%) | 2.33 (1.75, 3.10) |
Both | 183 (34.40%) | 4.11 (3.08, 5.48) | 224 (33.89%) | 4.15 (3.19, 5.38) |
Child–Pugh class | ||||
A | 392 (73.68%) | 1 | 522 (78.97%) | 1 |
B | 140 (26.32%) | 1.84 (1.43, 2.36) | 139 (21.03%) | 2.11 (1.65, 2.68) |