Table 5 Subgroup analysis of the association between GLR and the risk of recurrence of HCC with staging I–II
Parameters | N | HR | 95%CI Low | 95%CI High | P value | P (interaction) | |
|---|---|---|---|---|---|---|---|
Age (years) | 0.4760 | ||||||
≤ 60 | 329 | 1.002 | 1.000 | 1.004 | 0.0313 | ||
> 60 | 133 | 1.003 | 1.000 | 1.007 | 0.0664 | ||
Sex | 0.6469 | ||||||
Male | 367 | 1.002 | 1.000 | 1.004 | 0.0169 | ||
Female | 95 | 1.003 | 0.998 | 1.008 | 0.2005 | ||
Smoking | 0.2988 | ||||||
No | 298 | 1.001 | 0.999 | 1.004 | 0.3412 | ||
Yes | 164 | 1.003 | 1.001 | 1.005 | 0.0047 | ||
Allogeneic blood | 0.1524 | ||||||
No | 396 | 1.002 | 1.000 | 1.003 | 0.0514 | ||
Yes | 66 | 1.005 | 1.001 | 1.010 | 0.0209 | ||
HBsAg | 0.0341 | ||||||
Negative | 69 | 1.007 | 1.003 | 1.012 | 0.0023 | ||
Positive | 393 | 1.002 | 1.000 | 1.003 | 0.0589 | ||
AFP (ng/ml) | |||||||
≤ 20 | 208 | 1.005 | 1.002 | 1.009 | 0.0014 | 0.0416 | |
> 20 | 254 | 1.002 | 1.000 | 1.003 | 0.1016 | ||
Lymphovascular invasion | 0.0980 | ||||||
No | 362 | 1.001 | 0.999 | 1.003 | 0.2805 | ||
Yes | 100 | 1.004 | 1.001 | 1.006 | 0.0011 | ||
Tumor number | 0.0654 | ||||||
Single | 431 | 1.002 | 1.000 | 1.003 | 0.0662 | ||
Multiple | 31 | 1.006 | 1.002 | 1.009 | 0.0011 | ||
Tumor size (cm) | 0.2891 | ||||||
≤ 5 | 309 | 1.003 | 1.001 | 1.005 | 0.0057 | ||
> 5 | 153 | 1.001 | 0.999 | 1.004 | 0.2617 | ||