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Table 2 The average tumor weight of the HPV16, 18 and 58 groups of tumor-bearing mice after immunization with different immune substances (g)

From: Construction and immune effect of an HPV16/18/58 trivalent therapeutic adenovirus vector vaccine

Group

TC-1 group

U14/LV-HPV18 E6E7 group

U14/LV-HPV58 E6E7 group

AD-HPV16/18/58 mE6E7 vaccine group

0.322 ± 0.18*

0.344 ± 0.17

2.103 ± 1.220*

AD-NC group

0.902 ± 0.39

0.985 ± 0.57

5.862 ± 0.323

PBS group

0.926 ± 0.50

0.940 ± 0.52

5.959 ± 1.059

  1. Control groups are the AD-NC group and PBS group
  2. *Compared with that of the control group, the average tumor weight of the mice in the vaccine group was significantly reduced (P < 0.05)