Fig. 3
From: Silencing of UBE2D1 inhibited cell migration in gastric cancer, decreasing ubiquitination of SMAD4
Silencing of UBE2D1 suppressed cell migration. A, B Transwell (A) and wound healing B assays were performed to analyze cell migration after transduction with shUBE2D1 lentiviruses in AGS and MKN45 cells. ***, P < 0.001 versus shNC. C A western blot assay was performed to measure the protein levels of UBE2D1, MMP2, and MMP9. D The lung metastatic nodules were much less in the shUBE2D1 mice than those in the shNC mice. ***, P < 0.001 versus shNC. Scale: 100 µm