Table 1 Demographic and clinical characteristics of patients with oropharyngeal squamous cell carcinoma presenting to the American University of Beirut Medical Center from 1972 to 2017
From: HPV-related oropharyngeal cancer prevalence in a middle eastern population using E6/E7 PCR
Descriptive | Overall N = 34 | HPV Negative N = 5 | HPV Positive N = 29 | P-value |
|---|---|---|---|---|
Age at diagnosis in years, mean(sd) | 58.9 (9.3) | 57.6 (7.8) | 59.1 (9.6) | 0.645 |
Male, n(%) | 25 (73.5) | 3 (60.0) | 22 (75.9) | 0.591 |
Country, n(%)ss | 1.000 | |||
Lebanon | 27 (79.4) | 5 (100) | 22 (75.9) | |
Syria | 3 (8.8) | 0 (0) | 3 (10.3) | |
Palestinian Territories | 1 (2.9) | 0 (0) | 1 (3.4) | |
Jordan | 1 (2.9) | 0 (0) | 1 (3.4) | |
Iraq | 2 (5.9) | 0 (0) | 2 (6.9) | |
Tobacco use, n(%) | 24 (75.0) | 3 (75.0) | 21 (75.0) | 1.000 |
Any alcohol use, n(%) | 16 (50.0) | 2 (50.0) | 14 (50.0) | 1.000 |
Social | 7 (46.7) | 1 (50.0) | 6 (46.2) | |
Daily | 8 (53.3) | 1 (50.0) | 7 (53.8) | |
Primary site, n(%) | 1.000 | |||
Tonsil | 14 (41.2) | 2 (40.0) | 12 (41.4) | |
BOT | 17 (50.0) | 3 (60.0) | 14 (48.3) | |
Soft Palate | 3 (8.8) | 0 (0) | 3 (10.3) | |
Stage at presentation, n(%) | 0.660 | |||
I | 1 (3.0) | 0 (0) | 1 (3.6) | |
II | 1 (3.0) | 0 (0) | 1 (3.6) | |
III | 4 (12.1) | 1 (20.0) | 3 (10.7) | |
IV | 27 (81.8) | 4 (80.0) | 23 (82.1) | |
Clinical T stage, n(%) | 1.000 | |||
TX | 3 (10.0) | 0 (0) | 3 (11.5) | |
T1 | 3 (10.0) | 0 (0) | 3 (11.5) | |
T2 | 9 (30.0) | 1 (25.0) | 8 (30.8) | |
T3 | 6 (20.0) | 1 (25.0) | 5 (19.2) | |
T4 | 9 (30.0) | 2 (50.0) | 7 (26.9) | |
Clinical N stage, n(%) | 0.121 | |||
NX | 1 (3.2) | 1 (25.0) | 0 (0) | |
N0 | 4 (12.9) | 0 (0) | 4 (14.8) | |
N1 | 4 (12.9) | 1 (25.0) | 3 (11.1) | |
N2 | 22 (71.0) | 2 (50.0) | 20 (74.1) | |
N3 | 0 (0) | 0 (0) | 0 (0) | |
M stage, n(%) | 0.359 | |||
MX | 1 (3.1) | 0 (0) | 1 (3.7) | |
M0 | 25 (78.1) | 3 (60.0) | 22 (81.5) | |
M1 | 6 (18.8) | 2 (40.0) | 4 (14.8) | |
Surgery only, n(%) | 5 (14.7) | 0 (0) | 5 (17.2) | |
Surgery + Radiation, n(%) | 1 (2.9) | 1 (20) | 0 (0) | |
Surgery + Radiation + Systemic therapy, n(%) | 7 (20.6) | 1 (20) | 6 (20.7) | |
Radiation only, n(%) | 2 (5.9) | 0 (0) | 2 (6.9) | |
Radiation + Systemic therapy, n(%) | 14 (41.2) | 2 (40) | 12 (41.4) | |
Systemic therapy only, n(%) | 1 (2.9) | 1 (20) | 0 (0) | |