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Table 5 The time and average of patients’ overall survival according to PIK3CA mutation status

From: PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated with chagasic megaesophagus and are associated with a worse patient outcome

Groups

   

Time

  

Variable

Total

N events

6 months

1 year

3 years

5 years

Median survival

p-value

CM/ESCC

WT

13

10

79.4%

72.2%

43.3%

28.9%

2 years

< 0.001 *

MUT

5

5

20.0%

0.0%

0.0%

0.0%

5 months

ESCC

WT

24

22

82.6%

64.7%

32.6%

14.5%

2 years

0.405

MUT

4

4

80.0%

80.0%

60.0%

0.0%

2.5 years

  1. *Log-rank test. CM/ESCC – chagasic megaesophagus associated with esophageal squamous cell carcinoma; ESCC – esophageal squamous cell carcinoma without chagasic megaesophagus; WT – wild-type; MUT – mutated; Bold numbers - statistical significance
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Infectious Agents and Cancer

ISSN: 1750-9378

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