|
Variable
|
MFN2 expression
|
P value
|
|---|
|
High expression
|
Low expression
|
|---|
|
Sample size
|
33
|
74
| |
|
Age, years
|
0.179
|
|
> 50
|
15 (45.5%)
|
44 (59.5%)
| |
|
≤ 50
|
18 (54.5%)
|
30 (40.5%)
| |
|
Gender
|
0.844
|
|
Male
|
29 (87.9%)
|
64 (86.5%)
| |
|
Female
|
4 (12.1%)
|
10 (13.5%)
| |
|
AFP, ng/mL
|
0.420
|
|
< 20
|
10 (30.3%)
|
17 (23.0%)
| |
|
≥ 20
|
23 (69.7%)
|
57 (77.0%)
| |
|
Cirrhosis
|
0.049
|
|
Yes
|
30 (90.9%)
|
55 (74.3%)
| |
|
No
|
3 (9.1%)
|
19 (25.7%)
| |
|
Tumor size, cm
|
0.128
|
|
< 5
|
9 (27.3%)
|
11 (14.9%)
| |
|
≥ 5
|
24 (72.7%)
|
63 (85.1%)
| |
|
Differentiation
|
0.202
|
|
Well-moderate
|
6 (18.2%)
|
7 (9.5%)
| |
|
Poor-undifferentiated
|
27 (81.8%)
|
67 (90.5%)
| |
|
TNM stage
|
0.196
|
|
I–II
|
15 (45.5%)
|
24 (32.4%)
| |
|
III–IV
|
18 (54.5%)
|
50 (67.6%)
| |
|
Vascular invasion
|
0.192
|
|
Yes
|
4 (12.1%)
|
17 (23.0%)
| |
|
No
|
29 (87.9%)
|
57 (77.0%)
| |
- Abbreviations: MFN2 Mitofusin-2, AFP alpha-fetoprotein
