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Table 2 Preoperative serum levels of IL6 (pg/ml) in relation to other variables for men who underwent radical prostatectomy and had available information on serum IL6 (n = 98)

From: The influence of prostatic Cutibacterium acnes infection on serum levels of IL6 and CXCL8 in prostate cancer patients

Total population (n = 98)
 Median serum IL6, pg/ml (min-max) 1.09 (0.30–3.76)   
By C. acnes category C. acnes + (n = 60) C. acnes- (n = 38)  
 Median serum IL6, pg/ml (min-max) 1.04 (0.35–3.76) 1.16 (0.30–3.13) p = 0.106a
Gleason sum Gleason 6 (n = 36) Gleason 3 + 4 (n = 42) Gleason 4 + 3 (n = 16) Gleason 8+ (n = 4)  
 Median serum IL6, pg/ml (min-max) 1.02 (0.3–3.76) 1.09 (0.45–3.13) 1.14 (0.47–2.05) 1.12 (0.7–1.37) p = 0.836a
Positive sugical margins No (n = 64) Yes (n = 34)  
 Median serum IL6, pg/ml (min-max) 1.12 (0.3–3.76) 1.03 (0.39–2.97) p = 0.420a
pT stage pT2 (n = 87) pT3 (n = 11)  
 Median serum IL6, pg/ml (min-max) 1.1 (0.3–3.76) 1.05 (0.61–2.06) p = 0.862a
PSA
By PSA quartile < 4.6 ng/ml ≥4.6, < 6.4 ng/ml ≥6.4, < 9.0 ng/ml ≥9 ng/ml  
 Median serum IL6, pg/ml (min-max) 1.02 (0.45–2.88) 1.08 (0.47–2.23) 1.12 (0.3–3.13) 1.16 (0.39–3.76) p = 0.601a
Non-parametric correlation
 Correlation coefficient 0.058     p = 0.571b
Age
By age quartile < 61.3 years ≥61.3, < 64.7 years ≥64.7, < 67.1 years ≥67.1 years  
 Median serum IL6, pg/ml (min-max) 1.09 (0.3–3.13) 0.93 (0.39–2.97) 1.17 (0.47–3.76) 1.11 (0.35–2.88) p = 0.416a
Non-parametric correlation
 Correlation coefficient 0.113     p = 0.270b
Prostate volume
By volume quartile 10–26 ml 27–33 ml 34–50 ml 51–138 ml  
 Median serum IL6, pg/ml (min-max) 1.39 (0.3–3.76) 1.1 (0.56–2.68) 1.06 (0.39–2.73) 1.1 (0.35–2.78) p = 0.397a
Non-parametric correlation
Correlation coefficient −0.106     p = 0.321b
  1. ap-value fron Kruskal-Wallis Test/Mann-Whitney U Test; bp-value from Spearman correllation