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Table 2 Preoperative serum levels of IL6 (pg/ml) in relation to other variables for men who underwent radical prostatectomy and had available information on serum IL6 (n = 98)

From: The influence of prostatic Cutibacterium acnes infection on serum levels of IL6 and CXCL8 in prostate cancer patients

Total population (n = 98)

 Median serum IL6, pg/ml (min-max)

1.09 (0.30–3.76)

  

By C. acnes category

C. acnes + (n = 60)

C. acnes- (n = 38)

 

 Median serum IL6, pg/ml (min-max)

1.04 (0.35–3.76)

1.16 (0.30–3.13)

p = 0.106a

Gleason sum

Gleason 6 (n = 36)

Gleason 3 + 4 (n = 42)

Gleason 4 + 3 (n = 16)

Gleason 8+ (n = 4)

 

 Median serum IL6, pg/ml (min-max)

1.02 (0.3–3.76)

1.09 (0.45–3.13)

1.14 (0.47–2.05)

1.12 (0.7–1.37)

p = 0.836a

Positive sugical margins

No (n = 64)

Yes (n = 34)

 

 Median serum IL6, pg/ml (min-max)

1.12 (0.3–3.76)

1.03 (0.39–2.97)

p = 0.420a

pT stage

pT2 (n = 87)

pT3 (n = 11)

 

 Median serum IL6, pg/ml (min-max)

1.1 (0.3–3.76)

1.05 (0.61–2.06)

p = 0.862a

PSA

By PSA quartile

< 4.6 ng/ml

≥4.6, < 6.4 ng/ml

≥6.4, < 9.0 ng/ml

≥9 ng/ml

 

 Median serum IL6, pg/ml (min-max)

1.02 (0.45–2.88)

1.08 (0.47–2.23)

1.12 (0.3–3.13)

1.16 (0.39–3.76)

p = 0.601a

Non-parametric correlation

 Correlation coefficient

0.058

   

p = 0.571b

Age

By age quartile

< 61.3 years

≥61.3, < 64.7 years

≥64.7, < 67.1 years

≥67.1 years

 

 Median serum IL6, pg/ml (min-max)

1.09 (0.3–3.13)

0.93 (0.39–2.97)

1.17 (0.47–3.76)

1.11 (0.35–2.88)

p = 0.416a

Non-parametric correlation

 Correlation coefficient

0.113

   

p = 0.270b

Prostate volume

By volume quartile

10–26 ml

27–33 ml

34–50 ml

51–138 ml

 

 Median serum IL6, pg/ml (min-max)

1.39 (0.3–3.76)

1.1 (0.56–2.68)

1.06 (0.39–2.73)

1.1 (0.35–2.78)

p = 0.397a

Non-parametric correlation

Correlation coefficient

−0.106

   

p = 0.321b

  1. ap-value fron Kruskal-Wallis Test/Mann-Whitney U Test; bp-value from Spearman correllation