Table 1 Studies on HPV16 variants in head and neck cancers
From: Human papillomavirus genome variants and head and neck cancers: a perspective
Study | Country | N HPV16 + samples | Seq. | Variant lineage (n) | Non lineage specific variants (n) |
|---|---|---|---|---|---|
Gillison 2000 [67] | USA | 52 HNC | E6 | 39 Eur; 9 Asian; 2 NA; 1 Afr-1 | 20 T350G 6 A131G |
Hoffmann 2004 [70] | DE | 21 HNC (5 OPC) | E6/E7 | Â | 8 T350G (2 in OPC) 7 A131G (1 in OPC) |
Badaracco 2007 [62] | IT | 13 HNC (5 TC) | L1 | 9 Eur 2 Af-2; 1 AA | Â |
Agrawal 2008 [61] | USA | 14 HNC | E6 | 13 Eur 1 As | 3 T350G |
Boscolo Rizzo 2009 [68] | IT | 8 HNC (4 OPC) | E6 | Â | 5 T350G |
Blakaj 2012 [65] | USA | 43 HNC (28 OPC) | E6 | 31 Eur 7 AA; 3 Af | Â |
Du 2012 [66] | SW | 108 TC | E6 | 51(/55) EUR | 43 T350G 21 A131G |
Barbieri 2014 [63] | IT | 51 OPC | L1 | 41 Eur 10 Af | Â |
Hassani 2015 [69] | JP | 10 TC | E6 | Â | 8 T350G (1/3 T350G in tonsillitis) |
Betiol 2016 [64] | BR | 21 HNC (3 OPC) | E6 | 12 Eur 9 AA or NA1 | Â |