Table 2 Distribution of the PreS1 mutation prevalent among chronic hepatitis B patients according to clinical status

K13E

8

E

0

2

2

4

N14K

5

E

1

2

2

0

H15Y

5

E

1

2

2

0

N19T

5

E

0

2

1

2

B and T-cell

P25L

6

E

0

1

1

2

&

N29K

8

A

1

2

2

3

Hepatocyte-binding site

P30Q

7

A

2

2

2

3

A35E

8

E

0

0

5

3

R38K

14

E

2

3

5

4

R38G

4

E

1

0

1

2

W42G

4

E

0

1

0

3

H44L

11

E

2

1

4

4

V49A

6

A

0

3

1

2

T52R

5

E

1

1

1

2

P64S

4

E

1

1

2

0

S promoter (nt 3019-3201)

V80I

7

A

2

0

2

3

K85Q

4

E

2

1

1

0

S90T

6

A

1

3

0

2

S100V

4

E

1

1

2

0