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Table 2 Demographic data, exposure, and HPV-related disease history among participants segregated by oral swab statusf

From: Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners

Characteristic Patients (N = 198) Partners (N = 198)
Swab positive (N = 28) Swab negative (N = 170) p-Value Swab positive (N = 30) Swab negative (N = 168) p-value
Age, years
  < 55 12 (42.9 %) 76 (44.7 %) .86 15 (50 %) 93 (56 %) .54
  ≥ 55 16 (57.1 %) 94 (55.3 %) 15 (50 %) 73 (44 %)
Sex
 Female 5 (17.9 %) 32 (18.8 %) 1.0 26 (86.7 %) 135 (80.4 %) .61
 Male 23 (82.1 %) 138 (81.2 %) 4 (13.3 %) 33 (19.6 %)
Race
 White 22 (78.6 %) 156 (91.8 %) .032 23 (76.7 %) 134 (79.8 %) .70
 Other 6 (21.4 %) 14 (8.2 %) 7 (23.3 %) 34 (20.2 %)
Smoking statusa
 Former/never 14 (70.0 %) 80 (71.4 %) .90 13 (61.9 %) 61 (67.8 %) .61
 Current 6 (30 %) 32 (28.6 %) 8 (38.1 %) 29 (32.2 %)
Prior alcohol useb
 None 3 (11.1 %) 15 (8.9 %) .72 6 (20 %) 34 (21.1 %) .89
 Yes 24 (88.9 %) 154 (91.1 %) 24 (80 %) 127 (78.9 %)
Prior HPV-related disease
 None 28 (100.0 %) 157 (93.5 %) .37 23 (76.7 %) 133 (80.1 %) .67
 Yes 0 (0.0 %) 11 (6.5 %) 7 (23.3 %) 33 (19.9 %)
Prior benign HPV-related diseasec
 None 28 (100.0 %) 165 (97.1 %) 1.0 30 (100 %) 161 (95.8 %) .60
 Yes 0 (0.0 %) 5 (2.9 %) 0 (0 %) 7 (4.2 %)
Prior HPV-related malignancyd
 None 27 (96.4 %) 165 (97.1 %) 1.0 29 (96.7 %) 163 (97 %) 1.0
 Yes 1 (3.6 %) 5 (2.9 %) 1 (3.3 %) 5 (3 %)
HPV status of oropharyngeal tumore
 Negative 2 (11.8 %) 14 (11 %) 1.0 2 (10.5 %) 14 (11.2 %) 1.0
 Positive 15 (88.2 %) 113 (89 %) 17 (89.5 %) 111 (88.8 %)
Oral mouth swab status of matched pair
 HPV Negative 9 (32.1 %) 159 (93.5 %) <.001 11 (36.7 %) 159 (94.6 %) <.001
 HPV Positive 19 (67.9 %) 11 (6.5 %)   19 (63.3 %) 9 (5.4 %)  
  1. a8 swab positive and 58 swab negative patients had missing data on smoking; 1 swab positive and 1 swab negative patient had missing data on prior alcohol use
  2. b9 swab positive and 78 swab negative partners had missing data on smoking; 7 swab negative partners had missing data on prior alcohol use
  3. cbenign HPV-related disease defined as CIN I-III, dysplasia
  4. dCervical cancer, anal cancer, prior HNSCC cancer
  5. eBy p16 IHC (N = 121) or HPV ISH (N = 104); data were unavailable for 54 patients
  6. fPercentages are calculated as a column percentage