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Table 3 Correlation between HPV status and clinical parameters in Kazakh patients with ESCC

From: p53 expression but not p16INK4A correlates with human papillomavirus-associated esophageal squamous cell carcinoma in Kazakh population

Clinical properties Total HPV status (n/%)
Negative (%) Positive (%) P value
Gender
  Male 78 42(62.7 %) 36(64.3 %) 0.855
  Female 45 25(37.3 %) 20(35.7 %)
Age (mean)
  <57 55 29(43.9 %) 26(47.3 %) 0.714
  ≥57 66 37(56.1 %) 29(52.7 %)
Histopathological gradea
  Well 28 15(22.4 %) 13(23.6 %) 0.937
  Moderate 77 42(62.7 %) 35(63.6 %)
  Poor 17 10(14.9) 7(12.7 %)
Invasion depth
  T1-T2 59 37(55.2 %) 22(40.0 %) 0.094
  T3-T4 63 30(44.8 %) 33(60.0 %)
Lymphatic invasion
  N0 55 28(43.8 %) 27(50.9 %) 0.438
  N1-N3 62 36(56.2 %) 26(49.1 %)
TNM Staging
  I/II 74 40(61.5 %) 34(65.4 %) 0.668
  III/IV 43 25(38.5 %) 18(34.6 %)
  1. a Well differentiation vs. moderate + poor differentiation