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Table 3 Correlation between HPV status and clinical parameters in Kazakh patients with ESCC

From: p53 expression but not p16INK4A correlates with human papillomavirus-associated esophageal squamous cell carcinoma in Kazakh population

Clinical properties

Total

HPV status (n/%)

Negative (%)

Positive (%)

P value

Gender

  Male

78

42(62.7 %)

36(64.3 %)

0.855

  Female

45

25(37.3 %)

20(35.7 %)

Age (mean)

  <57

55

29(43.9 %)

26(47.3 %)

0.714

  ≥57

66

37(56.1 %)

29(52.7 %)

Histopathological gradea

  Well

28

15(22.4 %)

13(23.6 %)

0.937

  Moderate

77

42(62.7 %)

35(63.6 %)

  Poor

17

10(14.9)

7(12.7 %)

Invasion depth

  T1-T2

59

37(55.2 %)

22(40.0 %)

0.094

  T3-T4

63

30(44.8 %)

33(60.0 %)

Lymphatic invasion

  N0

55

28(43.8 %)

27(50.9 %)

0.438

  N1-N3

62

36(56.2 %)

26(49.1 %)

TNM Staging

  I/II

74

40(61.5 %)

34(65.4 %)

0.668

  III/IV

43

25(38.5 %)

18(34.6 %)

  1. a Well differentiation vs. moderate + poor differentiation