Fig. 1

Phylogenetic analyses of HPV isolate Pak01. a. The radiating NJ tree of HPV Pak01 and Pak02 with other HPV types having full-length genome sequences available from GenBank was constructed using MEGA version 5.05 [57]. The HPV Pak01 and Pak02 isolates (highlighted in gray) cluster with HPV type 16 reference sequence (accession no. NC_001526.2) with 100 % bootstrap support, in HPV16 species which include HPV types 16, 31, 35, 33, 52, 58 and 67 [1] and collectively belongs to α9 in genus alpha [26]. The annotation of species and genera in the tree follows Bernard and colleagues [26]. The bar indicates substitutions per site. b. The circular NJ tree was generated by phylogenetic analysis of HPV Pak01 and Pak02 with HPV 16 isolates having full-length genome sequences available from GenBank. The HPV Pak01 and Pak02 isolate (highlighted in gray) clusters with HPV type 16 isolates JP02789 from Japan and Qv00512 from Costa Rica [29]. The bracket parenthesis indicates substitutions per site