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Figure 1 | Infectious Agents and Cancer

Figure 1

From: HIV-1 Tat induces DNMT over-expression through microRNA dysregulation in HIV-related non Hodgkin lymphomas

Figure 1

Expression of DNMTs in HIV+vs. HIV-tumors. (a) Relative expression of DNMT1, DNMT3a/b in HIV+ vs. HIV- tumors by RT-qPCR. Up-regulation of all these genes is observed in HIV+ samples (p < 0.05). (b-c) IHC using an anti-DNMT1 antibody in HIV-negative cases (b) and HIV-positive cases (c). (d-e) IHC for DNMT3a in HIV-negative (d) and positive (e) cases. Up-regulation of DNMT1 and DNMT3a was detected in HIV-positive tumors. None of the antibodies tested for DNMT3b was useful for IHC.

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Infectious Agents and Cancer

ISSN: 1750-9378

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