Table 4 Comparison MDM2 SNP309 allele distribution among oral contraceptive users and non-users between LSIL, HSIL and normal cytology (control)
Cases | Controld | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP 309 rs2278744 | Total SILa | LSILb | HSILc | |||||||||
Alleles | Yes | No | Total | Yes | No | Total | Yes | No | Total | Yes | No | Total |
T | 79 (0.58) | 175 (0.63) | 254 (0.61) | 56 (0.57) | 109 (0.68) | 165 (0.63) | 23 (0.60) | 66 (0.58) | 89 (0.59) | 29 (0.60) | 63 (0.66) | 92 (0.64) |
G | 57 (0.42) | 101 (0.37) | 158 (0.39) | 42 (0.43) | 53 (0.32) | 95 (0.37) | 15 (0.40) | 48 (0.42) | 63 (0.41) | 19 (0.40) | 33 (0.34) | 52 (0.36) |
Genotypes | ||||||||||||
TT | 22 (0.32) | 52 (0.38) | 74 (0.36) | 17 (0.35) | 37 (0.46) | 54 (0.41) | 5 (0.26) | 15 (0.27) | 20 (0.26) | 9 (0.37) | 21 (0.44) | 30 (0.42) |
TG | 35 (0.51) | 71 (0.51) | 106 (0.51) | 22 (0.45) | 35 (0.43) | 57 (0.44) | 13 (0.69) | 36 (0.63) | 49 (0.64) | 11 (0.46) | 21 (0.44) | 32 (0.44) |
GG | 11 (0.17) | 15 (0.11) | 26 (0.13) | 10 (0.20) | 9 (0.11) | 19 (0.15) | 1 (0.05) | 6 (0.10) | 7 (0.10) | 4 (0.17) | 6 (0.12) | 10 (0.14) |