Differences in the mutation of the p53 gene in exons 6 and 7 in cervical samples from HIV- and HPV-infected women

Table 1 Distribution of mutations in the p53 gene in HIV group and control group

Cytologic findings	Total samples		p53 mutation		Total samples		p53 mutation		* p
	N	%	N	%	N	%	N	%	* p
Normal Cytology	70	84.3	12	17.1	21	56.8	4	19.0	0.4956
ASC-H	2	2.4	1	50.0	6	16.2	-		-
LSIL	10	12.1	2	20.0	9	24.3	3	33.3	0.3303
HSIL	1	12	1	100.0	1	2.7	-		-
TOTAL	83	100.0	16	19.3	37	100.0	7	18.9	0.4896

HPV, human papillomavirus; HIV, human immunodeficiency virus; cytologic findings (according to Bethesda System 2001): atypical squamous cells of undetermined significance, cannot exclude high-grade squamous intraepithelial lesion (ASC-H); low-grade squamous intraepithelial lesion (LSIL); high-grade squamous intraepithelial lesion (HSIL).
*p < 0.05 was considered significant.

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