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Table 2 Location of all amino acid mutations present in this study

From: Identification of a novel variant of LMP-1 of EBV in patients with endemic Burkitt lymphoma in western Kenya

Number of Samples

LMP-1 Type

T cell epitope

 
  

CTAR 3

JAK binding site

 

CTAR 2

  

Amino acid position

  

313

318

321

322

328

331

334

338

343

344

345

346

347

348

349

350

351

352

354

356

366

372

 

B95.8 RefSeq#

S

G

P

Q

E

G

Q

L

G

G

G

H

S

H

D

S

G

H

G

D

S

D

1

B'

 

N

 

E

  

R

S

         

R

  

T

 

3

B'

   

E

  

R

S

         

R

  

T

 

2

B'

   

E

  

R

S

            

T

 

1

B95.8

                      

1

B95.8'

                   

N

  

3

B95.8'

                    

T

 

1

B95.8'

                 

N

  

T

 

22

C

   

N

  

R

S

 

*

*

*

*

*

*

*

*

*

  

T

 

1

C'

   

N

G

 

R

S

 

*

*

*

*

*

*

*

*

*

  

T

 

2

C'

   

N

  

R

S

 

*

*

*

*

*

*

*

*

*

  

T

H

1

C'

   

N

  

R

S

 

*

*

*

*

*

*

*

*

*

S

 

T

G

1

C'

  

S

N

  

R

S

 

*

*

*

*

*

*

*

*

*

  

T

 

10

K'

 

K

 

E

  

R

S

            

T

 

11

K

 

K

 

E

  

R

S

         

R

  

T

 

1

D'

P

  

T

 

Q

 

P

            

T

 
  1. Sequences are grouped according to the scheme devised by Sandvej et al. [12], with amino acid mutations labeled at sites along LMP-1 protein sequence. Novel K variant amino acid changes are also labeled.
  2. # Stands for B95.8 reference sequence. * Stands for amino acid deletion.
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Infectious Agents and Cancer

ISSN: 1750-9378

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