Volume 7 Supplement 1

Proceedings of the 13th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies (ICMAOI)

Open Access

Prevalence of cervical and anal warts among HIV patients on ARV Nigerian special treatment center

  • Modupe Onigbogi1Email author,
  • Omobola Ojo1,
  • Olanrewaju Onigbogi1 and
  • Oluwaseun Akinyemi2
Infectious Agents and Cancer20127(Suppl 1):O13

https://doi.org/10.1186/1750-9378-7-S1-O13

Published: 19 April 2012

Background

With the introduction of HAART in many HIV treatment centers in Nigeria, there has been a decreased incidence of AIDS-related mortality and growing concern about the incidence of AIDS specific and non-AIDS specific cancers. This study thus sought to investigate patterns and incidence of cervical and anal warts among patients in a Special Treatment Center (SPC) before being diagnosed of having HIV and after starting ARVs.

Material and methods

We linked results from a population-based HIV registry in our SPC with that of two cancer registries and evaluated the risk of developing anal or cervical warts a year prior to onset of ARV and a year after commencement of HAART. Standardized incidence ratios (SIRs) were calculated to relate presence of cervical and anal warts in people with AIDS to that in the general population. We also used logistic regression with 95% confidential interval to compare risk according to demographic factors and CD4 count.

Results

The study involved 542 patients diagnosed with HIV within the two years of the study. Persons with AIDS had elevated risks of cervical warts (SIR=11.7, 95% CI 6.2-14.4, n=52) and anal warts (SIR=1.8, 95% CI 1.3-2.7, n=13). Risk for cervical warts increased with increasing time relative to AIDS onset (p=0.02), this trend was not significant for anal warts (p=0.12). Risk of developing both warts was unrelated to CD4 count at onset of treatment (p=0.43).

Conclusions

There is a modest excess risk of developing cervical and anal warts among this group of patients. The risk seems to increase with increasing years on ARVs. This is not related to the immune state of the patients. There is a need to pay attention to patients on ARV therapy as they advance in years with ARV medication.

Authors’ Affiliations

(1)
Department of Community Health and Primary Care, CMUL, University of Lagos
(2)
Department of Community Medicine, University College Hospital

Copyright

© Onigbogi et al; licensee BioMed Central Ltd. 2012

This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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