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Table 2 Agreement between ISH and Consensus PCR to detect HPV-DNA in OSCC and OPSCC

From: Evaluation of a combined triple method to detect causative HPV in oral and oropharyngeal squamous cell carcinomas: p16 Immunohistochemistry, Consensus PCR HPV-DNA, and In Situ Hybridization

ISH results Including LR and HR

No. of cases examined by PCR (%)

Sensitivity

Specificity

K

Total observed agreement (ISH/PCR)

Total expected agreement (ISH/PCR)

 

Diagnosis

Negative

Positive

      

Negative

56(90.3%)

4(6.5%)

33.3%

100%

0.44

58(93.5%)

83%

 

Positive

0(0%)

2(3.2%)

      

Negative

11(57.9%)

2(10.5%)

60%

78.5%

0.38

14(73.7%)

58%

 

Positive

3(15.8%)

3(15.8%)

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