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Prostate cancer: histopathological analysis of 66 cases


In the United States and Europe, prostate cancer is the most common male malignancy and the second leading cause of cancer death after lung cancer. However, in spite of under-estimation and reporting of cancer burden in Pathology-based cancer registries in the developing countries; prostate cancer is now ranked among the emerging male malignancy.


To demonstrate that prostate cancer is common among Nigerian males.

Materials and methods

This is a 5-year retrospective histopathological analysis of prostate cancer diagnosed between January 2005- December 2009 in the Department of Pathology, University of Abuja Teaching Hospital, Gwagwalada, Abuja. The tumours were classified based on WHO classification of Prostatic tumours. Histological grading was done using Gleason grading system.


Sixty-six (66) cases of prostate cancer were reviewed. The age range was between 40-89 years with a mean of 64.5 years. There were two bimodal age peaks at the seventh and eighth decades respectively. The surgical procedures were Trucut biopsies 64 (96.9%) and prostatectomy 2 (3.1%). The Gleason scores range from 2 to 10. Three (4.5%) patients were seen before the age of 50 years. There were 9 (13.6%) cases of well differentiated, 37 (56.0%) cases of moderately differentiated and 20 (30.4%) cases of poorly differentiated adenocarcinoma. No other histological types were seen.


In this study, there were bimodal age peaks of prostate cancer at the sixth and seventh decades, while moderately differentiated adenocarcinoma is the most common presentation.


Publication of this article was funded in part by the University of Florida Open-Access Publishing Fund.

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Correspondence to Olabode Peter Oluwole.

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This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Oluwole, O.P., Murkthar, A.U. & Amaechina, C. Prostate cancer: histopathological analysis of 66 cases. Infect Agents Cancer 6 (Suppl 1), A4 (2011).

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