Performance of the digene LQ, RH and PS HPVs genotyping systems on clinical samples and comparison with HC2 and PCR-based Linear Array

Table 3 HPV positive samples, single and multiple infections per assay among the 305 samples included in the study.

	HPV+		Single infections		Multiple infections		P ^&
TEST (common genotypes)*	N	%**	N	%#	N	%#
*HC2/LA vs. LQ or RH*	267	87.54	152	56.93	115	43.07
LQ	265	86.89	173	65.28	92	34.72	0.048
RH	263	86.23	194	73.76	69	26.24	<0.01
*HC2/LA vs*. PS	110	36.07	101	91.82	9	8.18
PS	91	29.84	87	95.60	4	4.40	0.278

"*": Common genotypes for HC2/LA vs LQ or RH: HPV16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 82; Common genotypes for HC2/LA vs PS: HPV16, 18, 45 "**": % among total of tested samples (n = 305); "#": % among positive samples; HC2: Hybrid Capture 2 System; LA: Linear Array;"&": p-value for the comparison of the proportion of multiple infections between LA and LQ, RH and PS.

ISSN: 1750-9378