Table 1 Confounding tumor look-alikes.
Tumor | Subtype examples/confounding factors | Presentation or clinical classification |
|---|---|---|
Fungal infections | African histoplasmosis | Kaposi’s sarcoma |
Entomophthoromycosis – Basidiobolus ranarum | NHL | |
HIV-1 lymphadenopathy, follicular hyperplasia | NHL | |
Viral lymphadenopathy | EBV lymphadenopathy or lymphoproliferative disorders | NHL |
HHV-8 lymphoblastic lymphoma | Burkitt lymphoma | |
Castleman’s disease | Atypical hyperplasia | |
Pediatric small round cell tumors | Undifferentiated neuroblastoma | Burkitt lymphoma |
Primitive neuroectodermal tumors (PNET) | Burkitt lymphoma | |
Hodgkin’s disease | Lymphocyte predominant | Burkitt lymphoma |
Carcinomas | Poorly differentiated | NHL |