Table 2 Genes Dysregulated in EBV-positive AGS Cells
From: Epstein-Barr virus-specific methylation of human genes in gastric cancer cells
Gene Name | Gene Symbol | Fold Change* |
|---|---|---|
Downregulated Genes | ||
basic leucine-zipper transcription factor, ATF-like | BATF | -38 |
cyclooxygenase-2 | COX2 | -35 |
bone morphogenic protein-4 | BMP4 | -32 |
intercellular adhesion molecule-1 | ICAM1 | -22 |
trefoil factor-1 | TFF1 | -21 |
inhibitor of DNA binding-2 | ID2 | -14 |
heat shock protein-70 | HSP70 | -10 |
cyclin-dependent kinase-2 | CDK2 | -9 |
cyclin-D1 | CCND1 | -9 |
hypoxia inducible factor-1A | HIF1A | -9 |
breast cancer-1 | BRCA1 | -7 |
nucleostemin | NU | -7 |
cyclin-dependent kinase inhibitor-2A | CDKN2A/p16 | -6 |
inhibitor of DNA binding-4 | ID4 | -6 |
engrailed-1 | EN1 | -5 |
ATP-binding cassette, sub-family B, member 1 | ABCB1 | -3 |
MDM2 p53 binding protein | MDM2 | -3 |
Upregulated Genes | ||
insulin-like growth factor binding protein-3 | IGFBP3 | +40 |
tumor necrosis factor receptor-associated factor-1 | TRAF1 | +20 |
transmembrane prostate androgen-induced protein | TMEPAI | +10 |
tumor necrosis factor, superfamily member-10 | TNFSF10 | +8 |
B cell lymphoma-2-like-1 | BCL2L1 | +7 |
baculoviral IAP repeat containing-3 | BIRC3 | +5 |
hexokinase-1 | HK1 | +5 |
FOS-like antigen-1 | FOSL1 | +3 |