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Table 2 Association between HLA alleles and KSHV DNA detection in saliva and peripheral blood among children in the Uganda Sickle Cell Anemia KSHV Study, 2001-2002

From: HLA polymorphisms and detection of kaposi sarcoma-associated herpesvirus DNA in saliva and peripheral blood among children and their mothers in the uganda sickle cell anemia KSHV Study

Allele # KSHV DNA positive/#KSHV DNA negative OR (95% CI) P-value # KSHV DNA positive/#KSHV DNA negative OR (95% CI) P-value
Saliva
A priori-motivated analyses
   Peripheral blood   
HLA-A*30       
   Absent 20/121 1   26/130 1  
   At least 1 *3001 5/29 1.1 (0.5-4.3) 0.5 3/23 0.6 (0.2-2.2) 0.8
   At least *3002 9/24 1.8 (0.8-4.1) 0.2 7/34 1.1 (0.5-2.7) 0.9
HLA-A*68       
   Absent 30/139 1   31/153 1  
   At least1*6801 0/6 0.0 0.6 1/5 1.0 (0.1-9.2) 1.0
   At least1*6802 4/29 0.5 (0.1-1.8) 0.3 4/29 0.7 (0.2-2.3) 0.6
HLA-DRB1*04       
   Absent 32/173 1   34/187 1  
   At least 1*0405 1/3 1.8 (0.1-5.2) 0.5 2/2 5.5 (0.7-40.3) 0.1
Explorative analyses       
   HLA-B*08       
   Absent 31/160 1   29/176 1  
   At least 1*0801 3/14 1.1 (0.3-4.1) 0.9 7/11 3.9 (1.4-10.8) 0.01
HLA-B*44       
   Absent 30/165 1   33/176 1  
   At least 1*4403 1/6 1.1 (0.1- 9.9) 0.9 2/6 1.9 (0.3-9.1) 0.2
   At least 1*4415 3/3 5.5 (1.1-28.6) 0.02 1/5 1.1 (0.1-9.2) 0.9
  1. KSHV: Kaposi-sarcoma-associated herpesvirus; OR: odds ratio; 95% CI: 95% confidence interval; HLA-A, -B, -DRB1: Human leucocyte antigen -A, -B, -DRB1