Background
Non AIDS-defining cancers (NADC) have emerged as a growing problem in the HIV-positive population, especially given that HIV-infected patients are living longer with antiretroviral therapy (ART). HIV-Tat protein appears to have oncogenic properties in colorectal cancer cells in vitro. To date, there has been no large series studying HIV-associated colon adenocarcinoma. Therefore, the aim of this study was to examine the clinicopathologic features of this NADC in a series of HIV-positive patients.