Table 5 Summary of case series investigating the prevalence of HPV DNA in tumour tissue from patients with ocular surface squamous neoplasias.
Study [Reference] | Detection method | Number HPV positive/total (%) | HPV type |
|---|---|---|---|
McDonnell et al, 1987 [46] | In situ hybridisation (ISH) | 0/28 (0%) | HPV 2, 6, 16, 18 |
McDonnell et al, 1989 [47] | PCR | 1/1 (100%) | HPV 16 |
Lauer et al, 1990 [48] | PCR | 4/5 (80%) | HPV 16 |
| Â | Â | 2/5 (40%) | HPV18 |
Odrich et al, 1991 [49] | PCR | 2/2 (100%) | HPV 16 |
McDonnell et a l, 1992 [50] | PCR | 33/38 (87%) | HPV 16 |
Tuppurainen et al, 1992 [51] | ISH and PCR | 0/4 (0%) | HPV 6, 11, 16 and 18 |
Serna et al, 1995 [52] | PCR | 1/9 (11%) | HPV 16 |
Nakamura et al, 1997 [53] | ISH and PCR | 2/8 (25%) | HPV 16 |
| Â | Â | 2/8 (25%) | HPV 18 |
Toth et al, 2000 [54] | PCR | 5/23 (9%) | HPV types not specified |
Eng et al, 2002 [55] | PCR | 0/20 (0%) | HPV 6, 11, 16, 18 |
Moubayed et al, 2004 [56] | ISH | 12/14 (86%) | HPV 16 |
| Â | Â | 13/14 (93%) | HPV 18 |
| Â | Â | 12/14 (86%) | HPV 6 and 11 |
Reszec and Sulkowski, 2005 [57] | PCR | 1/11 (9%) | HPV 16 |
| Â | Â | 1/11 (9%) | HPV 18 |