Table 1 HPV effects on oral cancer viability in vitro. HPV strains induced differential responses among CAL27, SCC-15 and SCC-25 cell lines. CAL27 viability was increased under all HPV experimental conditions, while SCC-15 and SCC-25 exhibited more nuanced, differential responses in cell viability to the HPV strains tested.
Cell viability | no HPV | HP16 | HPV18 | HPV16/18 |
|---|---|---|---|---|
CAL27 (% change) | 73% | 84% (+11%) | 95% (+22%) | 81% (+8%) |
SCC-15 (%change) | 89% | 87% (-2%) | 88% (-1%) | 45% (-44%) |
SCC-25 (% change) | 80% | 86% (+6%) | 79% (-1%) | 82% (+2%) |