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Figure 4 | Infectious Agents and Cancer

Figure 4

From: High risk HPV types 18 and 16 are potent modulators of oral squamous cell carcinoma phenotypes in vitro

Figure 4

Cell adhesion was altered by HPV18 and co-transfection of HPV16/18 in CAL27 and SCC-25 cells. (A) CAL27 adhesion was increased by HPV16 (+18%), HPV18 (+40%) and HPV16/18 (+26%) although only the increases among HPV18 and HPV16/18-transfectants were significant (n = 32, p < 0.01), as measured by 30-minute in vitro adhesion assays. (B) SCC-15 adhesion was slightly reduced by HPV16 (-15%), HPV18 (-11%) and HPV16/18 (-12%), although these differences were not significant (n = 48, p > 0.05). (C) SCC-15 adhesion was increased slightly by HPV16 (+8%) but was decreased significantly by HPV18 (-24%) and HPV16/18 (-20%) (n = 32, p < 0.01).

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